CAS No.: 1431698-10-0
OTSSP167 HCl Catalog No. CSN17849
Synonyms: OTS167 hydrochloride;MELK Inhibitor HCl;OTSSP167 (hydrochloride)
OTSSP167 HCl is a highly potent MELK inhibitor (IC50 = 0.41 nM) and inhibited the phosphorylation of PSMA1 (proteasome subunit alpha type 1) and DBNL (drebrin-like).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Ji W, Arnst C, et al. OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases. PLoS One. 2016 Apr 15;11(4):e0153518.
- [2] Chung S, Suzuki H, et al. Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer. Oncotarget. 2012 Dec;3(12):1629-40.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1431698-10-0 | 储存条件 |
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| 分子式 | C25H29Cl3N4O2 | 运输 | 蓝冰 | |
| 分子量 | 523.88 | 别名 | OTS167 hydrochloride;MELK Inhibitor HCl;OTSSP167 (hydrochloride);OTSSP-167;OTS-167;OTSSP167 HCl;OTS167 HCl |
