CAS No.: 1257426-19-9
TBA-354 Catalog No. CSN15850
Synonyms: SN-31354
TBA-354 is a potent anti-tuberculosis compound and maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02606214 Tuberculosis Phase 1 Terminated(Clinical Hold from ... more >>FDA) Collapse << - - NCT02288481 Tuberculosis Phase 1 Completed - United States, Nebraska ... more >> Celerion Lincoln, Nebraska, United States, 68502 Collapse << - 参考文献
- [1] Upton AM, Cho S, et al. In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2015 Jan;59(1):136-44.
- [2] Tasneen R, Williams K, et al. Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis. Antimicrob Agents Chemother. 2015 Jan;59(1):129-35.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1257426-19-9 | 储存条件 |
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| 分子式 | C19H15F3N4O5 | 运输 | 蓝冰 | |
| 分子量 | 436.34 | 别名 | SN-31354 |
