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CAS No.: 254964-60-8
Synonyms: ABR-215050;他喹莫德
Tasquinimod allosterically inhibits HDAC4 signalling with antiangiogenic and antineoplastic activities. It is a quinoline-3-carboxamide linomide analogue.
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生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00560482 | Prostate Cancer | Phase 2 | Completed | - | - |
NCT01743469 | Advanced or Metastatic Hepatoc... more >>ellular Cancer Advanced or Metastatic Ovarian Cancer Metastatic Renal Cell Cancer Advanced or Metastatic Gastric Carcinoma Collapse << | Phase 2 | Completed | - | Belgium ... more >> Antwerp University Hospital, Wilrijkstraat 10 Edegem, Belgium, 2650 Ghent University Hospital, 1K12 IE, De Pintelaan 185 Gent, Belgium, 9000 Leuven cancer institute (LKI), Herestraat Leuven, Belgium, 3000 Canada, Ontario Juravinski Cancer Centre, 699 Concession St Hamilton, Ontario, Canada, L8V 5C2 London Health Sciences Center, 790 Commissoners Road East London, Ontario, Canada, N6A 4L6 Sunnybrook, 2075 Bayview Avenue, Suite T2049 Toronto, Ontario, Canada, M4N 3M5 Princess Margaret, 610 University Avenue Toronto, Ontario, Canada, M5G 2M9 France Hospital Beaujon, 100 Blvd du Général Leclerc Clichy, France, 92110 Centre Oscar Lambret, 3 rue Frédéric Combemale Lille cedex, France, 59020 Bureau d'Etudes Cliniques du Centre Léon Bérard, 28, rue Laennec Lyon, France, 69008 Hospital Saint-Antoine, 184 rue du Faubourg St Antoine Paris, France, 75012 Hopital Europeen Georges-Pompidou, AP-HP, 20 Rue Leblanc Paris, France, 75015 Centre Eugene Marquis, Avenue bataille Flandres Dunkerque Rennes cedex, France, 35042 Centre René Gauducheau, Boulevard Jacques Monod Saint Herblain, France, 44805 Institute Gustave-Roussy, 114 rue Edouard Vaillant Villejuif, France, 94805 Spain Hospital del mar, Paseo Maritimo 25-29 Barcelona, Spain, 08003 Hospital Gregorio Marañon, Dr. Esquerdo, 44-46 Madrid, Spain, 28007 MD Anderson Cancer Centre, Ctra. Colmenar Viejo Km. 9 100, Madrid, Spain, 28034 United Kingdom Beatson West of Scotland Cancer Centre, 1053 Great Western Road Glasgow, United Kingdom, G12 0YN Leicester General Hospital, Gwndolen Road Leicester, United Kingdom, LE5 4PW The Royal Marsden Hospital, Downs Rd, Sutton London, United Kingdom, SM2 5PT The Christie Hospital, Wilmslow Road, Withington Manchester, United Kingdom, M20 4BX Freeman Hospital, Freeman Road, High Heaton Newcastle-upon-Tyne, United Kingdom, NE7 7DN Southampton General Hospital, Tremona Road, Shirley Southampton, United Kingdom, SO16 6YD Collapse << |
NCT02057666 | Asian Chemo-naïve Patients Wit... more >>h Metastatic Castrate-resistant Prostate Cancer Collapse << | Phase 3 | Terminated(Development of tasq... more >>uinimod in prostate cancer discontinued) Collapse << | - | China ... more >> Beijing, China Changsha, China Chengdu, China Chongqing, China Guangzhou, China Hangzhou, China Nanchang, China Nanjing, China Shanghai, China Shantou, China Shenyang, China Soochow, China Tianjin, China Wenzhou, China Wuhan, China Korea, Republic of Cheongju, Korea, Republic of Seoul, Korea, Republic of Taiwan Taichung, Taiwan Taipei, Taiwan Collapse << |
实验方案
技术信息
CAS号 | 254964-60-8 | 储存条件 |
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分子式 | C20H17F3N2O4 | 运输 | 蓝冰 | |||||||||||
分子量 | 406.36 | 别名 | ABR-215050;他喹莫德 | |||||||||||
溶解度 |
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动物实验配方 |
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