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CAS No.: 14636-12-5
Synonyms: Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys4-Cys9);Glycylpressin;Remestyp
Terlipressin, an analog of vasopressin, acts as vasoconstrictor via V1 receptors on arteriolar smooth muscle cells and can reduce visceral blood flow. It is used to treat hypotension.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT03038295 | Retinopathy of Prematurity | Phase 2 | Not yet recruiting | December 2019 | - |
NCT00838864 | Esophageal and Gastric Varices... more >> Gastrointestinal Hemorrhage Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Far Eastern Memorial Hospital Taipei, Taiwan, 22050 Collapse << |
NCT02726620 | Hypotension | Not Applicable | Active, not recruiting | December 31, 2018 | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Collapse << |
实验方案
技术信息
CAS号 | 14636-12-5 | 储存条件 |
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分子式 | C52H74N16O15S2 | 运输 | 蓝冰 | |||||
分子量 | 1227.37 | 别名 | Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys4-Cys9);Glycylpressin;Remestyp;特利加压素 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT03038295 | Retinopathy of Prematurity | Phase 2 | Not yet recruiting | December 2019 | - |
NCT00838864 | Esophageal and Gastric Varices... more >> Gastrointestinal Hemorrhage Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Far Eastern Memorial Hospital Taipei, Taiwan, 22050 Collapse << |
NCT02726620 | Hypotension | Not Applicable | Active, not recruiting | December 31, 2018 | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Collapse << |
NCT01278199 | Hemoptysis Ac... more >>ute Disease Collapse << | Not Applicable | Completed | - | France ... more >> Tenon Hospital, AP-HP Paris, France, 75012 Collapse << |
NCT02377141 | Liver Cirrhosis ... more >> Variceal Haemorrhage Collapse << | Not Applicable | Active, not recruiting | January 31, 2019 | United Kingdom ... more >> Royal Infirmary of Edinburgh Edinburgh, United Kingdom, EH16 4SA Glasgow Royal Infirmary Glasgow, United Kingdom, G4 0SF Collapse << |
NCT01079715 | Retinopathy of Prematurity | Phase 2 Phase 3 | Completed | - | Italy ... more >> Neonatal Intensive Care Unit - Azienda Ospedaliero-Universitaria Meyer Florence, Italy, I-50139 Neonatal Intensive Care Unit - Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico Milan, Italy, I-20122 Collapse << |
NCT01944410 | Traumatic Bone Cyst | Phase 1 | Completed | - | Iran, Islamic Republic of ... more >> RE Shiraz, CMF ward , Chamran hospital , Chamran avenue., Iran, Islamic Republic of Collapse << |
NCT01631890 | Bleeding Gastric Varices | Phase 3 | Withdrawn | June 2014 | India ... more >> Institute of Liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT02364297 | Portal Hypertension ... more >> Bleeding Gastric Varices Collapse << | Not Applicable | Recruiting | December 2018 | Spain ... more >> Hospital Germans Trias i Pujol Recruiting Badalona, Catalonia, Spain Contact: Rosa Morillas, MD ICU Liver Unit. Hospital Clinic of Barcelona Recruiting Barcelona, Catalonia, Spain, 08036 Contact: Angels Escorsell, MD 34932275400 ext 4030 aescor@clinic.cat Principal Investigator: Angels Escorsell, MD Hospital de la Santa Creu i Sant Pau Recruiting Barcelona, Catalonia, Spain Contact: Càndid Villanueva, MD cvillanueva@santpau.cat Hospital del Mar Recruiting Barcelona, Catalonia, Spain Contact: José Carrión, MD Hospital Arnau de Vilanova Recruiting Lleida, Spain Contact: Carles Aracil, MD carbla34@gmail.com Collapse << |
NCT01441453 | Surgery Hepat... more >>ocellular Carcinoma Collapse << | Not Applicable | Unknown | - | Italy ... more >> General Surgery and Organ Transplantation Unit, Policlinico Sant'Orsola-Malpighi Not yet recruiting Bologna, Italy, 40138 Contact: Matteo Cescon, MD, PhD matteo.cescon@unibo.it Principal Investigator: Matteo Cescon, MD, PhD Collapse << |
NCT01370161 | Decompensated Cirrhosis ... more >> Bleeding Varices Collapse << | Not Applicable | Completed | - | China, Shaanxi ... more >> Xijing Hospital of Digestive Diseases, Fourth Military Medical University Xi'an, Shaanxi, China, 710032 Collapse << |
NCT01383460 | Acute on Chronic Hepatic Failu... more >>re Collapse << | Phase 3 | Completed | - | India ... more >> Institute of liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT02937935 | Acute Kidney Injury With Cirrh... more >>osis Collapse << | Not Applicable | Not yet recruiting | July 1, 2019 | India ... more >> Institute of Liver and Biliary Sciences Recruiting New Delhi, Delhi, India, 110070 Collapse << |
NCT03145168 | Cirrhosis | Not Applicable | Not yet recruiting | July 25, 2019 | India ... more >> Institute of Liver and Biliary Sciences Recruiting New Delhi, Delhi, India, 110070 Collapse << |
NCT02049125 | - | - | Unknown | March 2018 | Brazil ... more >> Federal University of Espirito Santo Not yet recruiting Vitoria, Espirito Santo, Brazil, 29075-910 Contact: Luciana L Goncalves, Ph. D. lucianalofego@terra.com.br Principal Investigator: Luciana L Goncalves, Ph. D. Federal University of Rio Grande do Sul Recruiting Porto Alegre, Rio Grande do Sul, Brazil, 90035-903 Contact: Mario RA Silva, Assoc. Prof. marioreis@live.com Principal Investigator: Mario RA Silva, Assoc. Prof. University of Campinas Not yet recruiting Campinas, São Paulo, Brazil, 13083-887 Contact: Daniel FC Mazo, PhD Contact danielmazo@yahoo.com.br Principal Investigator: Daniel FC Mazo, PhD University of Sao Paulo Recruiting Sao Paulo, Brazil, 05403-010 Contact: Rafael O Ximenes, MD +55011 2661-3338 rximenes@gmail.com Principal Investigator: Alberto Q Farias, Assoc. Prof. Principal Investigator: Ana LC Martinelli, Assoc. Prof. Principal Investigator: Flair J Carrilho, Professor Collapse << |
NCT02788240 | Acute on Chronic Liver Failure | Not Applicable | Terminated | - | India ... more >> Institute of liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT02473341 | Alcoholic Hepatitis | Phase 3 | Recruiting | September 2019 | India ... more >> Department of Gastroenterology, D.M.C. and Hospital Recruiting Ludhiana, Punjab, India, 141001 Contact: Sandeep S Sidhu, DM 919814025085 dmcgastro@in.com Contact: Omesh Goyal, DM 919914821155 goyalomesh@yahoo.co.in Principal Investigator: Sandeep S Sidhu, D.M. Principal Investigator: Omesh Goyal, D.M. Collapse << |
NCT03530761 | - | - | Recruiting | December 31, 2019 | Korea, Republic of ... more >> SoonChunHyang University Bucheon Hospital Recruiting Bucheon, Gyeonggi Do, Korea, Republic of, 14584 Contact: Sang Gyune Kim, Professor 82-32-621-5079 mcnulty@schmc.ac.kr Principal Investigator: Sang Gyune Kim Collapse << |
NCT01640964 | Compensated Cirrhosis and Port... more >>al Hypertension Collapse << | Phase 2 | Completed | - | United Kingdom ... more >> Novartis Investigative Site Edinburgh, United Kingdom, EH16 4TJ Collapse << |
NCT01640964 | - | - | Completed | - | - |
NCT00863837 | Esophageal Variceal Rebleeding | Phase 4 | Unknown | December 2009 | - |
NCT03279419 | - | - | Recruiting | December 1, 2019 | United Kingdom ... more >> Univerity of Edinburgh and NHS Lothian Recruiting Edinburgh, United Kingdom Contact: Chric Coner chris.coner@ed.ac.uk Collapse << |
NCT02468063 | Cirrhosis With Septic Shock | Not Applicable | Completed | - | India ... more >> Institute of Liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT03162419 | Acute-On-Chronic Liver Failure | Not Applicable | Withdrawn(Lack of Funds.) | April 25, 2019 | India ... more >> Institute of Liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT01112852 | Esophageal Varices ... more >> Bleeding Collapse << | Phase 4 | Completed | - | - |
NCT01373606 | Hepatorenal Syndrome Type 1 | Phase 1 Phase 2 | Completed | - | Japan ... more >> Investigational site Kansai, Japan Investigational site Kanto, Japan Collapse << |
NCT00481572 | Septic Shock | Phase 2 | Completed | - | Italy ... more >> Department of Anesthesiology and Intensive care of the University of Rome "La Sapienza" Rome, Viale del Policlinico 155, Italy, 00161 Collapse << |
NCT00995839 | Septic Shock ... more >>Sepsis Collapse << | Phase 2 Phase 3 | Completed | - | Italy ... more >> Departement of Anesthesiology and Intensive Care Rome, I, Italy, 00161 Collapse << |
NCT00370253 | Hepatorenal Syndrome | Phase 3 | Completed | - | Italy ... more >> San Giovanni Battista Hospital Turin, Italy, 10126 Collapse << |
NCT00115947 | Cirrhosis Asc... more >>ites Collapse << | Phase 2 Phase 3 | Completed | - | Denmark ... more >> Hvidovre Hospital Copenhagen, Hvidovre, Denmark, 2650 Collapse << |
NCT01649037 | Hepatorenal Syndrome | Not Applicable | Withdrawn(lack of funds) | June 2015 | India ... more >> Institute of Liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT00534677 | Portal Hypertension ... more >> Cirrhosis Hematemesis Melena Collapse << | Phase 4 | Completed | - | Pakistan ... more >> The Aga Khan University Hospital Karachi, Sindh, Pakistan, 74800 Collapse << |
NCT00287664 | Cirrhosis Hep... more >>atorenal Syndrome Collapse << | Phase 4 | Suspended(because in a prelimi... more >>nary analysis we would need 1000 patients per group to achieve significative differences in the main end point.) Collapse << | - | Spain ... more >> Hospital Clinic Barcelona, Spain, 08036 Collapse << |
NCT02311608 | - | - | Unknown | June 2016 | China, Shanghai ... more >> Zhongshan Hospital Recruiting Shanghai, Shanghai, China, 200032 Contact: Bing Li, Doctor 86-18021057696 07301010228@fudan.edu.cn Collapse << |
NCT02757703 | Vasoconstrictor Choice on Acut... more >>e Variceal Bleeding Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Division of Gastroenterology, Department of Internal Medicine Kaohsiung, Taiwan, 81362 Collapse << |
NCT03483272 | - | - | Recruiting | January 2021 | Denmark ... more >> Hvidovre University Hospital Recruiting Hvidovre, Capital Region, Denmark, 2650 Contact: Flemming Bendtsen, Professor 0045 38623273 flemming.bendtsen@regionh.dk Contact: Karen V Danielsen, Ph.D-student 0045 22439449 karen.vagner.danielsen.02@regionh.dk Centre of Gastroenterology, Dept. of medicine. Hvidovre University Hospital Recruiting Hvidovre, Denmark, 2650 Contact: Flemming Bendtsen, Professor 38623273 flemming.bendtsen@regionh.dk Collapse << |
NCT00966355 | Variceal Bleeding, Cirrhosis | Phase 4 | Completed | - | Korea, Republic of ... more >> Korea University Anam Hospital Seoul, Korea, Republic of, 136-705 Collapse << |
NCT00966355 | - | - | Completed | - | - |
NCT01335516 | - | - | Completed | - | Romania ... more >> Emergency County Hospital - Surgery Clinic No.1 Târgu Mureş, Mureş, Romania Collapse << |
NCT03144713 | Cirrhosis | Not Applicable | Completed | - | India ... more >> Institute of Liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT02573727 | Acute on Chronic Liver Failure | Not Applicable | Completed | - | India ... more >> Institute of liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT00742690 | Cirrhosis Typ... more >>e 1 Hepatorenal Syndrome Collapse << | Phase 2 Phase 3 | Unknown | March 2015 | Italy ... more >> Liver Unit, General Hospital Recruiting Padova, Italy, 35100 Sub-Investigator: Giulio Maresio, MD Collapse << |
NCT01271114 | Septic Shock ... more >>Sepsis-associated Hypotension Collapse << | Phase 3 | Terminated(Low recruitment rat... more >>e) Collapse << | - | Spain ... more >> Hospital General de Ciudad Real Ciudad Real, Spain, 13005 Collapse << |
NCT00742339 | Cirrhosis Hep... more >>atorenal Syndrome Collapse << | Phase 2 Phase 3 | Terminated(Decision of indepen... more >>dent monitoring committee Risk of non-response to treatment significantly higher in midodrine group than in terlipressin group.) Collapse << | - | Italy ... more >> Dept. of Clinical and Experimental Medicine, University of Padova Padova, Italy, 35100 Collapse << |
NCT01697410 | Septic Shock | Not Applicable | Unknown | January 2016 | China, Guangdong ... more >> Surgical intensive care unit, 1st affiliated hospital of Sun Yat-sen university Recruiting Guangzhou, Guangdong, China, 510000 Contact: Guan Xiangdong, M.D. 862087555766-8456 carlg@163.net Principal Investigator: Guan Xiangdon, M.D Collapse << |
NCT03038503 | Septic Shock ... more >>Refractory Shock Collapse << | Phase 3 | Recruiting | December 2018 | Thailand ... more >> Ramathibodi hospital Recruiting Bangkok, Thailand, 066 Contact: munthana sundusadee, md 66639010178 opal_janeway@hotmail.com Collapse << |
NCT01836224 | Cirrhosis With Septic Shock | Not Applicable | Completed | - | India ... more >> Institute of liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT00369694 | Hemorrhage Es... more >>ophageal Varices Portal Hypertension Collapse << | Phase 4 | Completed | - | Pakistan ... more >> The Aga Khan University Hospital Karachi, Sindh, Pakistan, 74800 Collapse << |
NCT02306239 | Terlipressin ... more >>Septic Shock Collapse << | Not Applicable | Unknown | - | China, Guangdong ... more >> the First Affiliated Hospital of Sumyetsan University Recruiting Guangzhou, Guangdong, China, 510080 Contact: liu zimeng, doctor 020 ext 87755766 sumslzm@163.com Contact: zhang xuyu, doctor 020 ext 87755766 sumsxyz@163.com Collapse << |
NCT01932151 | Hepatorenal Syndrome | Not Applicable | Completed | - | Spain ... more >> Hospital Clinic de Barcelona Barcelona, Spain, 08036 Collapse << |
NCT00089570 | Hepatorenal Syndrome | Phase 3 | Completed | - | - |
NCT00986817 | Cirrhosis | Phase 3 | Completed | - | France ... more >> CARBONELL Nicolas Paris, France, 75012 Collapse << |
NCT01530711 | Cirrhosis Hep... more >>atorenal Syndrome Type I Collapse << | Phase 4 | Unknown | December 2016 | Spain ... more >> Corporació Sanitària Parc Taulí Sabadell, Barcelona, Spain, 08208 Hospital Moisés Broggi Sant Joan Despí, Barcelona, Spain, 08970 Hospital Clinic i Provincial de Barcelona Barcelona, Spain, 08036 Hospital del Mar Barcelona, Spain, 08036 Hospital Vall d´Hebron Barcelona, Spain, 08036 Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08041 Collapse << |
NCT00628160 | Liver Cirrhosis ... more >> Septic Shock Collapse << | Phase 2 Phase 3 | Completed | - | Spain ... more >> Hospital Clinic Barcelona Barcelona, Catalonia, Spain, 08036 Collapse << |
NCT01143246 | HRS | Phase 3 | Completed | - | - |
NCT02368249 | Kidney Failure | Phase 2 | Withdrawn(no focus on this top... more >>ic) Collapse << | February 2025 | Switzerland ... more >> Department of Visceral and Transplantation Surgery of the University Hospital of Zurich Zurich, Switzerland, 8091 Collapse << |
NCT01921985 | Liver Resection ... more >> Liver Failure Collapse << | Phase 2 | Terminated(Interim analysis re... more >>vealed that no statistical difference will be identified after inclusion of the patient cohort as foreseen in the sample size calculation) Collapse << | - | Switzerland ... more >> Dep. of Visceral Surgery, University Hospital Berne Berne, Switzerland, 3010 Collapse << |
NCT02489864 | Hepatorenal Syndrome | Phase 4 | Unknown | December 2017 | China, Guangdong ... more >> The Third Affiliated Hospital of Sun Yat-Sen University Recruiting Guangzhou, Guangdong, China, 510630 Contact: Chan Xie, Dr. 8602085252372 happyxiechan@hotmail.com Collapse << |
NCT02770716 | Hepatorenal Syndrome | Phase 3 | Recruiting | November 2019 | - |
NCT01637454 | Safety and Efficacy of Terlipr... more >>essin and Noradrenaline and Predictive Factors of Response in Type 2 HRS Collapse << | Phase 3 | Completed | - | India ... more >> Postgraduate Institute of Medical Education and Research Chandigarh Chandigarh, India, 160012 Collapse << |
NCT03352349 | Portal Vein Pressure | Phase 2 | Recruiting | December 30, 2018 | China, Shanghai ... more >> Zhongshan Hospital Recruiting Shanghai, Shanghai, China, 200032 Contact: Hui-Chuan Sun, MD&PhD Collapse << |
NCT00793559 | Septic Shock | Phase 2 | Unknown | July 2009 | Israel ... more >> Asaf Harofeh MC Not yet recruiting Zrifin, Israel, 70300 Collapse << |
NCT03336814 | Septic Shock | Phase 4 | Recruiting | June 1, 2019 | France ... more >> Assistance Publique - Hôpitaux de Marseille Recruiting Marseille Cedex 05, France, 13354 Contact: Duclos Gary gary.duclos@ap-hm.fr Collapse << |
NCT02119884 | Gastric and Esophageal Varices | Phase 4 | Completed | - | China, Shanghai ... more >> 180 Fenglin Road Shanghai, Shanghai, China, 200032 Collapse << |
NCT03395574 | Terlipressin Adverse Reaction ... more >> Liver Transplantation Collapse << | Phase 2 | Recruiting | July 2018 | Egypt ... more >> Kasr Alainy Hospital , Faculty of Medicine Recruiting Cairo, Egypt Contact: mohamed elayashy mohamed ahmed hassan, M.D 00201001833155 mohamedelayashy@kasralainy.edu.eg Collapse << |
NCT02695862 | Acute Variceal Bleeding | Not Applicable | Completed | - | India ... more >> Institute of liver and Biliary Sciences New Delhi, Delhi, India, 110070 Collapse << |
NCT03584087 | Acute Variceal Haemorrhage | Phase 4 | Recruiting | March 31, 2019 | India ... more >> Post Graduate Institute of Medical Education and Research Recruiting Chandigarh, India, 160012 Contact: Deba P Dhibar, MD +919530881462 drdeba_prasad@yahoo.co.in Collapse << |
NCT02970175 | Bronchial Endoscopy | Phase 3 | Recruiting | February 2020 | France ... more >> Rouen University Hospital Recruiting Rouen, France Contact: Mathieu SALAUN, MD Principal Investigator: Mathieu SALAUN, MD Sub-Investigator: Luc THIBERVILLE, Pr Collapse << |
NCT03477461 | - | - | Completed | - | - |
NCT03608514 | Resolution of Septic Shock Wit... more >>h Terlipressin Collapse << | Phase 2 Phase 3 | Recruiting | December 2020 | Egypt ... more >> NHTMRI Recruiting Cairo, Egypt, 11441 Contact: Eman El-Desoki, Ph D 01227409501 eman18350@gmail.com Collapse << |
NCT03572088 | Terlipressin ... more >>Blood Loss Collapse << | Phase 2 | Completed | - | - |
NCT02718599 | Hemodynamics, Liver, Terlipres... more >>sin Collapse << | Phase 2 | Completed | - | Egypt ... more >> Assiut University hospital Assiut, Asyut Governorate, Egypt, 11111 Collapse << |
NCT02059460 | Acute Kidney Injury ... more >> Liver Transplantation Terlipressin NGAL Collapse << | Phase 4 | Completed | - | Egypt ... more >> National Liver Institute Shebeen Alkom, Menoufiya, Egypt, 32511 Collapse << |
NCT03130127 | Liver Cirrhosis ... more >> Portal Hypertension Variceal Hemorrhage Bleeding Esophageal and Gastric Varices Collapse << | Not Applicable | Not yet recruiting | December 1, 2020 | - |
NCT02588716 | Hepatectomy, Surgical Blood Lo... more >>ss, Terlipressin Collapse << | Phase 2 | Completed | - | Egypt ... more >> Assiut University hospital Assiut, Asyut Governorate, Egypt, 11111 Collapse << |
NCT03107091 | Cirrhosis Asc... more >>ites Hepatic Collapse << | Phase 2 | Recruiting | June 2018 | United States, Virginia ... more >> Hunter Holmes McGuire VA Medical Center Recruiting Richmond, Virginia, United States, 23239 Contact: Edith Gavis, RN 804-675-5000 ext 5199 edith.gavis@va.gov Collapse << |
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