CAS No.: 500-62-9
Yangonin/麻醉椒素 Catalog No. CSN12285
Synonyms: CCRIS-9372;NSC-212502;甲氧醉椒素
Yangonin, a natural product isolated and purified from the roots of Piper methysticum, possess significant binding affinity for the cannabinoid receptor CB1 and inhibits NF-κB activation through suppression of the transcriptional activity of the RelA/p65 subunit of NF-κB.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Ma J, Liang H, et al. Yangonin blocks tumor necrosis factor-α-induced nuclear factor-κB-dependent transcription by inhibiting the transactivation potential of the RelA/p65 subunit. J Pharmacol Sci. 2012;118(4):447-54.
- [2] Wruck CJ, Gotz ME, et al. Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation. Mol Pharmacol. 2008 Jun;73(6):1785-95.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 500-62-9 | 储存条件 |
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| 分子式 | C15H14O4 | 运输 | 蓝冰 | |
| 分子量 | 258.27 | 别名 | CCRIS-9372;NSC-212502;甲氧醉椒素 |
