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CAS No.: 1780259-94-0
Synonyms: ZK 756326 (hydrochloride);ZK-756326
ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist. ZK 756326 inhibited the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 muM. ZK 756326 was a full agonist of CCR8, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1.
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CAS号 | 1780259-94-0 | 储存条件 |
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分子式 | C21H30Cl2N2O3 | 运输 | 蓝冰 | |
分子量 | 429.38 | 别名 | ZK 756326 (hydrochloride);ZK-756326 |
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