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CAS No.: 866460-33-5

Setipiprant Catalog No. CSN16883

Synonyms: ACT-129968;KYTH-105

Setipiprant is an orally available, selective CRTH2 antagonist.

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纯度 & 质量文件批次:

靶点选择性

生物活性

描述Setipiprant is an orally available, selective CRTH2 antagonist.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01484119	Seasonal Allergic Rhinitis	Phase 3	Completed	-	United States, Texas ... more >> Clinical Investigative Site 7905 Austin, Texas, United States, 78731 Clinical Investigative Site 7907 Kerrville, Texas, United States, 78028 Clinical Investigative Site 7903 New Braunfels, Texas, United States, 78130 Clinical Investigative Site 7901 San Antonio, Texas, United States, 78229 Clinical Investigative Site 7902 San Antonio, Texas, United States, 78229 Clinical Investigative Site 7904 San Antonio, Texas, United States, 78229 Clinical Investigative Site 7906 San Antonio, Texas, United States, 78229 Collapse <<
NCT02381496	Healthy	Phase 1	Completed	-	-
NCT01225315	Asthma	Phase 2	Completed	-	-

更多
参考文献

[1] Gehin M, Sidharta PN, et al. Pharmacokinetic interactions between simvastatin and setipiprant, a CRTH2 antagonist. Eur J Clin Pharmacol. 2015 Jan;71(1):15-23.
[2] Hoch M, Wank J, et al. Disposition and metabolism of setipiprant, a selective oral CRTH2 antagonist, in humans. Drugs R D. 2013 Dec;13(4):253-69.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.4850 mL
- 12.4249 mL
- 24.8498 mL
- 5 mM
- 0.4970 mL
- 2.4850 mL
- 4.9700 mL
- 10 mM
- 0.2485 mL
- 1.2425 mL
- 2.4850 mL

技术信息

CAS号	866460-33-5		储存条件	粉末 Sealed in dry,Room Temperature 液体 -20°C:3-6 月 -80°C:12月
分子式	C24H19FN2O3		运输	蓝冰
分子量	402.42		别名	ACT-129968;KYTH-105

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01484119	Seasonal Allergic Rhinitis	Phase 3	Completed	-	United States, Texas ... more >> Clinical Investigative Site 7905 Austin, Texas, United States, 78731 Clinical Investigative Site 7907 Kerrville, Texas, United States, 78028 Clinical Investigative Site 7903 New Braunfels, Texas, United States, 78130 Clinical Investigative Site 7901 San Antonio, Texas, United States, 78229 Clinical Investigative Site 7902 San Antonio, Texas, United States, 78229 Clinical Investigative Site 7904 San Antonio, Texas, United States, 78229 Clinical Investigative Site 7906 San Antonio, Texas, United States, 78229 Collapse <<
NCT02381496	Healthy	Phase 1	Completed	-	-
NCT01225315	Asthma	Phase 2	Completed	-	-
NCT02781311	Alopecia	Phase 2	Completed	-	United States, Arkansas ... more >> Burke Pharmaceutical Research Hot Springs, Arkansas, United States, 71913 Petrus Center for Aesthetic Surgery & Hair Transplantation Little Rock, Arkansas, United States, 72205 United States, California Therapeutics Clinical Research San Diego, California, United States, 92123 Synexus USA Santa Rosa, California, United States, 95405 United States, Illinois Arano, LLC Chicago, Illinois, United States, 60611 United States, Kansas Heartland Research Associates, LLC Wichita, Kansas, United States, 67207 United States, Michigan Michigan Center for Skin Care Research Clinton Township, Michigan, United States, 48038 United States, Minnesota Minnesota Clinical Study Center Fridley, Minnesota, United States, 55432 University of Minnesota Minneapolis, Minnesota, United States, 55455 United States, North Carolina Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 United States, Ohio Cleveland Clinic Cleveland, Ohio, United States, 44195 United States, Oregon NW Dermatology & Research Center Portland, Oregon, United States, 97210 Oregon Medical Research Center Portland, Oregon, United States, 97223 United States, Pennsylvania Penn State Hershey Medical Center Hershey, Pennsylvania, United States, 17033 United States, South Carolina Synexus USA Greer, South Carolina, United States, 29650 United States, Texas DermResearch, Inc Austin, Texas, United States, 78759 Suzzane Bruce and Associates P.A., The Center for Skin Research Katy, Texas, United States, 77494 United States, Virginia The Education & Research Foundation Lynchburg, Virginia, United States, 24501 Collapse <<

总药量计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 动物数量只每天给药次给药天

需要的总药量：mg

工作液计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 给药体积μL

您需要配制的工作液浓度为：mg/mL

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