CAS No.: 1166254-80-3
Voxvoganan Catalog No. CSN20538
Synonyms: LTX-109;Lytixar;Lytixar free base
LTX-109 is a synthetic antimicrobial peptide, showing activity against methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, daptomycin-nonsusceptible, and linezolid-nonsusceptible Staphylococcus aureus.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01223222 Gram-positive, Skin Infections... more >> Mild Eczema/Dermatoses Atopic Dermatitis Collapse << Phase 2 Completed - Hungary ... more >> Debreceni Egyetem Orvos-és Egészségtudományi Debrecen, Hungary, 4032 Miskolci Semmelweis Ignác Egészegügyi Központ és Miskolc, Hungary, 3529 Pécsi Tudományegyetem általános Orvostudom´nyi Centum Pécs, Hungary, 7624 Szeged Univesrity Hospital Szeged, Hungary, 6720 Collapse << NCT01158235 Nasal Carriers MRSA Phase 1 Phase 2 Completed - Sweden ... more >> Skåne University Hospital Malmö, Sweden, 205 02 Collapse << NCT01803035 Non-bullous Impetigo Phase 2 Completed - Dominican Republic ... more >> Dr. Robert Reid Cabral Children Hospital Santo Domingo, Dominican Republic Institute of Dermatology and and Skin Surgery Dr. Hubert Bogaert Diaz Santo Domingo, Dominican Republic Collapse << - 参考文献
- [1] Nilsson AC, Janson H, et al. LTX-109 is a novel agent for nasal decolonization of methicillin-resistant and -sensitive Staphylococcus aureus. Antimicrob Agents Chemother. 2015 Jan;59(1):145-51.
- [2] Isaksson J, Brandsdal BO, et al. A synthetic antimicrobial peptidomimetic (LTX 109): stereochemical impact on membrane disruption. J Med Chem. 2011 Aug 25;54(16):5786-95.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1166254-80-3 | 储存条件 |
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| 分子式 | C43H69N11O3 | 运输 | 蓝冰 | |
| 分子量 | 788.08 | 别名 | LTX-109;Lytixar;Lytixar free base |
