CAS No.: 2070015-01-7
PF-8380 HCl Catalog No. CSN19047
Synonyms: 3,5-Dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate hydrochloride
PF-8380 HCl is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Bhave SR, Dadey DY, et al. Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines. Front Oncol. 2013 Sep 17;3:236.
- [2] Gierse J, Thorarensen A, et al. A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation. J Pharmacol Exp Ther. 2010 Jul;334(1):310-7.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 2070015-01-7 | 储存条件 |
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| 分子式 | C22H22Cl3N3O5 | 运输 | 蓝冰 | |
| 分子量 | 514.79 | 别名 | 3,5-Dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate hydrochloride |
