CAS No.: 85375-15-1
SKF89976A HCl Catalog No. CSN17061
Synonyms: d,l-SKF89976A hydrochloride;SKF-89976A
SKF-89976A HCl is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Jinzenji A, Sogawa C, et al. Antiallodynic action of 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methyoxyphenyl)-4-piperidinol(NNC05-2090), a betaine/GABA transporter inhibitor. J Pharmacol Sci.2014;125(2):217-26.
- [2] Kreitzer MA, Andersen KA, et al. Glutamate modulation of GABA transport in retinal horizontal cells of the skate. J Physiol. 2003 Feb 1;546(Pt 3):717-31.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 85375-15-1 | 储存条件 |
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| 分子式 | C22H26ClNO2 | 运输 | 蓝冰 | |||
| 分子量 | 371.90 | 别名 | d,l-SKF89976A hydrochloride;SKF-89976A | |||
| 溶解度 |
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动物实验配方 |
