CAS No.: 1586767-92-1
PHA-543613 hydrochloride Catalog No. CSN20198
Synonyms: PHA 543613 HCl
PHA-543613 HCl acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Foucault-Fruchard L, Domene A, et al. Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in vivo excitotoxic adult rat model. Neuroscience. 2017 May 18;356:52-63.
- [2] Macpherson A, Zoheir N, et al. The alpha 7 nicotinic receptor agonist PHA-543613 hydrochloride inhibits Porphyromonas gingivalis-induced expression of interleukin-8 by oral keratinocytes. Inflamm Res. 2014 Jul;63(7):557-68.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1586767-92-1 | 储存条件 |
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| 分子式 | C15H18ClN3O2 | 运输 | 蓝冰 | |
| 分子量 | 307.78 | 别名 | PHA 543613 HCl |
