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CAS No.: 1246560-33-7
Synonyms: SB2343
VS-5584 is a potent and selective dual PI3K/mTOR inhibitor for mTOR, PI3Kα/β/δ/γ with IC50 of 3.4 nM and 2.6-21 nM.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02372227 | Relapsed Malignant Mesotheliom... more >>a Collapse << | Phase 1 | Terminated | - | United States, Illinois ... more >> The University of Chicago Medical Center Chicago, Illinois, United States, 60637 United States, New York Memorial Sloane Kettering Cancer Center New York, New York, United States, 10065 United Kingdom University of Leicester Leicester, United Kingdom The Institute of Cancer Research Sutton Surrey, United Kingdom Collapse << |
NCT01991938 | Non Hematologic Cancers ... more >> Metastatic Cancer Lymphoma Collapse << | Phase 1 | Terminated(Lack of recruitment... more >> and the company's decision to de-prioritize 5584 development) Collapse << | - | United States, Arizona ... more >> HonorHealth Research Institute Scottsdale, Arizona, United States, 85258 United States, California Cedars-Sinai Medical Center Los Angeles, California, United States, 90048 United States, New York Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 United States, Tennessee Tennessee Oncology Nashville, Tennessee, United States, 37203 United Kingdom The Royal Marsden Sutton, London, United Kingdom, SM2 5PT Collapse << |
实验方案
技术信息
CAS号 | 1246560-33-7 | 储存条件 |
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分子式 | C17H22N8O | 运输 | 蓝冰 | |
分子量 | 354.41 | 别名 | SB2343 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02372227 | Relapsed Malignant Mesotheliom... more >>a Collapse << | Phase 1 | Terminated | - | United States, Illinois ... more >> The University of Chicago Medical Center Chicago, Illinois, United States, 60637 United States, New York Memorial Sloane Kettering Cancer Center New York, New York, United States, 10065 United Kingdom University of Leicester Leicester, United Kingdom The Institute of Cancer Research Sutton Surrey, United Kingdom Collapse << |
NCT01991938 | Non Hematologic Cancers ... more >> Metastatic Cancer Lymphoma Collapse << | Phase 1 | Terminated(Lack of recruitment... more >> and the company's decision to de-prioritize 5584 development) Collapse << | - | United States, Arizona ... more >> HonorHealth Research Institute Scottsdale, Arizona, United States, 85258 United States, California Cedars-Sinai Medical Center Los Angeles, California, United States, 90048 United States, New York Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 United States, Tennessee Tennessee Oncology Nashville, Tennessee, United States, 37203 United Kingdom The Royal Marsden Sutton, London, United Kingdom, SM2 5PT Collapse << |
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