CAS No.: 522-97-4
Tetrahydroberberine,THB/四氢小檗碱 Catalog No. CSN12068
Synonyms: Canadine;NSC 36351;NSC 94918
Tetrahydroberberine is an isoquinoline alkaloid isolated and purified from the barks of Phellodendron chinense Schneid. It has micromolar affinity for dopamine D(2) (pK (i) = 6.08) and 5-HT(1A) (pK (i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors(5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK (i) < 5.00).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Lee TH, Kim KH, et al. Tetrahydroberberine, an isoquinoline alkaloid isolated from corydalis tuber, enhances gastrointestinal motor function. J Pharmacol Exp Ther. 2011 Sep;338(3):917-24.
- [2] Niwa M, Mibu H, et al. Dopaminergic unique affinity of tetrahydroberberine and l-tetrahydroberberine-d-camphor sulfonate. Pharmacology. 1991;43(6):329-36.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 522-97-4 | 储存条件 |
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| 分子式 | C20H21NO4 | 运输 | 蓝冰 | |
| 分子量 | 339.39 | 别名 | Canadine;NSC 36351;NSC 94918;Xanthopuccine;四氢小檗碱 |
