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Infection

货号 产品名 CAS号 信息
CSN17006 (2S,2a'E,2a1'S,4'E,5S,6R,6'S,7'S,8'E,11'R,15'S,17a'R,20'R,20a'R)-6-((S)-sec-Butyl)-2a1',20'-dihydroxy-7'-(((2R,4S,5S,6S)-4-methoxy-5-(((2S,4S,5S,6S)-4-methoxy-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,6',8',19'-tetramethyl-2a1',5,6,6',7',10',11',14',15',17a',20',20a'-dodecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one benzoate 155569-91-8 Emamectin benzoate acts as an activator of chloride channel via binding gamma aminobutyric acid (GABA) receptor and glutamate-gated chloride channels. It can disrupt nerve signals in arthropods.
CSN17010 (6R,7R)-7-((R)-2-Amino-2-(cyclohexa-1,4-dien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 38821-53-3 Cefradine is a first-generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin.
CSN17036 (S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrate(2:1) 138199-71-0 Levofloxacin Hemihydrate is antibiotic against gram-negative organisms, working by inhibiting the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
CSN17043 (2R,3S,4S,5S,6R)-6-(((3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-(((2R,3S,4R,5S)-3,4-Dihydroxy-5-(isobutyryloxy)-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-11-ethyl-8-hydroxy-18-((R)-1-hydroxyethyl)-9,13,15-trimethyl-2-oxooxacyclooctadeca-3,5,9,13,15-pentaen-3-yl)methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate 873857-62-6 Fidaxomicin is a macrocyclic antibiotic drug that inhibits RNA polymerase sigma subunit, and shows selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora.
CSN17049 1-(1-Adamantyl)ethylamine HCl 1501-84-4 Rimantadine HCl can inhibit influenza's viral replication possibly by preventing the uncoating of the virus's protective shells, used to treat influenzavirus A infection.
CSN17053 Clevudine 163252-36-6 Clevudine is an antiviral agent that used to treat hepatitis B.
CSN17086 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide 36791-04-5 Ribavirin blocks nucleic acid synthesis and inhibits both RNA and DNA viruses. Ribavirin is a nucleoside antimetabolite antiviral agent.
CSN17106 Miconazole 22916-47-8 Miconazole is a synthetic imidazole-derived antifungal used in the treatment of candidal skin infections, selectively affecting the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes.
CSN17109 Butoconazole nitrate 64872-77-1 Butoconazole nitrate is an anti-fungal agent and the IC50s of IL-2, TNFα, IFN and GM-CSF are 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively.
CSN52440 N-Phenyl-4-(3-phenylthioureido)benzenesulfonamide 245342-14-7
CSN17226 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride 121577-32-0 Gatifloxacin HCl is a fourth-generation fluoroquinolone antibiotic working by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV.
CSN17290 5-((2-(2-Butoxyethoxy)ethoxy)methyl)-6-propylbenzo[d][1,3]dioxole 51-03-6 Piperonyl Butoxide, a semisynthetic derivative of safrole, is used as a component of pesticide formulations.
CSN17320 GNF179 1261114-01-5 GNF179 is an anti-parasitic agent.
CSN64557 9-(((E)-4-((2S,3R,4R,5S)-3,4-Dihydroxy-5-(((2S,3S)-3-((2S,3S)-3-hydroxybutan-2-yl)oxiran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoyl)oxy)nonanoic acid 12650-69-0
CSN17371 BTZ043 1161233-85-7 BTZ043 is an antimycobacterial working by targeting mycobacterial cell wall synthesis by inhibiting DprE1.
CSN17472 Cefetamet pivoxil HCl 111696-23-2 Cefetamet Pivoxil HCl is a third-generation cephalosporin with activity against the major respiratory pathogens.
CSN17540 Sodium (1R,2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate 1192491-61-4 Avibactam Sodium is a synthetic non-β-lactam, covalent, slowly reversible β-lactamase inhibitor.
CSN17297 3,5-Dinitro-o-toluamide 148-01-6 2-Methyl-3,5-Dinitrobenzamide is a fodder additive for poultry, used to prevent coccidiosis infections.
CSN17230 Besifloxacin HCl 405165-61-9 Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic for the treatment of bacterial conjunctivitis, working by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV.
CSN17310 Asunaprevir 630420-16-5 Asunaprevir is an inhibitor of hepatitis C virus (HCV) NS3 protease.
CSN17182 OG-L002 1357302-64-7 OG-L002 is a selective inhibitor of LSD1 with IC50 of 20 nM.
CSN17007 Ertapenem 153832-46-3 Ertapenem is a carbapenem antibiotic. It is structurally very similar to meropenem in that it possesses a 1-β-methyl group.
CSN17327 Norvancomycin HCl 213997-73-0 Norvancomycin HCl is applicable for endocarditis, osteomyelitis, pneumonia, sepsis or soft tissue infections caused by Staphylococcus (including Methicillin-resistant strains and multidrug-resistant microbial strains).
CSN17411 (S)-2-Acetamido-N-((S)-1-(((S)-5-guanidino-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)-4-methylpentanamide hemisulfate 103476-89-7 Leupeptin Hemisulfate is a reversible serine/cysteine protease inhibitor, inhibits cathepsins B, H, L, and S, calpain, and trypsin.
CSN17443 MAC13243 1071638-38-4 MAC13243, an antibacterial agent, is a likely inhibitor of the bacterial lipoprotein targeting chaperone, LolA.
CSN17558 Grazoprevir potassium salt 1206524-86-8 MK-5172 potassium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN17236 Pefloxacin 70458-92-3 Pefloxacin is an an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse).
CSN17361 (S)-Tedizolid 1431699-67-0 (S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is an oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.
CSN17550 Posaconazole hydrate 1198769-38-8 Posaconazole is a lanosterol-14 demethylase inhibitor with an IC50 of 0.25 nM.
CSN17374 PSI-7976 1190308-01-0 PSI-7976, the isomer of PSI-7977, is an inhibitor of HCV RNA replication in the HCV replicon assay (EC50=1.07 μM).
CSN17544 Omadacycline mesylate 1196800-40-4 Omadacycline mesylate is a tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome.
CSN17502 Marbofloxacin HCl 115551-26-3 Marbofloxacin HCl is a potent antibiotic of which depends upon its inhibition of DNA-gyrase.
CSN17190 VER-82576 847559-80-2 NVP-BEP800 is a fully synthetic HSP90β inhibitor with IC50 of 58 nM, exhibits> 70-fold selectivity against Hsp90 family members Grp94 and Trap-1.
CSN17041 Helioxanthin 8-1 840529-13-7 Helioxanthin 8-1 is an analogue of helioxanthin, exhibiting significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of > 5/10/1.4/15 uM.
CSN17537 M2 ion channel blocker 1190215-03-2 M2 ion channel blocker is capable of inhibiting and blocking the activity of M2 ion channel and is an antiviral agent.
CSN17233 TBA-7371 1494675-86-3 DprE1-IN-1, a potent DprE1 inhibitor, with ic50 of 10 nM, also inhibits PDE6, with IC50 of 6 μM.
CSN17404 cis-Lomibuvir 1026785-59-0 VX-222 is a potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.
CSN17457 PLpro inhibitor 1093070-14-4 PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with IC50 of 2.6 μM.
CSN17308 Micafungin 235114-32-6 Micafungin is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.
CSN17309 Sodium 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,8,11,12,14,15,22,25-octahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5,19-dioxo-9-(4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzamido)-2,3,5,6,9,10,11,12,14a,15,16,17,19,20,23,25a-hexadecahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl sulfate 208538-73-2 Micafungin sodium is an echinocandin antifungal drug, Micafungin inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls.
CSN17447 Omadacycline tosylate 1075240-43-5 Omadacycline tosylate is a tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome.
CSN17098 Bitoscanate 4044-65-9 p-Phenylene diisothiocyanate is an organic chemical compound used in the treatment of hookworms.
CSN17501 BI 224436 1155419-89-8 BI-224436 is an HIV-1 noncatalytic site integrase inhibitor with EC50 values of less than 15 nM against different HIV-1 laboratory strains.
CSN17125 Finafloxacin 209342-40-5 Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments.
CSN17357 Velpatasvir 1377049-84-7 Velpatasvir is an inhibitor of hepatitis C virus nonstructural protein 5A (NS5A) (genotype 1 (GT1) to GT6 replicons).
CSN17227 Valacyclovir 124832-26-4 Valacyclovir is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B.
CSN17463 SPK-601 1096687-52-3 SPK-601 is a potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor and is a useful antimicrobial agent.
CSN17495 Tigecycline mesylate 1135871-27-0 Tigecycline mesylate a first-in-class, broad spectrum antibiotic with activity against antibiotic-resistant organisms.
CSN17048 Rimantadine 13392-28-4 Rimantadine is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.
CSN17340 Polymyxin B Sulfate 1405-20-5 Polymyxin B sulphate is an antibiotic primarily used for resistant Gram-negative infections.
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