CAS No.: 1342278-01-6
RKI-1447 Catalog No. CSN15904
Synonyms: Rki-1447
RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, and has anti-invasive and antitumor activities.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Patel RA, Forinash KD, et al. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. Cancer Res. 2012 Oct 1;72(19):5025-34.
- [2] Pireddu R, Forinash KD, et al. Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2). Medchemcomm. 2012 Jun 1;3(6):699-709. Epub 2012 Jan 27.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1342278-01-6 | 储存条件 |
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| 分子式 | C16H14N4O2S | 运输 | 蓝冰 | |||||||
| 分子量 | 326.37 | 别名 | Rki-1447 | |||||||
| 溶解度 |
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动物实验配方 |
