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CAS No.: 26305-03-3
Synonyms: Pepsin Inhibitor S 735A;NSC-272671;Pepstatin A
Pepstatin A is a potent and specific aspartic protease inhibitor, also inhibits HIV replication.
生物活性
动物研究 | |
剂量 | Mice: 25 mg/kg - 200 mg/kg[3] (i.p.) |
给药途径 | i.p. |
实验方案
技术信息
CAS号 | 26305-03-3 | 储存条件 |
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分子式 | C34H63N5O9 | 运输 | 蓝冰 | |||||
分子量 | 685.89 | 别名 | Pepsin Inhibitor S 735A;NSC-272671;Pepstatin A;Pepstatinum;抑肽素;胃酶抑素A | |||||
溶解度 |
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动物实验配方 |
Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
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human MCF7 cells | - | Function assay | - | Inhibition of cathepsin D in human MCF7 cells by fluorescence assay, IC50=0.005 μM | 19715320 |
human MCF7 cells | - | Function assay | 1 h | Inhibition of cathepsin D in human MCF7 cells treated for 1 hr measured after washout and trypsin treatment by fluorescence assay, IC50=5 μM | 19715320 |
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