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CAS No.: 1448584-12-0
Synonyms: BCL-201;Servier-1
S55746 is a potent and selective inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities.
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生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02603445 | Follicular Lymphoma, Mantle Ce... more >>ll Lymphoma Collapse << | Phase 1 | Completed | - | United States, New York ... more >> Novartis Investigative Site New York, New York, United States, 10017 United States, Texas Novartis Investigative Site Houston, Texas, United States, 77030 Austria Novartis Investigative Site Salzburg, Austria, 5020 France Novartis Investigative Site Pierre-Benite Cedex, France, 69495 Novartis Investigative Site Toulouse Cedex 9, France, 31059 Germany Novartis Investigative Site Freiburg, Germany, 79106 Novartis Investigative Site Mainz, Germany, 55131 Collapse << |
NCT02920697 | Chronic Lymphocytic Leukaemia ... more >>(CLL) B-Cell Non-Hodgkin Lymphoma (NHL) Multiple Myeloma (MM) Collapse << | Phase 1 | Completed | - | Australia ... more >> The Alfred Hospital Malignant Haematology & Stem Cell Transplantation Services Melbourne, Australia, 3004 France Hopital Claude Huriez Lille, France CHU de Nantes Nantes, France Centre hospitalier Lyon Sud Pierre-Bénite, France Gustave Roussy Villejuif, France Germany Universitätsklinikum Carl Gustav Carus Dresden, Germany Städtisches Klinikum Schwabing Munich, Germany Universitätsklinikum Ulm Ulm, Germany Hungary National Oncology Institute Budapest, Hungary CRU Hungary Kft Miskolc, Hungary Korea, Republic of Severance Hospital Seoul, Korea, Republic of St. Mary's Hospital Seoul, Korea, Republic of Poland Warsaw Institute of Oncology Warsaw, Poland Warsaw Medical University Warsaw, Poland Singapore National Cancer Center (NCC) Singapore, Singapore National University Cancer Institute Singapore Singapore, Singapore United Kingdom University College London Hospitals London, United Kingdom Freeman Hospital Newcastle, United Kingdom Collapse << |
实验方案
技术信息
CAS号 | 1448584-12-0 | 储存条件 |
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分子式 | C43H42N4O6 | 运输 | 蓝冰 | |||||
分子量 | 710.82 | 别名 | BCL-201;Servier-1 | |||||
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动物实验配方 |