CAS No.: 57149-07-2
Naftopidil/萘哌地尔 Catalog No. CSN11512
Synonyms: KT-611;BM-15275;Flivas
Naftopidil is a selective α1-adrenergic receptor antagonist or α blocker used for treatment for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01203371 Hyperplasia Phase 3 Unknown January 2012 Brazil ... more >> Hospital das Clínicas da Faculdade de Medicina da USP Not yet recruiting São Paulo, Brazil, 05403-010 Contact: Geraldo C Freire, PhD 55 11 3069-8082 Contact: Camila C Marin 55 11 3069-8082 camila.marin@ig.com.br Principal Investigator: Geraldo C Freire, PhD Collapse << NCT02034604 Neurogenic Lower Urinary Tract... more >> Dysfunction Collapse << Phase 4 Unknown April 2015 Korea, Republic of ... more >> Samsung Medical Center Recruiting Seoul, Korea, Republic of, 130-710 Contact: Kyu-Sung Lee, M.D., Ph.D. 82-2-3410-3554 ksleedr@skku.edu Contact: Hyun Wook You, M.D. 82-2-3410-1268 khdoct29@gmail.com Principal Investigator: Kyu-Sung Lee, Ph.D, M.D. Collapse << NCT01922375 Lower Urinary Tract Symptoms A... more >>ssociated With Benign Prostatic Hyperplasia Collapse << Phase 4 Completed - Korea, Republic of ... more >> Chonnam national university hospital Gwangju, Korea, Republic of Collapse << - 更多
- 参考文献
- [1] Kanda H, Ishii K, et al. Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. Int J Cancer. 2008 Jan 15;122(2):444-51.
- [2] Takei R, Ikegaki I, et al. Naftopidil, a novel alpha1-adrenoceptor antagonist, displays selective inhibition of canine prostatic pressure and high affinity binding to cloned human alpha1-adrenoceptors. Jpn J Pharmacol. 1999 Apr;79(4):447-54.
- [3] Takei R, Ikegaki I, Shibata K, Tsujimoto G, Asano T. Naftopidil, a novel alpha1-adrenoceptor antagonist, displays selective inhibition of canine prostatic pressure and high affinity binding to cloned human alpha1-adrenoceptors. Jpn J Pharmacol. 1999;79(4):447-454.
- [4] Kanda H, Ishii K, Ogura Y, et al. Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. Int J Cancer. 2008;122(2):444-451.
- [5] Masachika E, Kanno T, Nakano T, Gotoh A, Nishizaki T. Naftopidil induces apoptosis in malignant mesothelioma cell lines independently of α1-adrenoceptor blocking. Anticancer Res. 2013;33(3):887-894.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 57149-07-2 | 储存条件 |
|
|||||||||||||
| 分子式 | C24H28N2O3 | 运输 | 蓝冰 | |||||||||||||
| 分子量 | 392.49 | 别名 | KT-611;BM-15275;Flivas;萘哌地尔 | |||||||||||||
| 溶解度 |
|
动物实验配方 |
|
