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CAS No.: 1243243-89-1
Synonyms: C59;PORCN Inhibitor II
Wnt-C59 is a potent inhibitor of PORCN, as measured by prevention of Wnt3A activation (IC50 = 74 pM).
生物活性
靶点 | PORCN IC50:~74pM |
实验方案
技术信息
CAS号 | 1243243-89-1 | 储存条件 |
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分子式 | C25H21N3O | 运输 | 蓝冰 | |||||||||||||
分子量 | 379.45 | 别名 | C59;PORCN Inhibitor II | |||||||||||||
溶解度 |
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动物实验配方 |
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Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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human HT1080 cells | - | Function assay | - | Inhibition of porcupine activity (unknown origin) expressed in human HT1080 cells assessed as suppression of Wnt3A-mediated super top flash activity by STF luciferase assay, IC50=7.4e-05 μM. | 26522946 |
靶点 | Description | IC50 |
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PORCN | IC50:~74pM |
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