CAS No.: 874911-96-3
ZK 756326 Catalog No. CSN17345
ZK756326 is a full agonist of CCR8（Chemokine receptor 8） with an IC50 of 1.8 μM, dose-responsively eliciting an increase in intracellular calcium and cross-desensitizing the response of the receptor to CCL1.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Petersen TP, Ritzen A, et al. A multistep continuous-flow system for rapid on-demand synthesis of receptor ligands. Org Lett. 2009 Nov 19;11(22):5134-7.
- [2] Haskell CA, Horuk R, et al. Identification and characterization of a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8. Mol Pharmacol. 2006 Jan;69(1):309-16.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 874911-96-3 | 储存条件 |
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| 分子式 | C21H28N2O3 | 运输 | 蓝冰 | |
| 分子量 | 356.46 | 别名 |
