CAS No.: 2070015-24-4
Pimelic Diphenylamide 106 (analog) Catalog No. CSN18939
Synonyms: RGFA-8 analog;TC-H 106 analog
Pimelic diphenylamide 106 Analog is an analog of Pimelic Diphenylamide 106 with unknown biological activity. Pimelic Diphenylamide 106 is a class I HDAC inhibitor, demonstrating no activity against class II HDACs. 106 is a slow, tight-binding inhibitor of HDACs 1, 2, and 3 with preference toward HDAC3 with Ki of approximately 14 nm, 15 times lower than the Ki for HDAC1.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Chou CJ, Herman D, et al. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. J Biol Chem. 2008 Dec 19;283(51):35402-9.
- [2] Xu C, Soragni E, et al. Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chem Biol. 2009 Sep 25;16(9):980-9.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 2070015-24-4 | 储存条件 |
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| 分子式 | C21H27N3O2 | 运输 | 蓝冰 | |
| 分子量 | 353.46 | 别名 | RGFA-8 analog;TC-H 106 analog |
