CAS No.: 165393-06-6
Urolithin C/尿石素C Catalog No. CSN27384
Synonyms: 尿石素C
Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Toubal S, Oiry C, Bayle M, Cros G, Neasta J. Urolithin C increases glucose-induced ERK activation which contributes to insulin secretion. Fundam Clin Pharmacol. 2020 Oct;34(5):571-580
- [2] Peipei Yin, et al. Urolithin C, a gut metabolite of ellagic acid, induces apoptosis in PC12 cells through a mitochondria-mediated pathway. RSC Advances. Issue 28, 2017.
- [3] Morgane Bayle, et al. Development and Validation of a Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry Method for the Determination of Urolithin C in Rat Plasma and Its Application to a Pharmacokinetic Study. J Pharm Biomed Anal. 2016 Nov 30;131:33-39.
- [4] Bayle M, Neasta J, Dall'Asta M, Gautheron G, Virsolvy A, Quignard JF, Youl E, Magous R, Guichou JF, Crozier A, Del Rio D, Cros G, Oiry C. The ellagitannin metabolite urolithin C is a glucose-dependent regulator of insulin secretion through activation of L-type calcium channels. Br J Pharmacol. 2019 Oct;176(20):4065-4078
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 165393-06-6 | 储存条件 |
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| 分子式 | C13H8O5 | 运输 | 蓝冰 | |||
| 分子量 | 244.20 | 别名 | 尿石素C | |||
| 溶解度 |
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动物实验配方 |
