CAS No.: 168986-60-5
RS 67333 HCl Catalog No. CSN20353
RS-67333 HCl is a potent and highly selective 5-HT4 partial agonist, with pKi values of 8.7 at 5-HT4 sites in guinea pig striatum and > 6 at various other receptors, including 5-HT1A, 1D, 2A, 2C, D1, D2 and M1-3. It is also active in vivo, with an intrinsic activity relative to 5-HT of 0.5.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Giannoni P, Gaven F, et al. Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease. Front Aging Neurosci. 2013 Dec 24;5:96.
- [2] Lelong V, Dauphin F, Boulouard M. RS 67333 and D-cycloserine accelerate learning acquisition in the rat. Neuropharmacology. 2001 Sep;41(4):517-22.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 168986-60-5 | 储存条件 |
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| 分子式 | C19H30Cl2N2O2 | 运输 | 蓝冰 | |||||
| 分子量 | 389.36 | 别名 | ||||||
| 溶解度 |
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动物实验配方 |
