CAS No.: 55916-51-3
Polyphyllin VI/重楼皂苷VI Catalog No. CSN19990
Synonyms: Chonglou Saponin Ⅵ;重楼皂苷VI;重楼皂苷Ⅵ
Polyphyllin VI, a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Zhao Y, Zhang J, et al. Discrimination of wild Paris based on near infrared spectroscopy and high performance liquid chromatography combined with multivariate analysis. PLoS One. 2014 Feb 18;9(2):e89100.
- [2] Yin X, Qu C, et al. Simultaneous determination and pharmacokinetic study of polyphyllin I, polyphyllin II, polyphyllin VI and polyphyllin VII in beagle dog plasma after oral administration of Rhizoma Paridis extracts by LC-MS-MS. Biomed Chromatogr. 2013 Mar;27(3):343-8.
- [3] Teng JF, Mei QB, Zhou XG, Tang Y, Xiong R, Qiu WQ, Pan R, Law BY, Wong VK, Yu CL, Long HA, Xiao XL, Zhang F, Wu JM, Qin DL, Wu AG. Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer. Cancers (Basel). 2020 Jan 13;12(1):193
- [4] Yuan YL, Jiang N, Li ZY, Song ZZ, Yang ZH, Xue WH, Zhang XJ, Du Y. Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation. Drug Des Devel Ther. 2019 Aug 28;13:3091-3103
- [5] Liu W, Chai Y, Hu L, Wang J, Pan X, Yuan H, Zhao Z, Song Y, Zhang Y. Polyphyllin VI Induces Apoptosis and Autophagy via Reactive Oxygen Species Mediated JNK and P38 Activation in Glioma. Onco Targets Ther. 2020 Mar 13;13:2275-2288
- [6] Liu Y, Dong X, Wang W, You L, Yin X, Yang C, Sai N, Leng X, Ni J. Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway. Toxins (Basel). 2018 May 15;10(5):201
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 55916-51-3 | 储存条件 |
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| 分子式 | C39H62O13 | 运输 | 蓝冰 | |||||
| 分子量 | 738.90 | 别名 | Chonglou Saponin Ⅵ;重楼皂苷VI;重楼皂苷Ⅵ | |||||
| 溶解度 |
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动物实验配方 |
