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CAS No.: 27740-01-8

Scutellarin/野黄芩苷 Catalog No. CSN10165

Synonyms: Breviscapine;Breviscapin;Scutellarein-7-glucuronide

Scutellarin is an active flavonoid that shows anti-tumor activity and anti-proteasome action. It can be isolated from the root of Scutellaria baicalensis Georgi.

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技术信息

生物活性

描述Scutellarin is the major active component extracted from Erigeron breviscapus with antioxidant and anti-inflammation properties. Scutellarin can regulate the expression of GFAP, Notch-1 signaling, and nestin along with that of proinflammatory mediators in reactive astrocytes in ischemic injury^[3]. Moreover, Scutellarin-treated breast carcinoma MCF-7 cells had significantly inhibited growth and induced apoptosis^[4]. Scutellarin(5 mg/kg/day) can protect against DOX (doxorubicin)-induced acute cardiotoxicity through its antioxidant activity and alterations of heart concentrations^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.1628 mL
- 10.8141 mL
- 21.6282 mL
- 5 mM
- 0.4326 mL
- 2.1628 mL
- 4.3256 mL
- 10 mM
- 0.2163 mL
- 1.0814 mL
- 2.1628 mL

技术信息

CAS号

27740-01-8

储存条件

粉末: Sealed in dry,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C21H18O12

运输

蓝冰

分子量

462.36

别名

Breviscapine;Breviscapin;Scutellarein-7-glucuronide;Scutellarein 7-b-D-Glucuronide;Scutellarein 7-O-β-D-glucuronide;野黄芩苷

溶解度

DMSO	215.0 mg/mL (465.0 mM)
Water	insoluble

动物实验配方

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