CAS No.: 1533426-72-0
SCR7 Catalog No. CSN15756
SCR7 is an inhibitor of DNA Ligase IV, it inhibits joining of DSBs in cell-free repair system and inhibits NHEJ (nonhomologous end-joining) in a Ligase IV-dependent manner within cells, and activates the intrinsic apoptotic pathway.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Lin C, Li H, et al. Increasing the Efficiency of CRISPR/Cas9-mediated Precise Genome Editing of HSV-1 Virus in Human Cells. Sci Rep. 2016 Oct 7;6:34531.
- [2] Srivastava M, Nambiar M, et al. An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression. Cell. 2012 Dec 21;151(7):1474-87.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1533426-72-0 | 储存条件 |
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| 分子式 | C18H14N4OS | 运输 | 蓝冰 | |
| 分子量 | 334.40 | 别名 |
