|(S)-2-(1-(2-苯基乙酰基)吡咯烷-2-甲酰胺基)乙酸乙酯|CsnPharm

CAS No.: 157115-85-0

Omberacetam Catalog No. CSN13580

Synonyms: GVS-111;SGS-111;N-Phenylacetyl-L-Prolylglycine ethyl ester

Noopept is a potent nootropic that improves cognitive ability.

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技术信息

生物活性

描述Noopept is a dipeptide analog of the standard cognition enhancer, piracetam. Noopept protects PC12 cell against deleterious actions of Aβ through inhibiting the oxidative damage and calcium overload as well as suppressing the mitochondrial apoptotic pathway. Moreover, neuroprotective properties of noopept likely include its ability to decrease tau phosphorylation and to restore the altered morphology of PC12 cells^[3]. Noopept added to the medium before or after glutamic acid improved neuronal survival in a concentration range of 10-11-10-5 M^[4]. Noopept increased the frequency of spontaneous calcium transients in neurons of CA1 radial layer in cultured rat hippocampal slices^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.1410 mL
- 15.7051 mL
- 31.4102 mL
- 5 mM
- 0.6282 mL
- 3.1410 mL
- 6.2820 mL
- 10 mM
- 0.3141 mL
- 1.5705 mL
- 3.1410 mL

技术信息

CAS号

157115-85-0

储存条件

粉末: Sealed in dry,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C17H22N2O4

运输

蓝冰

分子量

318.37

别名

GVS-111;SGS-111;N-Phenylacetyl-L-Prolylglycine ethyl ester;DVD-111;N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯

溶解度

DMSO	99.0 mg/mL (311.0 mM)

动物实验配方

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