CAS No.: 312917-14-9
TCS JNK 5a Catalog No. CSN15772
Synonyms: JNK Inhibitor IX;c-Jun N-terminal Kinase Inhibitor IX;SC-202671
JNK Inhibitor IX can selectively inhibit JNK2 and JNK3 through targeting the ATP binding site with pIC50 of 6.5 and 6.7, respectively.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
靶点 JNK2
pIC50:6.5JNK3
pIC50:6.7- 描述
- 作用机制
- 参考文献
- [1] Rudolf E, Cervinka M. Trivalent chromium activates Rac-1 and Src and induces switch in the cell death mode in human dermal fibroblasts. Toxicol Lett. 2009 Aug 10;188(3):236-42.
- [2] Angell RM, Atkinson FL, et al. N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1296-301.
- [3] Angell RM, Atkinson FL, Brown MJ, et al. N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3. Bioorg Med Chem Lett. 2007;17(5):1296-1301. doi:10.1016/j.bmcl.2006.12.003
- [4] Rudolf E, Cervinka M. Trivalent chromium activates Rac-1 and Src and induces switch in the cell death mode in human dermal fibroblasts. Toxicol Lett. 2009;188(3):236-242. doi:10.1016/j.toxlet.2009.04.019
- [5] Mancini M, Veljkovic N, Corradi V, et al. 14-3-3 ligand prevents nuclear import of c-ABL protein in chronic myeloid leukemia. Traffic. 2009;10(6):637-647. doi:10.1111/j.1600-0854.2009.00897.x
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 312917-14-9 | 储存条件 |
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| 分子式 | C20H16N2OS | 运输 | 蓝冰 | |||||||
| 分子量 | 332.42 | 别名 | JNK Inhibitor IX;c-Jun N-terminal Kinase Inhibitor IX;SC-202671 | |||||||
| 溶解度 |
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动物实验配方 |
