CAS No.: 147254-64-6
Ranirestat Catalog No. CSN17888
Synonyms: AS-3201;SX-3201
Ranirestat is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00927914 Mild to Moderate Diabetic Sens... more >>orimotor Polyneuropathy. Collapse << Phase 2 Phase 3 Completed - United States, Maryland ... more >> The Johns Hopkins Hospital Baltimore, Maryland, United States, 21231 Collapse << NCT00101426 Diabetic Neuropathy Phase 3 Completed - Canada, Ontario ... more >> Toronto General Hospital, University Health Network Toronto, Ontario, Canada, M5G 2C4 Collapse << - 参考文献
- [1] Matsumoto T, Ono Y, et al. Improvement of motor nerve conduction velocity in diabetic rats requires normalization of the polyol pathway metabolites flux. J Pharmacol Sci. 2009 Feb;109(2):203-10.
- [2] Kurono M, Fujii A, et al. Stereospecific recognition of a spirosuccinimide type aldose reductase inhibitor (AS-3201) by plasma proteins: a significant role of specific binding by serum albumin in the improved potency and stability. Biochem Pharmacol. 2006 Jan 12;71(3):338-53.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 147254-64-6 | 储存条件 |
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| 分子式 | C17H11BrFN3O4 | 运输 | 蓝冰 | |
| 分子量 | 420.19 | 别名 | AS-3201;SX-3201 |
