CAS No.: 941690-55-7
Pavinetant Catalog No. CSN19286
Synonyms: MLE-4901;AZD2624;AZD4901
MLE4901 is an antagonist of Neurokinin 3 Receptor and a potential drug for Polycystic ovary syndrome and menopausal hot flushes.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02865915 Polycystic Ovary Syndrome (PCO... more >>S) Collapse << Phase 2 Terminated(The risk/benefit pr... more >>ofile no longer indicated continued development.) Collapse << - - - 参考文献
- [1] Skorupskaite K, George JT, et al. Neurokinin 3Receptor Antagonism Reveals Roles for Neurokinin B in the Regulation of Gonadotropin Secretion and Hot Flashes in Postmenopausal Women. Neuroendocrinology. 2017 Apr 5.
- [2] Prague JK, Roberts RE, et al. Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet. 2017 May 6;389(10081):1809-1820.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 941690-55-7 | 储存条件 |
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| 分子式 | C26H25N3O3S | 运输 | 蓝冰 | |
| 分子量 | 459.56 | 别名 | MLE-4901;AZD2624;AZD4901;AZ-12472520;pavinetant |
