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CAS No.: 180288-69-1
Trastuzumab is a humanized IgG1 monoclonal antibody that binds to subdomain IV of HER2 receptor with high affinity and specifcity, inhibiting ligand-independent HER2 signalling and proteolytic cleavage of its extracellular domain.
描述
Trastuzumab is a humanized IgG1 monoclonal antibody that binds to subdomain IV of HER2 receptor with high affinity and specifcity, inhibiting ligand-independent HER2 signalling and proteolytic cleavage of its extracellular domain. It was the frst HER2-targeted therapy approved for the treatment of HER2-positive breast cancer.
同义词
Herceptin
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