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CAS No.: 24338-53-2

Nagilactone C Catalog No. CSN14246

Synonyms: Nagilactone-C

Nagilactone C, a natural product isolated and purified from the herbs of Podocarpus neriifolius, possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 mg/mL, respectively.

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技术信息

生物活性

描述Nagilactone C, a natural product isolated and purified from the herbs of Podocarpus neriifolius, possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 mg/mL, respectively. It is also a protein synthesis inhibitor which is specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation, and shows high insecticidal activity against second-instar nymphs of Eocanthecona furcellata.
参考文献

[1] Chan J, Khan SN, et al. Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles. RNA. 2004 Mar;10(3):528-43.
[2] Shrestha K, Banskota AH, et al. An antiproliferative norditerpene dilactone, Nagilactone C, from Podocarpus neriifolius. Phytomedicine. 2001 Nov;8(6):489-91.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.7596 mL
- 13.7981 mL
- 27.5961 mL
- 5 mM
- 0.5519 mL
- 2.7596 mL
- 5.5192 mL
- 10 mM
- 0.2760 mL
- 1.3798 mL
- 2.7596 mL

技术信息

CAS号	24338-53-2	储存条件	粉末液体 -20°C:3-6 月 -80°C:12月
分子式	C19H22O7	运输	蓝冰
分子量	362.37	别名	Nagilactone-C

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