CAS No.: 174634-08-3
TAS-103 Catalog No. CSN18018
Synonyms: BMS-247615
TAS-103 is a dual inhibitor of topoisomerase-I (topo-I) and topoisomerase-II (topoII).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Yoshida M, Kabe Y, et al. A new mechanism of 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one dihydrochloride (TAS-103) action discovered by target screening with drug-immobilized affinity beads. Mol Pharmacol. 2008 Mar;73(3):987-94.
- [2] Parajuli P, Yano S, et al. Therapeutic efficacy of a new topoisomerase I and II inhibitor TAS-103, against both P-glycoprotein-expressing and -nonexpressing drug-resistant human small-cell lung cancer. Oncol Res. 1999;11(5):219-24.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 174634-08-3 | 储存条件 |
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| 分子式 | C20H19N3O2 | 运输 | 蓝冰 | |
| 分子量 | 333.38 | 别名 | BMS-247615 |
