CAS No.: 161582-11-2
Ro 48-8071 Catalog No. CSN17952
Ro 48-8071 is an inhibitor of OSC (Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Liang Y, Mafuvadze B, et al. Cholesterol biosynthesis inhibitor RO 48-8071 suppresses growth of hormone-dependent and castration-resistant prostate cancer cells. Onco Targets Ther. 2016 May 30;9:3223-32.
- [2] Morand OH, Aebi JD, et al. Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin. J Lipid Res. 1997 Feb;38(2):373-90.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 161582-11-2 | 储存条件 |
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| 分子式 | C23H27BrFNO2 | 运输 | 蓝冰 | |
| 分子量 | 448.37 | 别名 |
