CAS No.: 215802-15-6
SB269652 Catalog No. CSN18110
Synonyms: SB-269,652
SB-269652 is the first drug-like allosteric modulator of the dopamine D2 receptor (D2R) and a chemical probe that can differentiate D2R monomers from dimers or oligomers depending on the observed pharmacology.
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Lane JR, Donthamsetti P, et al. A new mechanism of allostery in a G protein-coupled receptor dimer. Nat Chem Biol. 2014 Sep;10(9):745-52.
- [2] Silvano E, Millan MJ, et al. The tetrahydroisoquinoline derivative SB269,652 is an allosteric antagonist at dopamine D3 and D2 receptors. Mol Pharmacol. 2010 Nov;78(5):925-34.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 215802-15-6 | 储存条件 |
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| 分子式 | C27H30N4O | 运输 | 蓝冰 | |
| 分子量 | 426.55 | 别名 | SB-269,652 |
