CAS No.: 1415562-83-2
PF-543 Citrate Catalog No. CSN17818
Synonyms: Sphingosine Kinase 1 Inhibitor II Citrate
PF-543 citrate is a cell-permeant inhibitor of SphK1 with a K (i) of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Wang J, Knapp S, et al. Crystal Structure of Sphingosine Kinase 1 with PF-543. ACS Med Chem Lett. 2014 Oct 27;5(12):1329-33.
- [2] Schnute ME, McReynolds MD, et al. Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1. Biochem J. 2012 May 15;444(1):79-88.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1415562-83-2 | 储存条件 |
|
|
| 分子式 | C33H39NO11S | 运输 | 蓝冰 | |
| 分子量 | 657.73 | 别名 | Sphingosine Kinase 1 Inhibitor II Citrate |
