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CAS No.: 1234015-57-6
Synonyms: LY2606368 Mesylate Hydrate;LY2940930;LY-2606368
Prexasertib, also known as LY2606368, is a potent and selective Chk1/Chk2 inhibitor. Prexasertib increases the effectiveness of conventional therapy in B-/T- cell progenitor acute lymphoblastic leukemia. LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms. Treatment of cells with LY2606368 results in the rapid appearance of TUNEL and pH2AX-positive double-stranded DNA breaks in the S-phase cell population.
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技术信息
CAS号 | 1234015-57-6 | 储存条件 |
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分子式 | C19H25N7O6S | 运输 | 蓝冰 | |
分子量 | 479.51 | 别名 | LY2606368 Mesylate Hydrate;LY2940930;LY-2606368 |
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