CAS No.: 344458-19-1
PJ34 Catalog No. CSN17163
PJ34 is a potent specific inhibitor of PARPl/2 with IC50 of 110 nM and 86 nM, respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Haddad M, Rhinn H, et al. Anti-inflammatory effects of PJ34, a poly(ADP-ribose) polymerase inhibitor, in transient focal cerebral ischemia in mice. Br J Pharmacol. 2006 Sep;149(1):23-30. Epub 2006 Jul 24.
- [2] Iwashita A, Tojo N, et al. A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl] -4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia. J Pharmacol Exp Ther. 2004 Aug;310(2):425-36.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 344458-19-1 | 储存条件 |
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| 分子式 | C17H17N3O2 | 运输 | 蓝冰 | |
| 分子量 | 295.34 | 别名 |
