CAS No.: 1635437-39-6
UMB-32 Catalog No. CSN20359
UMB-32 is an inhibitor of the BET bromodomain BRD4 (Kd = 550 nM; IC50 = 637 nM) and the bromodomain-containing transcription factor TAF1 (Kd = 560 nM) and TAF1L (Kd = 1.3 µM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Huang H, Liu S, Jean M, et al. A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association. Front Microbiol. 2017 Jun 7;8:1035.
- [2] McKeown MR, Shaw DL, et al. Biased multicomponent reactions to develop novel bromodomain inhibitors. J Med Chem. 2014 Nov 13;57(21):9019-27.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1635437-39-6 | 储存条件 |
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| 分子式 | C21H23N5O | 运输 | 蓝冰 | |
| 分子量 | 361.44 | 别名 |
