CAS No.: 127-07-1
羟基脲 Catalog No. CSN16113
Synonyms: Hydroxycarbamide;NCI-C04831;NSC-32065
Hydroxyurea is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 作用机制
- 细胞研究
- Cell Data
动物研究 剂量 Mice: 25 mg/kg - 100 mg/kg[7] (i.p.)
给药途径 i.p.
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00002230 HIV Infections Phase 3 Completed - United States, Illinois ... more >> Northwestern Univ Med School Chicago, Illinois, United States, 60611 Collapse << NCT00000602 Anemia, Sickle Cell ... more >> Hematologic Diseases Hemoglobinopathies Collapse << Phase 2 Completed - - NCT01895361 Sickle Cell Disease Phase 2 Completed - - - 更多
- 参考文献
- [1] Elledge SJ, Zhou Z, et al. Ribonucleotide reductase: regulation, regulation, regulation. Trends Biochem Sci. 1992;17(3):119-23.
- [2] Tholander F, Sjöberg BM. Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format. Proc Natl Acad Sci U S A. 2012;109(25):9798-803.
- [3] Osterman Golkar S, Czene S, et al. Intracellular deoxyribonucleotide pool imbalance and DNA damage in cells treated with hydroxyurea, an inhibitor of ribonucleotide reductase. Mutagenesis. 2013;28(6):653-60.
- [4] Shi W, Feng Z, et al. The role of RPA2 phosphorylation in homologous recombination in response to replication arrest. Carcinogenesis. 2010;31(6):994-1002.
- [5] Guan Z, Wang X, et al. dNTP deficiency induced by HU via inhibiting ribonucleotide reductase affects neural tube development. Toxicology. 2015.
- [6] Iman M, Khansefid Z, et al. Modeling and Proposed Molecular Mechanism of Hydroxyurea Through Docking and Molecular Dynamic Simulation to Curtail the Action of Ribonucleotide Reductase. Recent Pat Anticancer Drug Discov. 2016;11(4):461-468.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 127-07-1 | 储存条件 |
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| 分子式 | CH4N2O2 | 运输 | 蓝冰 | |||||
| 分子量 | 76.05 | 别名 | Hydroxycarbamide;NCI-C04831;NSC-32065;Biosupressin;Carbamoyl oxime;Droxia;羟基脲 | |||||
| 溶解度 |
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动物实验配方 |
| Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
|---|
| L1210 Leukemia cells | - | Growth inhibition assay | - | Concentration required for 50% inhibition of cell growth (L1210 Leukemia), IC50=21.3796 μM | 2991520 |
| P388 leukemic cell | - | Proliferation assay | 24-48 h | Antiproliferative activity of compound expressed as concentration that inhibits 50% of growth of P388 leukemic cell suspension from 24 to 48 hr after compound addition, IC50=32 μM | 2709372 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT00002230 | HIV Infections | Phase 3 | Completed | - | United States, Illinois ... more >> Northwestern Univ Med School Chicago, Illinois, United States, 60611 Collapse << |
| NCT00000602 | Anemia, Sickle Cell ... more >> Hematologic Diseases Hemoglobinopathies Collapse << | Phase 2 | Completed | - | - |
| NCT01895361 | Sickle Cell Disease | Phase 2 | Completed | - | - |
| NCT02990598 | - | - | Active, not recruiting | November 2019 | United States, Ohio ... more >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229 Collapse << |
| NCT02769845 | Sickle Cell Anemia | Not Applicable | Recruiting | October 2020 | Dominican Republic ... more >> Encargada del Servicio de Hematología-Oncología Hospital Infantil Dr. Robert Reid Cabral Recruiting Santo Domingo, Dominican Republic Contact: Rosa Nieves, MD 809-533-1111 ext 2004 sacred.rr@gmail.com Collapse << |
| NCT00672789 | Sickle Cell Anemia | Not Applicable | Completed | - | United States, North Carolina ... more >> Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00008866 | HIV Infections | Phase 2 | Withdrawn | - | - |
| NCT03123588 | MPN (Myeloproliferative Neopla... more >>sms) Collapse << | Phase 2 | Recruiting | June 2020 | - |
| NCT02640573 | Hemoglobin SC Disease | Phase 2 | Terminated(Insufficient accrua... more >>l) Collapse << | - | United States, Texas ... more >> Baylor College of Medicine Houston, Texas, United States, 77030 University of Texas Houston Houston, Texas, United States, 77030 Collapse << |
| NCT03287245 | Polycythemia Vera | Phase 2 | Recruiting | March 30, 2021 | United States, Arizona ... more >> Mayo Clinic - Arizona Not yet recruiting Phoenix, Arizona, United States, 85054 United States, Kansas University of Kansas Cancer Center; Westwood Cancer Center/BMT Output Clinic Recruiting Kansas City, Kansas, United States, 66205 United States, New York Icahn School of Medicine at Mount Sinai Recruiting New York, New York, United States, 10029 Columbia Univ Med Ctr Recruiting New York, New York, United States, 10032 MSKCC Withdrawn New York, New York, United States, 10065 Weill Cornell Medical College Recruiting New York, New York, United States, 10065 United States, Ohio Cleveland Clinic Cancer Center Recruiting Independence, Ohio, United States, 44131 United States, Texas University of Texas Health Sciences Center in San Antonio Recruiting San Antonio, Texas, United States, 78229 Australia, Victoria Peter MacCallum Cancer Centre; Department of Haematology Active, not recruiting Melbourne, Victoria, Australia, 3002 Canada, Ontario Princess Margaret Hospital; Department of Med Oncology Recruiting Toronto, Ontario, Canada, M5G 2M9 Italy ASST PAPA GIOVANNI XXIII; Ematologia Recruiting Bergamo, Lombardia, Italy, 24127 Ospedale Di Circolo E Fondazione Macchi; Ematologia Recruiting Varese, Lombardia, Italy, 21100 Az. Ospedaliero-Universitaria Careggi; CRIMM Recruiting Firenze, Toscana, Italy, 50134 Collapse << |
| NCT00056433 | Sickle Cell Anemia | Phase 1 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT02197845 | Sickle Cell Disease | Not Applicable | Recruiting | December 2018 | United States, Virginia ... more >> Virginia Commonwealth University Recruiting Richmond, Virginia, United States, 23298 Principal Investigator: Wally R. Smith, MD Collapse << |
| NCT00023959 | Metastatic Squamous Neck Cance... more >>r With Occult Primary Squamous Cell Carcinoma Recurrent Adenoid Cystic Carcinoma of the Oral Cavity Recurrent Basal Cell Carcinoma of the Lip Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity Recurrent Lymphoepithelioma of the Nasopharynx Recurrent Lymphoepithelioma of the Oropharynx Recurrent Metastatic Squamous Neck Cancer With Occult Primary Recurrent Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity Recurrent Mucoepidermoid Carcinoma of the Oral Cavity Recurrent Salivary Gland Cancer Recurrent Squamous Cell Carcinoma of the Hypopharynx Recurrent Squamous Cell Carcinoma of the Larynx Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity Recurrent Squamous Cell Carcinoma of the Nasopharynx Recurrent Squamous Cell Carcinoma of the Oropharynx Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity Recurrent Verrucous Carcinoma of the Larynx Recurrent Verrucous Carcinoma of the Oral Cavity Stage III Adenoid Cystic Carcinoma of the Oral Cavity Stage III Basal Cell Carcinoma of the Lip Stage III Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity Stage III Inverted Papilloma of the Paranasal Sinus and Nasal Cavity Stage III Lymphoepithelioma of the Nasopharynx Stage III Lymphoepithelioma of the Oropharynx Stage III Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity Stage III Mucoepidermoid Carcinoma of the Oral Cavity Stage III Salivary Gland Cancer Stage III Squamous Cell Carcinoma of the Hypopharynx Stage III Squamous Cell Carcinoma of the Larynx Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity Stage III Squamous Cell Carcinoma of the Nasopharynx Stage III Squamous Cell Carcinoma of the Oropharynx Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity Stage III Verrucous Carcinoma of the Larynx Stage III Verrucous Carcinoma of the Oral Cavity Stage IV Adenoid Cystic Carcinoma of the Oral Cavity Stage IV Basal Cell Carcinoma of the Lip Stage IV Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity Stage IV Inverted Papilloma of the Paranasal Sinus and Nasal Cavity Stage IV Lymphoepithelioma of the Nasopharynx Stage IV Lymphoepithelioma of the Oropharynx Stage IV Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity Stage IV Mucoepidermoid Carcinoma of the Oral Cavity Stage IV Salivary Gland Cancer Stage IV Squamous Cell Carcinoma of the Hypopharynx Stage IV Squamous Cell Carcinoma of the Larynx Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity Stage IV Squamous Cell Carcinoma of the Nasopharynx Stage IV Squamous Cell Carcinoma of the Oropharynx Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity Stage IV Verrucous Carcinoma of the Larynx Stage IV Verrucous Carcinoma of the Oral Cavity Untreated Metastatic Squamous Neck Cancer With Occult Primary Collapse << | Phase 1 | Completed | - | United States, Illinois ... more >> University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637-1470 Collapse << |
| NCT00203905 | Head and Neck Cancer | Phase 2 | Completed | - | United States, Illinois ... more >> The University of Chicago Chicago, Illinois, United States, 60637 Collapse << |
| NCT00706810 | Cancer Brain ... more >>Cancer Meningioma Collapse << | Phase 2 | Completed | - | United States, Utah ... more >> Huntsman Cancer Institute Salt Lake City, Utah, United States, 84112 Collapse << |
| NCT01387763 | Polycythemia Vera ... more >> Essential Thrombocythemia Primary Myelofibrosis Collapse << | Phase 3 | Active, not recruiting | January 2020 | Denmark ... more >> Dept of Hematology, Aalborg hospital Aalborg, Denmark, 9000 Dept. of Hematology, Aarhus University Hospital Aarhus, Denmark, 8000 Dept of Hematology, Esbjerg Hospital Esbjerg, Denmark, 6700 Dept of Hematology, Herlev Hospital Herlev, Denmark, 2730 Dept of Hematology, Holstebro Hospital Holstebro, Denmark, 7500 Dept of Hematology, Rigshospitalet København, Denmark, 2100 Dept of hematology, Odense University Hospital Odense, Denmark, 5000 Dept. of Hematology, Roskilde Hospital Roskilde, Denmark, 4000 Collapse << |
| NCT00706810 | - | - | Completed | - | - |
| NCT01065038 | Essential Thrombocythaemia | Phase 3 | Completed | - | Austria ... more >> Center Innsbruck Innsbruck, Tirol, Austria, 6020 Center AKH Vienna, Austria, 1090 Center Hanusch Vienna, Austria, 1140 Czech Republic Center Brno Brno, Czech Republic, 62500 Center Olomouc Olomouc, Czech Republic, 77520 Center Praha Prague, Czech Republic, 12808 France Center Paris Paris, CLICHY Cedex, France, 92118 Germany Center Munich Munich, Bavaria, Germany, 80331 Center Berlin Berlin, Germany, 12200 Center Halle Halle, Germany, 06111 Center Saarbrücken Saarbrücken, Germany, 66113 Center Ulm Ulm, Germany, 89081 Hungary Center Budapest Budapest, Hungary, 1097 Italy Center Modena Modena, Italy, 41100 Center Pavia Pavia, Italy, 27100 Lithuania Center Vilnius Vilnius, Lithuania, 2600 Poland Center Gdansk Gdansk, Poland, 80-211 Center Katowice Katowice, Poland, 40-027 Center Krakow Krakow, Poland, 31-501 Center Lodz Lodz, Poland, 93-510 Center Lublin Lublin, Poland, 20-079 Center Warszawa Warszawa, Poland, 02-097 Singapore Center Singapore Singapore, Singapore, 169608 Slovenia Center Ljubljana Ljubljana, Slovenia Collapse << |
| NCT00890396 | - | - | Unknown | December 2011 | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 United States, District of Columbia Children's National Medical Center Washington, District of Columbia, United States, 20010 Howard University College of Medicine Washington, District of Columbia, United States, 20060 United States, Florida University of Miami School of Medicine Miami, Florida, United States, 33136 United States, Georgia Emory University School of Medicine Atlanta, Georgia, United States, 30342 United States, Maryland Johns Hopkins University School of Medicine Baltimore, Maryland, United States, 21205 United States, Michigan Children's Hospital of Michigan/Wayne State University Detroit, Michigan, United States, 48201 United States, Mississippi University of Mississippi Medical Center Jackson, Mississippi, United States, 39216 United States, New York Downstate Medical Center Brooklyn, New York, United States, 11203 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Pennsylvania Drexel University Philadelphia, Pennsylvania, United States, 19134 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 United States, Tennessee St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 United States, Texas University of Texas Southwestern Medical Center at Dallas Dallas, Texas, United States, 75390 Collapse << |
| NCT03715972 | - | - | Recruiting | March 2023 | United States, California ... more >> CHLA Recruiting Los Angeles, California, United States, 90027 Contact: Bertin B Valdez, BSc 323-361-1819 bvaldez@chla.usc.edu Contact: Natalie Ornelas 323.361.8827 nornelas@chla.usc.edu Principal Investigator: John C Wood, M.D, PhD Sub-Investigator: Thomas Coates, M.D Collapse << |
| NCT00532883 | Hemoglobin SC Disease | Phase 2 | Terminated(Enrollment has been... more >> terminated due to a slow rate of enrollment.) Collapse << | - | - |
| NCT00001074 | HIV Infections | Phase 1 | Completed | - | United States, California ... more >> Univ of California / San Diego Treatment Ctr San Diego, California, United States, 921036325 Stanford at Kaiser / Kaiser Permanente Med Ctr San Francisco, California, United States, 94115 Stanford Univ Med Ctr Stanford, California, United States, 943055107 Harbor UCLA Med Ctr Torrance, California, United States, 90502 United States, Colorado Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 United States, New York Beth Israel Med Ctr New York, New York, United States, 10003 Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 Mount Sinai Med Ctr New York, New York, United States, 10029 United States, North Carolina Univ of North Carolina Chapel Hill, North Carolina, United States, 275997215 Duke Univ Med Ctr Durham, North Carolina, United States, 27710 United States, Ohio Univ of Cincinnati Cincinnati, Ohio, United States, 452670405 Case Western Reserve Univ Cleveland, Ohio, United States, 44106 MetroHealth Med Ctr Cleveland, Ohio, United States, 441091998 United States, Pennsylvania Univ of Pennsylvania at Philadelphia Philadelphia, Pennsylvania, United States, 19104 Thomas Jefferson Univ Hosp Philadelphia, Pennsylvania, United States, 191075098 United States, South Carolina Julio Arroyo West Columbia, South Carolina, United States, 29169 United States, Washington Univ of Washington Seattle, Washington, United States, 981224304 Collapse << |
| NCT00202644 | Thrombocythemia, Hemorrhagic | Phase 4 | Completed | - | Bulgaria ... more >> University Multiprofile Hospital for Active Treatment ''Dr Georgi Stranski'' - Pleven Pleven, Bulgaria, 5800 University Multiprofile Hospital for active Treatment ''Alexandrovska'' Clinic of Haematology Sofia, Bulgaria, 1303 University Multiprofile Hospital for Active Treament ''Sv. Marina'' - Varna Haematology Clinic Varna, Bulgaria, 9010 France CHU Angers Services des Maladies du Sang Angers, Cedex 09, France, 49933 Hopital Saint Louis - Centre d'Investigation Clinique Paris, France Hungary University of Debrecen Medical and Health Science Centre Debrecen, Hungary, 4012 Petz Aladar County Teaching Hospital Gyor, Hungary, 9024 Pandy Kalman Hospital of Bekes County Gyula, Hungary, 5700 Kaposi Mor Teaching Hospital Kaposvar, Hungary, 7400 Poland Uniwersyteckie Centrum Kliniczne Katedra i Klinika Hematologii i Transplantologii Gdansk, Poland, 80-952 Samodzielny Publiczny Szpital Kliniczny Nr 1 Lublin, Poland, 21-081 Katedra i Klinika Onkologii i Chorob Wewnetrznych Akademii Medycznej Warsaw, Poland, 02-097 Klinika Hematologii Instytut Hematologii i Transfuzjologi Warsaw, Poland, 02-776 Portugal Hospitals da Universidade de Coimbra Coimbra, Portugal, 3000-076 Serbia Institute for Haematology of Clinical Centre of Serbia Belgrade, Serbia, 11000 Collapse << |
| NCT00000586 | Anemia, Sickle Cell ... more >> Hematologic Diseases Hemoglobinopathies Collapse << | Phase 3 | Completed | - | - |
| NCT00532883 | - | - | Terminated(Enrollment has been... more >> terminated due to a slow rate of enrollment.) Collapse << | - | - |
| NCT00180973 | LOCALLY ADVANCED UNDIFFERENTIA... more >>TED CARCINOMA NASOPHARYNGEAL TYPE UCNT Collapse << | Phase 3 | Unknown | - | France ... more >> Institut Gustave Roussy Villejuif, France, 94800 Collapse << |
| NCT00001958 | Beta Thalassemia ... more >> Hemoglobinopathy Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00480974 | - | - | Completed | - | Israel ... more >> Pediatric Hematology Unit - HaEmek Medical Center Afula, Israel, 18101 Collapse << |
| NCT00202644 | - | - | Completed | - | - |
| NCT00006119 | Brain and Central Nervous Syst... more >>em Tumors Collapse << | Phase 2 | Unknown | - | France ... more >> Hopital Saint Andre Bordeaux, France, 33075 Centre Leon Berard Lyon, France, 69373 Centre Regional de Lutte Contre le Cancer - Centre Val d'Aurelle Montpellier, France, 34298 Centre Eugene Marquis Rennes, France, 35042 Centre Hospitalier Universitaire Bretonneau de Tours Tours, France, 37044 Collapse << |
| NCT00122980 | Hemochromatosis ... more >> Cerebrovascular Accident Anemia, Sickle Cell Hematologic Diseases Collapse << | Phase 3 | Terminated(The study has been ... more >>stopped due to safety and futility concerns.) Collapse << | - | - |
| NCT00004933 | Leukemia | Phase 3 | Terminated(Poor accrual) | - | - |
| NCT00002940 | Lymphoma | Phase 2 | Completed | - | United States, Louisiana ... more >> Louisiana State University Health Sciences Center - Shreveport Shreveport, Louisiana, United States, 71130-3932 United States, Tennessee Saint Jude Children's Research Hospital Memphis, Tennessee, United States, 38105-2794 Collapse << |
| NCT00122980 | - | - | Terminated(The study has been ... more >>stopped due to safety and futility concerns.) Collapse << | - | - |
| NCT01632904 | Polycythemia Vera | Phase 3 | Completed | - | - |
| NCT00485511 | Spinal Muscular Atrophy | Phase 2 Phase 3 | Completed | - | Taiwan ... more >> Kaohsiung Medical University Hospital Kaohsiung, Taiwan, 807 Collapse << |
| NCT02556099 | Sickle Cell Anemia | Phase 2 | Recruiting | December 2024 | Jamaica ... more >> Sickle Cell Unit Recruiting Kingston, Jamaica Contact: Marvin Reid, MB BS PhD 876-927-1884 marvin.reid@uwimona.edu.jm Contact: Margaret Wisdom-Phipps, RN Margaret.wisdomphipps@uwimona.edu.jm Collapse << |
| NCT00568698 | Muscular Atrophy, Spinal | Phase 1 Phase 2 | Completed | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
| NCT00175838 | Thrombocythemia ... more >> Myeloproliferative Disorder Collapse << | Not Applicable | Completed | - | United Kingdom ... more >> Addenbrooke`s Hospital Cambridge, Cambs, United Kingdom, CB2 2QQ Collapse << |
| NCT01632904 | - | - | Completed | - | - |
| NCT00001197 | Sickle Cell Anemia | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00568802 | Muscular Atrophy, Spinal | Phase 1 Phase 2 | Unknown | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
| NCT01259856 | High Risk Polycythemia Vera ... more >> High Risk Essential Thrombocythemia Collapse << | Phase 3 | Completed | - | - |
| NCT01259856 | - | - | Completed | - | - |
| NCT00402480 | Stroke | Phase 2 | Completed | - | United States, North Carolina ... more >> Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00006400 | Hematologic Diseases ... more >> Anemia, Sickle Cell Collapse << | Phase 3 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 United States, District of Columbia Children's National Medical Center Washington, District of Columbia, United States, 20010 Howard University Washington, District of Columbia, United States, 20060 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, Georgia Emory University School of Medicine Atlanta, Georgia, United States, 30342 United States, Maryland Johns Hopkins University Baltimore, Maryland, United States, 21287 United States, Michigan Children's Hospital of Michigan/Wayne State Univ. Detroit, Michigan, United States, 48201 United States, Mississippi University of Mississippi Medical Center Jackson, Mississippi, United States, 39216 United States, New York SUNY Health Science Center, Brooklyn Brooklyn, New York, United States, 11203 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Pennsylvania Drexel University Philadelphia, Pennsylvania, United States, 19134 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 United States, Tennessee St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 United States, Texas University of Texas SW Medical Center Dallas, Texas, United States, 75390 Collapse << |
| NCT00143572 | Anemia, Sickle Cell | Phase 1 | Completed | - | United States, Tennessee ... more >> St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 Collapse << |
| NCT00904735 | Brain and Central Nervous Syst... more >>em Tumors Collapse << | Phase 2 | Unknown | - | Italy ... more >> Ospedale Civile Avellino Recruiting Avellino, Italy Contact: Contact Person 39-0825-203-232 Ospedale Bellaria Recruiting Bologna, Italy, I-40139 Contact: Alba A. Brandes, MD 39-51-622-5102 aa.brandes@yahoo.it Azienda Ospedaliero Careggi Recruiting Florence, Italy, 50139 Contact: Contact Person 39-055-427-7111 Istituto Nazionale Neurologico Carlo Besta Recruiting Milan, Italy, 20133 Contact: Contact Person 39-02-2394-2341 Ospedale Civile di Rovigo Recruiting Rovigo, Italy, 45100 Contact: Contact Person 39-0425-393-016 Collapse << |
| NCT00270478 | Sickle Cell Disease ... more >> Chronic Kidney Disease Pulmonary Hypertension Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT02522104 | Sickle Cell Disease ... more >> Renal Function Disorder Collapse << | Phase 4 | Completed | - | France ... more >> Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Henri-Mondor Creteil, France Collapse << |
| NCT03515018 | Leukemia, Chronic Myeloid | Phase 3 | Recruiting | May 1, 2020 | China, Heilongjiang ... more >> the First Affiliated Hospital of Harbin Medical University Recruiting Harbin, Heilongjiang, China, 150001 Contact: Jin Zhou, MD, PhD 008645185555951 zhoujin1111@126.com Collapse << |
| NCT00003590 | Adult Meningioma | Phase 2 | Completed | - | - |
| NCT00809042 | β-Thalassemia Intermedia | Phase 2 | Completed | - | Iran, Islamic Republic of ... more >> Hematology Research Center of Shiraz University of Medical Sciences Shiraz, Fars, Iran, Islamic Republic of Collapse << |
| NCT03344900 | - | - | Recruiting | December 2021 | United States, Tennessee ... more >> St. Jude Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Contact: Jane S. Hankins, MD, MS 866-278-5833 referralinfo@stjude.org Principal Investigator: Jane S. Hankins, MD, MS Collapse << |
| NCT01783990 | - | - | Unknown | December 2016 | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 United States, District of Columbia Children's National Medical Center Center for Cancer and Blood Disorders Washington, District of Columbia, United States, 20010 Howard University College of Medicine Washington, District of Columbia, United States, 20060 United States, Florida University of Miami School of Medicine Miami, Florida, United States, 33136 United States, Georgia Emory University School of Medicine Atlanta, Georgia, United States, 30342 United States, Maryland Johns Hopkins University School of Medicine Baltimore, Maryland, United States, 21205 Sinai Hospital of Baltimore Alfred I Coplan Pediatric Hematology Oncology Outpatient Center Baltimore, Maryland, United States, 21215 United States, Michigan Children's Hospital of Michigan/Wayne State University Detroit, Michigan, United States, 48201 United States, Mississippi University of Mississippi Medical Center Jackson, Mississippi, United States, 39216 United States, New York Downstate Medical Center Brooklyn, New York, United States, 11203 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 United States, Tennessee St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 United States, Texas University of Texas Southwestern Medical Center at Dallas Dallas, Texas, United States, 75390 Collapse << |
| NCT02336373 | Hemoglobin SC Disease | Phase 2 | Completed | - | United States, Texas ... more >> Texas Children's Hospital Houston, Texas, United States, 77030 Collapse << |
| NCT00003590 | - | - | Completed | - | - |
| NCT02480608 | Leukemia, Myelogenous, Chronic... more >>, BCR-ABL Positive Collapse << | Phase 1 Phase 2 | Completed | - | - |
| NCT01609192 | Drepanocytic Men Treated by Hy... more >>droxyurea for the First Time Collapse << | Phase 4 | Completed | - | France ... more >> Department of biology of reproduction (TENON Hospital- AP-HP) Paris, France, 75020 Collapse << |
| NCT00290771 | Recurrent Glioblastoma Multifo... more >>rme (GBM) Collapse << | Phase 2 | Terminated(Lack of efficacy) | - | United States, North Carolina ... more >> Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00290771 | - | - | Terminated(Lack of efficacy) | - | - |
| NCT01103583 | Multiple Sclerosis | Phase 2 Phase 3 | Terminated(No efficacy (interi... more >>m.analysis)) Collapse << | - | Italy ... more >> Centre for Experimental Neurological Therapies (CENTERS), Tor Vergata University Hospital Rome, Italy, 00133 Centre for Experimental Neurological Therapies (CENTERS), S.Andrea Hospital Rome, Italy, 00189 Collapse << |
| NCT02709681 | - | - | Completed | - | Italy ... more >> Ospedali Civili Riuniti di Sciacca Sciacca, Agrigento, Italy, 92019 Ospedale Vittorio Emanuele III Gela, Caltanisetta, Italy, 93012 Azienda Ospedaliero-Universitaria Bari, Italy U.O. Oncoematologia Pediatrica Ospedali Civili Brescia, Italy, 25100 Ospedale "A. Perrino" Brindisi, Italy, 72100 Azienda Ospedaliera Universitaria Di Cagliari Cagliari, Italy, 09121 Ospedale Vittorio Emanuele Catania, Italy, 95123 ARNAS "Garibaldi" Catania, Italy, 95124 University of Catania Catania, Italy, 95124 A.O. "Pugliese-Ciaccio" Catanzaro, Italy, 88100 Osp.San Giovanni Di Dio Crotone, Italy Azienda Ospedaliero Universitaria Meyer Firenze, Italy, 50139 E.O. Ospedali Galliera Genova, Italy, 16128 Università degli Studi di Milano Milano, Italy, 20122 Azienda Ospedaliero-Universitaria di Modena - Policlinico Modena, Italy, 41124 Clinica pediatrica Monza S. Gerardo Monza, Italy, 20052 Azienda Ospedaliera San Gerardo di Monza Monza, Italy, 20900 Aorn A. Cardarelli Napoli, Italy Clinica di Onco-Ematologia Pediatrica, Università di Padova Padova, Italy, 35128 A.R.N.A.S. "Civico" Palermo, Italy, 90100 Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello Palermo, Italy, 90146 Azienda Ospedaliero-Universitaria di Parma Parma, Italy, 43126 Policlinico San Matteo Pavia, Italy, 27100 Centro Emofilia e Medicina Trasfusionale - Pres. Ospedaliero Ravenna, Italy, 48121 A. O. Bianchi Melacrino Morelli Reggio Calabria, Italy, 89100 Ospedale S. Eugenio - FF UOSD DH Talassemici Roma, Italy, 00144 Università Cattolica del Sacro Cuore - Policlinico A.Gemelli Roma, Italy, 00168 U.O.S. Talassemia P.O. Umberto I° Siracusa, Italy, 96100 Università degli Suidi di Torino Torino, Italy, 90146 Policlinico G.B. Rossi Verona, Italy, 37122 Collapse << |
| NCT03462511 | Sickle Cell Disease | Not Applicable | Recruiting | June 2021 | United States, New York ... more >> Albert Einstein College of Medicine Recruiting Bronx, New York, United States, 10461 Contact: Karen Ireland 718-741-2402 kireland@montefiore.org Principal Investigator: Deepa Manwani, MD Feinstein Institute for Medical Research Not yet recruiting Manhasset, New York, United States, 11030 Contact: Antonella Farrell, BS, RN AFarrell@northwell.edu Principal Investigator: Banu Aygun, MD Columbia University Medical Center Recruiting New York, New York, United States, 10032 Contact: Dariana Pichardo, MSW 212-342-3943 dp2305@columbia.edu Principal Investigator: Nancy S Green, MD Principal Investigator: Arlene Smaldone, PhD, CPNP Sub-Investigator: Jean-Marie Bruzzese, PhD Sub-Investigator: Findley Sally, PhD Sub-Investigator: Stockwell Melissa, MD, MPH Sub-Investigator: Jia Haomiao, PhD United States, Pennsylvania The Children's Hospital of Philadelphia Not yet recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Courtney Babb, MS Principal Investigator: Kim Smith-Whitley, MD Collapse << |
| NCT00154375 | Glioblastoma Multiforme ... more >> Astrocytoma Collapse << | Phase 3 | Completed | - | Germany ... more >> Novartis Investigative Site Duelmen, Germany Collapse << |
| NCT00978146 | Desmoid Tumors ... more >> Fibromatosis Collapse << | Phase 2 | Withdrawn(Study was administra... more >>tively withdrawn by the IRB; no subjects were enrolled) Collapse << | January 2015 | - |
| NCT00336362 | Beta-Thalassemia | Not Applicable | Completed | - | Greece ... more >> George Papanicolaou Hospital Thessaloniki, Greece Collapse << |
| NCT02868138 | - | - | Completed | - | Turkey ... more >> Selma Unal Mersin, Turkey, 33169 Collapse << |
| NCT00154375 | - | - | Completed | - | - |
| NCT02225132 | Sickle Cell Disease | Early Phase 1 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT01949805 | Polycythemia Vera | Phase 3 | Completed | - | - |
| NCT00350844 | Sickle Cell Disease ... more >> Pulmonary Hypertension Collapse << | Phase 1 Phase 2 | Terminated(Low subject accrual... more >>) Collapse << | - | United States, Illinois ... more >> Children's Memorial Hospital Chicago, Illinois, United States, 60614-3394 Collapse << |
| NCT00305175 | - | - | Active, not recruiting | January 2026 | United States, Tennessee ... more >> St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 Collapse << |
| NCT03577691 | Sickle Cell Disease | Not Applicable | Recruiting | July 2021 | United States, Georgia ... more >> Grady Health System Recruiting Atlanta, Georgia, United States, 30303 Contact: Lakshmanan Krishnamurti, MD 404-727-9743 lakshmanan.krishnamurti@emory.edu Principal Investigator: Lakshmanan Krishnamurti, MD Hughes Spalding Children's Hospital Recruiting Atlanta, Georgia, United States, 30303 Contact: Lakshmanan Krishnamurthi, MD 404-727-9783 lakshmanan.krishnamurti@emory.edu Contact: Diana Ross 404-727-9783 diana.ross@emory.edu Principal Investigator: Lakshmanan Krishnamurthi, MD Children's Healthcare of Atlanta Recruiting Atlanta, Georgia, United States, 30322 Contact: Lakshmanan Krishnamurti, MD 404-727-9783 lakshmanan.krishnamurti@emory.edu Contact: Diana Ross, MSN, RN 404-727-9783 diana.ross@emory.edu Collapse << |
| NCT01531387 | Sickle Cell Anemia | Phase 3 | Terminated(inability to reach ... more >>a satisfactory endpoint with respect to adequate recruitment) Collapse << | - | United States, Tennessee ... more >> St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 Brazil Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti (HEMORIO) Centro, Rio de Janeiro, Brazil Jamaica Tropical Medicine Research Institute, University of the West Indies (UWI) Mona, Kingston, Jamaica Collapse << |
| NCT01531387 | - | - | Terminated(inability to reach ... more >>a satisfactory endpoint with respect to adequate recruitment) Collapse << | - | - |
| NCT00350844 | - | - | Terminated(Low subject accrual... more >>) Collapse << | - | - |
| NCT00387933 | Brain and Central Nervous Syst... more >>em Tumors Collapse << | Phase 1 | Completed | - | United States, North Carolina ... more >> Duke Comprehensive Cancer Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00519701 | Sickle Cell Anemia | Not Applicable | Completed | - | United States, North Carolina ... more >> Duke University Medican Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00354913 | Glioblastoma ... more >>Gliosarcoma Collapse << | Phase 2 | Completed | - | United States, North Carolina ... more >> Duke Cancer Institute Durham, North Carolina, United States, 27710 Collapse << |
| NCT00615927 | - | - | Completed | - | - |
| NCT02214407 | MDS | Phase 3 | Recruiting | December 2020 | France ... more >> CHU La Réunion - Site nord Not yet recruiting Saint-Denis, La Réunion, France, 97400 Contact: Tahar Touahri, MD tahar.touahri@chu-reunion.fr Principal Investigator: Tahar Touahri, MD CHU La Réunion-Site Sud Not yet recruiting Saint-Pierre, La Réunion, France, 97410 Contact: Patricia Zunic, MD patricia.zunic@chu-reunion.fr Principal Investigator: Patricia Zunic, MD Chu Amiens Recruiting Amiens, France, 80054 Contact: Lavinia Merlusca, MD 0322455915 merlusca.lavinia@chu-amiens.fr Principal Investigator: Lavinia Merlusca, MD CHU d'Angers Recruiting Angers, France, 49 000 Contact: Mathilde Hunault +33 2 41 35 44 75 MaHunault@chu-angers.fr Principal Investigator: Mathilde Hunault, Professor CH Victor Dupouy Not yet recruiting Argenteuil, France, 95107 Contact: Ahmad Al Jijakli, MD +33134232339 ahmad.aljijakli@ch-argenteuil.fr Principal Investigator: Ahmad Al Jijakli, MD Ch Avignon Recruiting Avignon, France, 84000 Contact: Bohrane Slama, MD 0432753132 bslama@ch-avignon.fr Principal Investigator: Bohrane Slama, MD Centre Hospitalier de La Cote Basque Not yet recruiting Bayonne, France, 64100 Contact: Anne Banos, MD 033559443832 abanos@ch-cotebasque.fr Principal Investigator: Anne Banos, MD Hôpital Nord Franche-Comté Not yet recruiting Belfort, France, 90015 Contact: Marius Moldovan, MD +33 3 84 98 23 17 marius.moldovan@hnfc.fr Principal Investigator: Marius Moldovan, MD Hôpital Avicenne Recruiting Bobigny, France, 93009 Contact: Thorsten Braun, MD (0) 33 1 48 95 70 51 thorsten.braun@avc.aphp.fr Principal Investigator: Thorsten Braun, MD CHU de Brest - Hôpital Morvan Not yet recruiting Brest, France, 29609 Contact: Jean-Richard Eveillard, MD 33 2 98 22 33 33 jean-richard.eveillard@chu-brest.fr Principal Investigator: Jean-Richard Eveillard, MD CHU Côte de Nacre Recruiting Caen, France, 14033 Contact: Stéphane CHEZE, MD 0033231272360 cheze-s@chu-caen.fr Principal Investigator: Stéphane CHEZE, MD Hôpital privé Sévigné Recruiting Cesson-Sévigné, France, 35510 Contact: Benoît Bareau, MD +33 2 23 21 05 50 benoit.bareau@gmail.com Principal Investigator: Benoît Bareau, MD CHU Estaing Recruiting Clermont-Ferrand, France, 63058 Contact: Benoit De RENZIS, MD 0334 73 75 00 65 bderenzis@chu-clermontferrand.fr Principal Investigator: Benoit De RENZIS, MD CH de Compiègne Not yet recruiting Compiègne, France, 60321 Contact: Sophie Dennetière, MD +33 3 44 23 63 47 s.dennetiere@ch-compiegnenoyon.fr Principal Investigator: Sophie Dennetière, MD Centre Hospitalier Sud-Francilien Not yet recruiting Corbeil-Essonnes, France, 91106 Contact: Célia Salanoubat, MD +33 1 60 90 31 78 celia.salanoubat@ch-sud-francilien.fr Principal Investigator: Célia Salanoubat, MD Centre Henri Mondor Recruiting Créteil, France, 94010 Contact: Andrea Toma, MD 0033149812057 andrea.toma@hmn.aphp.fr Principal Investigator: Andrea Toma, MD CHU Albert Michallon Recruiting Grenoble, France, 38043 Contact: Stéphane COURBY, MD 033 4 76 76 57 12 SCourby@chu-grenoble.fr Principal Investigator: Stéphane COURBY, MD Principal Investigator: Sophie Park, PHD CH Le Mans Recruiting Le Mans, France, 72000 Contact: Kamel Laribi, MD 0243434361 klaribi@ch-lemans.fr Principal Investigator: Kamel Laribi, MD Clinique Victor Hugo Not yet recruiting Le Mans, France, 72000 Contact: Anne Parcelier, MD +33 2 43 47 94 93 a.parcelier@i-l-c.fr Principal Investigator: Anne Parcelier, MD Hôpital Saint Vincent de Paul Not yet recruiting Lille, France, 59020 Contact: Laurent Pascal, MD, PHD +33320874532 pascal.laurent@ghicl.net Principal Investigator: Laurent Pascal, MD, PHD CHRU de Limoges Recruiting Limoges, France, 87046 Contact: Marie-Pierre Gourin, MD 0033555056651 marie-pierre.gourin@chu-limoges.fr Principal Investigator: Marie Pierre Gourin, MD Centre Hospitalier Lyon Sud Recruiting Lyon, France, 69495 Contact: Eric WATTEL, PHD,MD 033 4 72 11 74 01 eric.wattel@chu-lyon.fr Principal Investigator: Eric WATTEL, PHD,MD Institut Paoli-Calmette Recruiting Marseille, France, 13009 Contact: Norbert VEY, PHD,MD 033 4 91 22 37 54 veyn@marseille.fnclcc.fr Principal Investigator: Norbert VEY, PHD,MD Centre Hospitalier de Meaux Not yet recruiting Meaux, France, 77100 Contact: Loïc Fouillard, MD 033164653876 l-fouillard@ch-meaux.fr Principal Investigator: Loïc Fouillard, MD Clinique Beausoleil Not yet recruiting Montpellier, France, 34000 Contact: Sophie Auger-Quittet, MD +33467759999 s.auger-quittet@languedoc-mutualite.fr Principal Investigator: Sophie Auger-Quittet, MD Hôpital Saint Eloi Recruiting Montpellier, France, 34295 Contact: Robert Navarro, MD +33467338362 r-navarro@chu-montpellier.fr Principal Investigator: Robert Navarro, MD Hopital de l'Hotel Dieu Recruiting Nantes, France, 44093 Contact: Pierre Peterlin, MD +33 2 40 08 32 71 pierre.peterlin@chu-nantes.fr Principal Investigator: Pierre Peterlin, MD Hopital Archet I Not yet recruiting Nice, France, 06202 Contact: Laurence LEGROS, MD 00 33 4 92 03 58 44 legros.l@chu-nice.fr Principal Investigator: Laurence LEGROS, MD CHU de Nîmes Recruiting Nîmes, France, 30029 Contact: Stefan Wickenhauser, MD +33 4 66 68 40 33 stefan.wickenhauser@chu-nimes.fr Principal Investigator: Stefan Wickenhauser, MD CHR d'Orléans Recruiting Orléans, France, 45067 Contact: Ali Arar, MD +33238229546 ali.arar@chr-orleans.fr Principal Investigator: Ali Arar, MD Hopital St Louis T4 Recruiting Paris, France, 75475 Contact: Pierre Fenaux, PHD 0171207022 pierre.fenaux@sls.aphp.fr Principal Investigator: Pierre Fenaux, PHD Principal Investigator: ITZYKSON Raphael, MD Centre Hospitalier Joffre Recruiting Perpignan, France, 66046 Contact: Laurence Sanhes, MD 00 33 468616448 laurence.sanhes@ch-perpignan.fr Principal Investigator: Laurence Sanhes, MD CHU de Haut-Lévèque Not yet recruiting Pessac, France, 33604 Contact: Sophie Dimicoli-Salazar, MD 033557656511 sophie.dimicoli-salazar@chu-bordeaux.fr Principal Investigator: Sophie Dimicoli-Salazar, MD CHU Poitiers Recruiting Poitiers, France, 86021 Contact: Jose Miguel Torregrosa Diaz, MD +33548444444 jose-miguel.torregrosa-diaz@chu-poitiers.fr Principal Investigator: Jose Miguel Torregrosa Diaz, MD CH René Dubos Not yet recruiting Pontoise, France, 95000 Contact: Riad Benramdane, MD +33156831442 benramdaner@yahoo.fr Principal Investigator: Riad Benramdane, MD CH Annecy Genevois Not yet recruiting Pringy, France, 74374 Contact: Pascale Cony-Makhoul, MD +33 4 50 63 64 31 pconymakhoul@ch-annecygenevois.fr Principal Investigator: Pascale Cony-Makhoul, MD CHU de Reims Not yet recruiting Reims, France, 51092 Contact: Chantal HIMBERLIN, MD 003326783644 chimberlin@chu-reims.fr Principal Investigator: Chantal HIMBERLIN, MD CHU Pontchaillou Recruiting Rennes, France, 35033 Contact: Stanislas Nimubona, MD 33299289521 stanislas.nimubona@chu-rennes.fr Principal Investigator: Stanislas Nimubona, MD Centre Henri Bequerel Recruiting Rouen, France, 76038 Contact: Aspasia STAMATOULLAS, MD 00 33 2 32 08 22 88 aspasia.stamatoullas@chb.unicancer.fr Principal Investigator: Aspasia STAMATOULLAS, MD Hôpital Hautepierre Not yet recruiting Strasbourg, France, 67098 Contact: Shanti Natarajan-Ame, MD +33388121670 shanti.ame@chru-strasbourg.fr Principal Investigator: Shanti Natarajan-Ame, MD IUCT Oncopole - Département d'hématologie Not yet recruiting Toulouse, France, 31059 Contact: Christian RECHER, MD, PHD 05 61 77 20 78 recher.christian@iuct-oncopole.fr Principal Investigator: Christian RECHER, MD Iuct Oncopole Recruiting Toulouse, France, 31059 Contact: Odile BEYNE-RAUZY, MD, PHD +33(0)5 31 15 62 64 beynerauzy.odile@iuct-oncopole.fr Principal Investigator: Odile Beyne-Rauzy, PHD CH Valence Not yet recruiting Valence, France, 26953 Contact: Jixing Liu, MD +33475757566 jliu@ch-valence.fr Principal Investigator: Jixing Liu, MD CHU Brabois Not yet recruiting Vandœuvre-lès-Nancy, France, 54511 Contact: Agnès GUERCI-BRESLER, MD 0033383153281 a.guerci@chu-nancy.fr Principal Investigator: Agnès GUERCI-BRESLER, MD Institut gustave Roussy Not yet recruiting Villejuif, France, 94805 Contact: Eric Solary, MD +33142114507 eric.solary@igr.fr Principal Investigator: ERIC SOLARY, MD Collapse << |
| NCT02844673 | Sickle Cell Anaemia | Phase 4 | Unknown | August 2017 | - |
| NCT00354913 | - | - | Completed | - | - |
| NCT02029742 | Sickle Cell Disease | Not Applicable | Completed | - | United States, New York ... more >> Montefiore Medical Center - Albert Einstein College of Medicine Bronx, New York, United States, 10461 Columbia University Medical Center New York, New York, United States, 10032 Collapse << |
| NCT01425307 | Sickle Cell Anemia | Phase 3 | Terminated(The study was stopp... more >>ed early due to successfully meeting the primary endpoint) Collapse << | - | - |
| NCT00784082 | - | - | Completed | - | France ... more >> Hopital Louis Mourier Colombes, France, 92701 Collapse << |
| NCT00928707 | Polycythemia Vera | Phase 2 | Completed | - | Italy ... more >> Azienda Ospedaliero-Universitaria Policlinico Consorziale di Bari Bari, BA, Italy, 70124 Azienda Ospedaliera Santa Croce e Carle di Cuneo Cuneo, CN, Italy, 12100 Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione Garibaldi di Catania Catania, CT, Italy, 95126 Fondazione I. R. C. C. S. - Casa sollievo della sofferenza di San Giovanni Rotondo San Giovanni Rotondo, FG, Italy, 71013 Azienda Ospedaliero-Universitaria Careggi di Firenze Florence, FI, Italy, 50134 Azienda Ospedaliera San Gerardo di Monza Monza, MB, Italy, 20052 Azienda Ospedaliera Universitaria Policlinico "Gaetano Martino" di Messina Messina, ME, Italy, 98125 Azienda Ospedaliera Ospedali Riuniti "Villa Sofia - Cervello" di Palermo Palermo, PA, Italy, 90146 Azienda Unità Sanitaria Locale di Pescara, Presidio Ospedaliero "Spirito Santo" Pescara, PE, Italy, 65124 Azienda Ospedaliera Santa Maria della Misericordia di Perugia Perugia, PG, Italy, 06156 Azienda Ospedaliera Universitaria Pisana Pisa, PI, Italy, 56126 Azienda Ospedaliera Ospedale San Carlo di Potenza Potenza, PT, Italy, 85100 Fondazione I.R.C.C.S.-Policlinico San Matteo, Pavia Pavia, PV, Italy, 27100 Azienda Ospedaliera "Bianchi-Melacrino-Morelli" Reggio di Calabria, RC, Italy, 891225 Azienda Ospedaliera Universitaria S. Luigi Gonzaga di Orbassano Orbassano, TO, Italy, 10043 Azienda Ospedaliero-Universitaria San Giovanni Battista("Le Molinette") di Torino Torino, TO, Italy, 10126 Ospedale Mauriziano Umberto I Torino, TO, Italy, 10128 Ospedale San Bortolo di Vicenza Vicenza, VI, Italy, 36100 Azienda Ospedaliera Ospedali Riuniti di Bergamo Bergamo, Italy, 24100 Azienda Ospedaliera Universitaria Università degli Studi di Napoli Federico II Napoli, Italy, 80131 Università "Campus Bio-Medico", Rome Rome, Italy, 00128 Policlinico Universitario Agostino Gemelli di Roma Rome, Italy, 00168 Collapse << |
| NCT00613132 | Glioblastoma ... more >>Gliosarcoma Collapse << | Phase 1 | Completed | - | United States, North Carolina ... more >> Duke University Health System Durham, North Carolina, United States, 27710 Collapse << |
| NCT02149537 | Sickle Cell Disease ... more >> Sickle Cell Anemia Collapse << | Phase 4 | Active, not recruiting | September 2019 | Nigeria ... more >> University of Ibadan College of Medicine Ibadan, Oyo State, Nigeria Collapse << |
| NCT00615927 | Glioblastoma ... more >>Gliosarcoma Collapse << | Phase 2 | Completed | - | United States, North Carolina ... more >> Duke University Health System Durham, North Carolina, United States, 27710 Collapse << |
| NCT02042222 | Sickle Cell Disease | Early Phase 1 | Recruiting | October 2019 | United States, Texas ... more >> Texas Children's Hospital Recruiting Houston, Texas, United States, 77030 Contact: Alex George, MD, PhD 832-822-4583 axgeorge@txch.org Collapse << |
| NCT01976416 | Sickle Cell Anemia ... more >> Sickle Cell Disease Malaria Collapse << | Phase 3 | Completed | - | Uganda ... more >> Mulago Hospital Sickle Cell Clinic Kampala, Uganda Collapse << |
| NCT01950585 | Pulmonary Hypertension | Early Phase 1 | Withdrawn | - | - |
| NCT02560935 | Sickle Cell Disease ... more >> Stroke Collapse << | Phase 3 | Active, not recruiting | December 2021 | Nigeria ... more >> Barau Dikko Teaching Hospital/Kaduna State University Kaduna, Nigeria Aminu Kano Teaching Hospital Kano, Nigeria Murtala Muhammad Specialist Hospital Kano, Nigeria Collapse << |
| NCT01425307 | - | - | Terminated(The study was stopp... more >>ed early due to successfully meeting the primary endpoint) Collapse << | - | - |
| NCT01976416 | - | - | Completed | - | - |
| NCT02286154 | Anemia, Sickle Cell | Not Applicable | Recruiting | October 2024 | United States, Ohio ... more >> Cincinnati Children's Hospital Medical Center Recruiting Cincinnati, Ohio, United States, 45229 Contact: Patrick McGann, MD, MS 513-803-4991 patrick.mcgann@cchmc.org Contact: Amanda Pfeiffer, LPC, CCRP (513)803-4977 amanda.pfeiffer@cchmc.org Collapse << |
| NCT01624038 | Thalassemia Intermedia | Phase 2 Phase 3 | Unknown | December 2012 | Egypt ... more >> hematology clinic ,pediatrics hospital, Ain Shams University hospital Not yet recruiting Cairo, Egypt Principal Investigator: Mohsen Saleh El-Alfy, professor of pediatrics Collapse << |
| NCT01521299 | Advanced Solid Tumors | Phase 1 | Withdrawn(Insufficient populat... more >>ion of eligible patients.) Collapse << | December 2013 | - |
| NCT03062501 | Anemia, Sickle Cell ... more >> Anemia; Sickle-Cell, With Crisis Collapse << | Phase 2 | Recruiting | July 2017 | Brazil ... more >> Hemorio Recruiting Rio de Janeiro, Brazil Contact: Thais Oliveira, B.Sc. +55 (21) 2505-0750 ext 2212 cdi@hemorio.rj.gov.br Collapse << |
| NCT03763656 | Anemia, Sickle Cell | Phase 2 | Recruiting | January 2020 | Jamaica ... more >> Dr Angela E Rankine- Mullings Recruiting Kingston, Jamaica Contact: Angela E Rankine- Mullings, MD 1 (876)927-2471 ext 249 angela.rankinemullings@uwimona.edu.jm Collapse << |
| NCT03020615 | Sickle Cell Anemia | Phase 2 | Recruiting | September 30, 2020 | United States, Georgia ... more >> Emory University/Children's Health Care of Atlanta Recruiting Atlanta, Georgia, United States, 30322 Contact: Robert C. Brown, MD 404-785-3641 clark.brown@choa.org Principal Investigator: Robert C. Brown, MD United States, Mississippi University of Mississippi Medical Center Recruiting Jackson, Mississippi, United States, 39216 Contact: Melissa McNaull, MD 601-984-5220 mrhodes@umc.edu Principal Investigator: Melissa McNaull, MD United States, Tennessee St. Jude Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Contact: Jeremie Estepp, MD 866-278-5833 referralinfo@stjude.org Principal Investigator: Jeremie Estepp, MD United States, Texas University of Texas Southwestern Medical Center at Dallas Recruiting Dallas, Texas, United States, 75390-9063 Contact: Zora Rogers, MD 214-648-4374 zora.rogers@UTSouthwestern.edu Principal Investigator: Zora Rogers, MD Collapse << |
| NCT01389024 | Sickle Cell Disease ... more >> Stroke Collapse << | Phase 2 | Recruiting | August 2019 | United States, Alabama ... more >> University of Alabama Recruiting Birmingham, Alabama, United States, 35233 Contact: Jeanie Dumas 205-939-9285 Jeanine.Dumas@childrensal.org Contact: Jeffrey Lebensberger, MD 410-639-6662 jlebensburger@peds.uab.edu Principal Investigator: Jeffrey Lebensburger, MD United States, Maryland Sinai Hospital Recruiting Baltimore, Maryland, United States, 21215 Contact: Jason Fixler, MD 410-601-6175 Jfixler@lifebridgehealth.org Principal Investigator: Jason Fixler, MD Johns Hopkins Hospital Recruiting Baltimore, Maryland, United States, 21287 Contact: Diane Weiss, BA 410-955-6132 dweiss14@jhmi.edu Contact: Lydia Pecker, MD 410-955-6732 lpecker1@jhmi.edu Sub-Investigator: Lydia Pecker, MD United States, Missouri Mercy Children's Hospital Recruiting Kansas City, Missouri, United States, 64108 Contact: Erin Bilynsky 816-234-3265 erbilynsky@cmh.edu Contact: Ram Kalpatthi, MD 8162343265 rvkalpatthi@cmh.edu] Principal Investigator: Ram Kalpatthi, MD St. Louis Children's Hospital Recruiting Saint Louis, Missouri, United States, 63110 Contact: Alison King, MD, MPH 314-286-1601 king_a@wustl.edu Principal Investigator: Alison King, MD, MPH United States, New York Columbia University Recruiting New York, New York, United States, 10032 Contact: Elena Gallagher, RN 212-305-0625 emg2178@cumc.columbia.edu Contact: Nancy Green, MD 212-305-0494 nsg11@cumc.columbia.edu Principal Investigator: Nancy Green, MD United States, Pennsylvania Children's Hospital of Philadelphia Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Helen Stanley 267-426-5602 stanleyh1@email.chop.edu Contact: Janet Kwiatkowski, MD, MHS 215-590-5286 Kwiatkowski@email.chop.edu Principal Investigator: Janet Kwiatkowski, MD, MHS Collapse << |
| NCT01848925 | Sickle Cell Disease | Phase 1 | Completed | - | Colombia ... more >> Fundacion BIOS Barranquilla, Colombia Fundacion Reina Isabel Cali, Colombia Hospital Pablo TobinUribe Medellin, Colombia Panama PAMRI Panama City, Panama Collapse << |
| NCT03128515 | Sickle Cell Anemia ... more >> Sickle Cell Disease Malaria Collapse << | Phase 3 | Recruiting | December 2020 | Uganda ... more >> Mulago Hospital Sickle Cell Clinic Recruiting Kampala, Uganda Contact: Robert O. Opoka, MBChB, MMED +256 772996164 opokabob@yahoo.com Principal Investigator: Christopher Ndugwa, MBChB, MMED Sub-Investigator: Robert O. Opoka, MBChB, MMED Sub-Investigator: Phillip Kasirye, MBChB, MMED Sub-Investigator: Heather Hume, M.D. Sub-Investigator: Russell E. Ware, M.D., Ph.D. Collapse << |
| NCT03442114 | Sickle Cell Anemia ... more >> Children, Only Collapse << | Not Applicable | Recruiting | November 30, 2020 | United States, California ... more >> Children's Hospital and Research Center at Oakland Not yet recruiting Oakland, California, United States, 94609 Contact: Lynne Neumayr, MD United States, District of Columbia Howard University Recruiting Washington, District of Columbia, United States, 20060 Contact: Sohail Rana, MD Principal Investigator: Sohail Rana, MD United States, Illinois Ann & Robert H Lurie Children's Hospital of Chicago Not yet recruiting Chicago, Illinois, United States, 60611 Contact: Sherif Badawy, MD Sub-Investigator: Alexis Thompson, MD United States, Missouri The Washington University Not yet recruiting Saint Louis, Missouri, United States, 63110 Contact: Allison King, MD Sub-Investigator: Cecelia Calhoun, MD United States, Ohio Nationwide Children's Hospital Recruiting Columbus, Ohio, United States, 43205 Contact: Susan Creary, MD Principal Investigator: Susan Creary, MD United States, Pennsylvania Children's Hospital of Philadelphia Not yet recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Kimberly Smith-Whitley, MD Principal Investigator: Kimberly Smith-Whitley, MD United States, Tennessee Vanderbilt University Medical Center Not yet recruiting Nashville, Tennessee, United States, 37232 Contact: Emmanuel Volanakis, MD United States, Texas Baylor College of Medicine Not yet recruiting Houston, Texas, United States, 77030 Contact: Jean Raphael, MD Sub-Investigator: Amber Yates, MD Collapse << |
| NCT01506544 | Sickle Cell Anemia | Phase 1 | Completed | - | United States, Alabama ... more >> Children's Hospital of Alabama Birmingham, Alabama, United States, 35233 United States, Illinois Children's Memorial Hospital (Northwestern University) Chicago, Illinois, United States, 60614-3363 United States, New York Columbia University Medical Center New York, New York, United States, 10032 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Texas UT Southwestern University Hospital Dallas, Texas, United States, 75390-9063 United States, Wisconsin Children's Hospital of Wisconsin Wauwatosa, Wisconsin, United States, 53226 Collapse << |
| NCT01801423 | Sickle Cell Anemia ... more >> Sickle Cell Disease Stroke Collapse << | Not Applicable | Active, not recruiting | September 2021 | Nigeria ... more >> Aminu Kano Teaching Hospital Kano, Nigeria, P.MB. 3452 Collapse << |
| NCT03183375 | Thalassemia, Beta | Phase 2 | Recruiting | June 30, 2018 | Pakistan ... more >> Omair Sana Foundation Recruiting Karachi, Sindh, Pakistan, 75300 Contact: Saqib H Ansari, MBBS, DCH, DPGN, Mphil, PhD 03002118018 muddasirsaqib@yahoo.com Contact: Salima M Ali, BScN, MS 03322696554 sohanisalima@gmail.com Collapse << |
| NCT03463733 | Glioma Gliobl... more >>astoma Collapse << | Phase 1 | Recruiting | June 2020 | Netherlands ... more >> VU University Medical Center Recruiting Amsterdam, Noord-Holland, Netherlands, 1081 HV Contact: H.M.W Verheul, MD, PhD +31 (0)20 4444321 h.verheul@vumc.nl Collapse << |
| NCT00613054 | Glioblastoma ... more >>Gliosarcoma Collapse << | Phase 1 | Completed | - | United States, North Carolina ... more >> Duke University Health System Durham, North Carolina, United States, 27710 Collapse << |
| NCT02675790 | Sickle Cell Disease ... more >> Sickle Cell Anemia Stroke Collapse << | Phase 3 | Recruiting | December 2020 | Nigeria ... more >> Aminu Kano Teaching Hospital Recruiting Kano, Nigeria Contact: Shehu Abdullahi, MD, FWACPaed 234-802-326-8363 dr_suak@yahoo.com Contact: Bilya Musa 234-803-600-5052 bilyasani@yahoo.com Murtala Muhammad Specialist Hospital Recruiting Kano, Nigeria Contact: Binta Jibir, MBBS, MTroped, FWACP 234-803-700-2249 hajiyakarama@yahoo.co.uk Collapse << |
| NCT01966731 | Sickle Cell Disease | Phase 1 Phase 2 | Active, not recruiting | August 2033 | Angola ... more >> Hospital Pediátrico David Bernardino Luanda, Angola Congo, The Democratic Republic of the Centre Hospitalier Monkole Kinshasa, Congo, The Democratic Republic of the Kenya KEMRI/Wellcome Trust Research Kilifi, Kenya Uganda Ministry of Health Mbale Regional Hospital Mbale, Uganda Collapse << |
| NCT03644953 | Sickle Cell Disease | Phase 2 | Recruiting | August 2020 | United States, District of Col... more >>umbia Children's National Health System Recruiting Washington, District of Columbia, United States, 20010 Contact: Robert S Nickel, MD, MSc Collapse << |
| NCT00632255 | - | - | Completed | - | United Kingdom ... more >> Haematology Department. Catherine Lewis Centre. Hammersmith Hospital. Du Cane Road. London, United Kingdom, W12 0HS Collapse << |
| NCT01174056 | Lung Inflammation | Early Phase 1 | Completed | - | United States, Missouri ... more >> Washington University / Barnes Jewish Hospital St. Louis, Missouri, United States, 63110 Collapse << |
| NCT03013998 | Previously Untreated Acute Mye... more >>loid Leukemia Collapse << | Phase 1 Phase 2 | Recruiting | December 2021 | United States, Arizona ... more >> Mayo Clinic Arizona Recruiting Phoenix, Arizona, United States, 85054 Principal Investigator: Lisa Sproat, MD United States, California UCLA Ronald Reagan Medical Center Recruiting Los Angeles, California, United States, 90095 Principal Investigator: Gary Schiller, MD University of California, San Francisco Recruiting San Francisco, California, United States, 94143 Principal Investigator: Gabriel Mannis, MD United States, Colorado University of Colorado Recruiting Denver, Colorado, United States, 80203 Principal Investigator: Dan Pollyea, MD United States, Florida Mayo Clinic Florida Recruiting Jacksonville, Florida, United States, 32224 Principal Investigator: James Foran, MD United States, Georgia Emory University Recruiting Atlanta, Georgia, United States, 30308 Principal Investigator: William Blum, MD United States, Illinois University of Chicago Recruiting Chicago, Illinois, United States, 60637 Principal Investigator: Wendy Stock, MD United States, Maryland University of Maryland Medical Center Recruiting Baltimore, Maryland, United States, 21201 Principal Investigator: Maria Baer, MD United States, New York Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Principal Investigator: Eytan M Stein, MD United States, Ohio Ohio State University Recruiting Columbus, Ohio, United States, 43210 Principal Investigator: John C Byrd, MD Principal Investigator: Alice Mims, MD Principal Investigator: Alison R Walker, MD, MPH United States, Oregon Oregon Health & Science University Recruiting Portland, Oregon, United States, 97239 Principal Investigator: Uma Borate, MD United States, Texas University of Texas Southwestern Recruiting Dallas, Texas, United States, 75390 Principal Investigator: Prapti Patel, MD United States, Utah Huntsman Cancer Institute, University of Utah Recruiting Salt Lake City, Utah, United States, 84112 Principal Investigator: Michael Deininger, MD, PhD Collapse << |
| NCT03716726 | Sickle Cell Disease | Not Applicable | Not yet recruiting | December 2022 | - |
| NCT00306202 | Leukemia | Phase 1 | Active, not recruiting | October 4, 2022 | Austria ... more >> Local Institution Vienna, Austria, 1090 France Local Institution Nantes, France, 44093 Local Institution Paris Cedex 10, France, 75475 Local Institution Paris Cedex 12, France, 75571 Germany Local Institution Berlin, Germany, 13353 Local Institution Frankfurt, Germany, 60590 Local Institution Hannover, Germany, 30625 Italy Local Institution Monza (mi), Italy, 20052 Netherlands Local Institution Rotterdam, Netherlands, 3015 GJ United Kingdom Local Institution Manchester, Greater Manchester, United Kingdom, M27 4HA Local Institution Bristol, Somerset, United Kingdom, BS2 8BJ Local Institution Sutton, Surrey, United Kingdom, SM2 5PT Local Institution Birmingham, West Midlands, United Kingdom, B4 6NH Collapse << |
| NCT00017771 | - | - | Completed | - | United States, Alabama ... more >> Univ of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, California UCLA CARE Ctr Los Angeles, California, United States, 90095 United States, Colorado Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Hawaii Univ of Hawaii Honolulu, Hawaii, United States, 96816 United States, Illinois The CORE Ctr Chicago, Illinois, United States, 60612 United States, Indiana Indiana Univ Hosp Indianapolis, Indiana, United States, 462025250 Methodist Hosp of Indiana / Life Care Clinic Indianapolis, Indiana, United States, 46202 Wishard Hosp Indianapolis, Indiana, United States, 46202 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 United States, Missouri Washington Univ / St Louis Connect Care Saint Louis, Missouri, United States, 63108 Washington Univ School of Medicine St Louis, Missouri, United States, 63108 United States, New York Beth Israel Med Ctr New York, New York, United States, 10003 Cornell Univ Med Ctr New York, New York, United States, 10021 Univ of Rochester Medical Center Rochester, New York, United States, 14642 United States, Pennsylvania Univ of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Mount Sinai Med Ctr Pittsburgh, Pennsylvania, United States, 15213 United States, Texas Univ of Texas, Southwestern Med Ctr of Dallas Dallas, Texas, United States, 75390 United States, Washington Univ of Washington Seattle, Washington, United States, 98104 Collapse << |
| NCT01566890 | Sickle Cell Disease ... more >> Sickle Cell Anemia Collapse << | Not Applicable | Active, not recruiting | December 31, 2019 | United States, Illinois ... more >> The University of Illinois Chicago, Illinois, United States, 60607 United States, Wisconsin Medical College of Wisconsin Milwaukee, Wisconsin, United States, 53226 Collapse << |
| NCT02551718 | Acute Leukemia of Ambiguous Li... more >>neage Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Myeloid Leukemia Recurrent Childhood Acute Lymphoblastic Leukemia Recurrent Childhood Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia Refractory Adult Acute Lymphoblastic Leukemia Refractory Childhood Acute Lymphoblastic Leukemia Collapse << | Not Applicable | Recruiting | - | United States, Washington ... more >> Fred Hutch/University of Washington Cancer Consortium Recruiting Seattle, Washington, United States, 98109 Contact: Pamela S. Becker 206-616-1589 pbecker@u.washington.edu Principal Investigator: Pamela S. Becker Collapse << |
| NCT00262405 | Idiopathic Pulmonary Fibrosis | Phase 2 | Completed | - | United States, Michigan ... more >> University of Michigan Ann Arbor, Michigan, United States, 48109 Collapse << |
| NCT00449319 | Leukemia, Myelocytic, Acute | Not Applicable | Recruiting | July 2018 | Italy ... more >> Prof. Mozzana Recruiting Gallarate, Italy Dr. De Blasio Recruiting Latina, Italy Prof. Nalli Recruiting Lodi, Italy Prof. Bordigon Recruiting Milano, Italy Dr Miraglia Recruiting Napoli, Italy Dr. Mettivier Recruiting Napoli, Italy Dr.ssa Mastrullo Recruiting Napoli, Italy Prof. Pane Recruiting Napoli, Italy Prof. D'Arco Recruiting Nocera Inferiore, Italy Dr Avanzi Recruiting Novara, Italy Dr. Gabbas Recruiting Nuoro, Italy Prof. Saglio Recruiting Orbassano, Italy Dr Mirto Recruiting Palermo, Italy Prof. Citarrella Recruiting Palermo, Italy Prof. Mariani Recruiting Palermo, Italy Prof. Rizzoli Recruiting Parma, Italy Pr. Mecucci Recruiting Perugia, Italy Prof. Falini Recruiting Perugia, Italy Prof. Martelli Recruiting Perugia, Italy Dr. Fioritoni Recruiting Pescara, Italy Pr. Petrini Recruiting Pisa, Italy Dr. Ricciuti Recruiting Potenza, Italy Dr. Nobile Recruiting Reggio Calabria, Italy Dr. Andriani Recruiting Roma, Italy Dr. Majolino Recruiting Roma, Italy Pr. Amadori Recruiting Roma, Italy Pr. Annino Recruiting Roma, Italy Pr. Leone Recruiting Roma, Italy Pr. Lo Coco Recruiting Roma, Italy Dr. Santoro Recruiting Rozzano, Italy Pr. Carella Recruiting San Giovanni Rotondo, Italy Pr. Longinotti Recruiting Sassari, Italy Dr Epis Recruiting Sondalo, Italy Dr. Russo Recruiting Taormina, Italy Dr Mazza Recruiting Taranto, Italy Pr. Boccadoro Recruiting Torino, Italy Collapse << |
| NCT02410811 | - | - | Recruiting | January 2022 | United States, Ohio ... more >> Cincinnati Children's Hospital Medical Center Recruiting Cincinnati, Ohio, United States, 45229 Contact: Courtney Little, RN, M.S. 513-636-6770 Sicklecell@cchmc.org Collapse << |
| NCT02577406 | Leukemia, Myeloid ... more >> Isocitrate Dehydrogenase Collapse << | Phase 3 | Recruiting | July 28, 2022 | - |
| NCT00009581 | Sickle Cell Anemia | Phase 2 | Completed | - | United States, Maryland ... more >> Warren G. Magnuson Clinical Center (CC) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00552188 | Acute Coronary Syndrome | Phase 2 | Completed | - | United States, California ... more >> VIA Pharmaceuticals San Francisco, California, United States, 94111 United States, New Jersey VIA Pharmaceuticals Princeton, New Jersey, United States, 08540 Collapse << |
| NCT01877837 | Sickle Cell Disease | Phase 3 | Active, not recruiting | August 2019 | United States, New Jersey ... more >> Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 Collapse << |
| NCT00552188 | - | - | Completed | - | - |
| NCT00306202 | - | - | Active, not recruiting | - | - |
| NCT00352417 | - | - | Completed | - | - |
| NCT00352417 | Atherosclerosis | Phase 2 | Completed | - | Italy ... more >> Azienda Ospedali Riuniti Ancona Ancona, Italy Presidio Ospedaliero SS Filippo e Nicola Avezzano, Italy Centro Studi Sull'Invecchiamento Chieti Scalo, Italy Collapse << |
| NCT01021215 | - | - | Completed | - | - |
| NCT00575861 | Asthma | Phase 4 | Completed | - | United States, California ... more >> Arthur F Gelb Medical Corporation Lakewood, California, United States, 90712 Collapse << |
| NCT01021215 | Tobacco Use Disorder | Phase 1 Phase 2 | Completed | - | United States, New York ... more >> Weill Cornell Medical College in New York City, Cornell University New York, New York, United States, 10021 United States, Texas MD Anderson Cancer Center - Consortium Lead Organzation Houston, Texas, United States, 77030 Collapse << |
| NCT01123863 | - | - | Completed | - | United States, Tennessee ... more >> St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 Collapse << |
| NCT02055781 | Primary Myelofibrosis ... more >> Post-polycythemia Vera Myelofibrosis Post-essential Thrombocythemia Myelofibrosis Collapse << | Phase 3 | Terminated | - | - |
| NCT01130688 | Chronic Myelogenous Leukemia | Phase 1 | Terminated(Lack of enrollment) | - | United States, Massachusetts ... more >> University of Massachusetts Medical School Worcester, Massachusetts, United States, 01655 Collapse << |
| NCT02047149 | Chronic Myelogenous Leukemia | Phase 1 | Terminated(Low accrual) | - | United States, Massachusetts ... more >> University of Massachusetts Medical School Worcester, Massachusetts, United States, 01655 Collapse << |
| NCT02348203 | Current Every Day Smoker ... more >> Multiple Pulmonary Nodules Tobacco Smoking Tobacco Use Disorder Collapse << | Phase 2 | Recruiting | - | United States, Arizona ... more >> The University of Arizona Medical Center-University Campus Recruiting Tucson, Arizona, United States, 85724 Contact: Linda L. Garland 520-626-3434 lgarland@azcc.arizona.edu Principal Investigator: Linda L. Garland United States, California University of California Davis Comprehensive Cancer Center Recruiting Sacramento, California, United States, 95817 Contact: Jun Yan 530-752-5109 junyang@ucdavis.edu Principal Investigator: Jun Yan United States, Massachusetts Boston University School of Medicine Recruiting Boston, Massachusetts, United States, 02118 Contact: Avrum Spira 617-414-6960 aspira@bu.edu Principal Investigator: Avrum Spira Collapse << |
| NCT01369160 | - | - | Completed | - | United States, Georgia ... more >> Children's Healthcare of Atlanta/Emory University Atlanta, Georgia, United States, 30322 Children's Healthcare of Atlanta Atlanta, Georgia, United States, 30322 Collapse << |
| NCT01597401 | Sickle Cell Disease | Phase 1 | Completed | - | United States, Maryland ... more >> US National Institutes of Health - National Heart, Lung, and Blood Institute Bethesda, Maryland, United States, 20892 Collapse << |
| NCT01905787 | - | - | Recruiting | December 31, 2018 | United States, Michigan ... more >> Children's Hospital of Michigan, Detroit Medical Center - Wayne State University Not yet recruiting Detroit, Michigan, United States Contact: Sharada A Sarniak, MD Israel Pediatric Hematology Unit HaEmek Medical Center Recruiting Afula, Israel, 18101 Contact: Ariel Koren, MD 97246495576 koren_a@clalit.org.il Sub-Investigator: Carina Levin, MD Sub-Investigator: MIchael Ruimi, student Pediatric Hematology Unit - Schneider Children's Hospital - Beilinson Medical Center Not yet recruiting Petah Tikva, Israel Contact: Hanna Tamary, MD Sub-Investigator: Yohanna Yakubobich, MD Pediatric Hematology Unit - Dana Children's Hospital - Ichilov Medical Center Not yet recruiting Tel Aviv, Israel Contact: Ronit El Hasid Sub-Investigator: Dror Levin, MD Collapse << |
| NCT00002771 | Leukemia | Phase 3 | Unknown | - | Germany ... more >> III Medizinische Klinik Mannheim Mannheim, Germany, D-68135 Collapse << |
| NCT00000919 | HIV Infections | Not Applicable | Completed | - | - |
| NCT00002868 | Leukemia | Phase 3 | Completed | - | United States, New Jersey ... more >> Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 Riverview Medical Center - Booker Cancer Center Red Bank, New Jersey, United States, 07701 United Kingdom Royal Infirmary Glasgow, Scotland, United Kingdom, G4 0SF Collapse << |
| NCT00005823 | Leukemia Myel... more >>odysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms Collapse << | Phase 3 | Completed | - | United Kingdom ... more >> Queen Elizabeth Hospital at University of Birmingham Birmingham, England, United Kingdom, B15 2RR University College Hospital London, England, United Kingdom, WC1E 6AU University Hospital of Wales Cardiff, Wales, United Kingdom, CF14 4XN Collapse << |
| NCT00098358 | Acne Vulgaris | Phase 2 | Unknown | - | United States, California ... more >> Therapeutics Clinical Research San Diego, California, United States, 92123 United States, Georgia MedaPhase, Inc. Newnan, Georgia, United States, 30263 United States, Kentucky Dermatology Specialists, PSC Louisville, Kentucky, United States, 40202 United States, Minnesota Minnesota Clinical Study Center Fridley, Minnesota, United States, 55432 United States, New Mexico Academic Dermatology Associates Albuquerque, New Mexico, United States, 87106 United States, New York SUNY Downstate Medical Center Brooklyn, New York, United States, 11203 Dermatology Associates of Rochester Rochester, New York, United States, 14623 United States, Pennsylvania Milton S. Hersey Medical Center Hersey, Pennsylvania, United States, 17033-0850 United States, Tennessee Rivergate Dermatology Goodlettsville, Tennessee, United States, 37072 United States, Texas DermResearch, Inc. Austin, Texas, United States, 78759 J&S Studies, Inc. Bryan, Texas, United States, 77802 United States, Virginia Virginia Clinical Research, Inc. Norfolk, Virginia, United States, 23507 Collapse << |
| NCT00299065 | Asthma | Phase 1 Phase 2 | Completed | - | United States, California ... more >> Allergy & Asthma Specialist Medical Group Huntington Beach, California, United States, 92647 Allergy and Asthma Medical Group and Research Center San Diego, California, United States, 92123 United States, Colorado Colorado Allergy and Asthma Centers, PC Englewood, Colorado, United States, 80112 United States, Massachusetts Northeast Medical Research Associates North Dartmouth, Massachusetts, United States, 02747 United States, Minnesota Clinical Research Institute Minneapolis, Minnesota, United States, 55402 United States, Missouri The Clinical Research Center, L.L.C. St. Louis, Missouri, United States, 63141 United States, New Jersey Princeton Center for Clinical Research Skillman, New Jersey, United States, 08558 United States, Ohio Bernstein Clinical Research Center Cincinnati, Ohio, United States, 45231 United States, Oregon Allergy Associates Research Center Portland, Oregon, United States, 97213 United States, Texas Western Sky Medical Research El Paso, Texas, United States, 79902 Collapse << |
| NCT00358826 | Coronary Artery Disease | Phase 2 | Completed | - | United States, Florida ... more >> MIMA Century Research Associates Melbourne, Florida, United States, 32901 United States, Minnesota Minneapolis Heart Institute Minneapolis, Minnesota, United States, 55407 United States, Mississippi Cardiology Associates Research, LLC Tupelo, Mississippi, United States, 38801 United States, North Carolina LeBauer Cardiovascular Research Foundation Greensboro, North Carolina, United States, 27401 United States, Texas Victoria Heart and Vascular Center Victoria, Texas, United States, 77901 Canada, Alberta Foothills Medical Center Calgary, Alberta, Canada, T2N 2T9 Canada, British Columbia Victoria Heart Institute Foundation Victoria, British Columbia, Canada, V8R 4R2 Canada, Nova Scotia Queen Elizabeth II HSC Halifax, Nova Scotia, Canada, B3H 3A7 Canada, Quebec Montreal Heart Institute Montreal, Quebec, Canada, H1T 1C8 Notre Dame Hospital Montreal, Quebec, Canada, H2L 4M1 Hospital Sacre-Coeur Montreal, Quebec, Canada, H4J 1C5 Constituante Centre Hospitalier Regional De Lanaudiere Saint-Charles-Borromee, Quebec, Canada, J6E 6J2 Collapse << |
| NCT02845232 | - | - | Completed | - | France ... more >> Hospices Civils de Lyon - Centre Hospitalier Lyon Sud, 165 Chemin du Grand Revoyet Pierre-benite, France, 69310 Collapse << |
| NCT00493974 | Pulmonary Disease, Chronic Obs... more >>tructive Collapse << | Phase 3 | Terminated(Lack of feasibility... more >> due to low recruitment) Collapse << | - | United States, Alabama ... more >> University of Alabama Lung Health Center Birmingham, Alabama, United States, 35249 Veteran's Administration Medical Center Birmingham, Alabama, United States, 35294 United States, California LA BioMed at Harbor, University of California Los Angeles, California, United States, 90502 University of California San Francisco-Airway Clinical Research Center San Francisco, California, United States, 94143 United States, Colorado Denver Health Medical Center Denver, Colorado, United States, 80204 National Jewish Medical and Research Center Denver, Colorado, United States, 80206 Veteran's Administration Medical Center Denver, Colorado, United States, 80220 United States, Maryland University of Maryland Hospital Baltimore, Maryland, United States, 21201 United States, Massachusetts Fallon Clinic Boston, Massachusetts, United States, 01605 Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Veteran's Administration Medical Center Boston, Massachusetts, United States, 02132 United States, Michigan Veteran's Administration Medical Center Ann Arbor, Michigan, United States, 48105 University of Michigan Medical Center Ann Arbor, Michigan, United States, 48109 United States, Minnesota Veteran's Administration Medical Center Minneapolis, Minnesota, United States, 55417 HealthPartners Research Foundation Minneapolis, Minnesota, United States, 55440 Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Pennsylvania Temple University Lung Center Philadelphia, Pennsylvania, United States, 19140 University of Pittsburgh Emphysema Research Center Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00358826 | - | - | Completed | - | - |
| NCT00534625 | Asthma | Phase 2 | Completed | - | - |
| NCT01136941 | Sickle Cell Disease | Phase 1 | Completed | - | United States, Ohio ... more >> Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229 Collapse << |
| NCT00004897 | Esophageal Cancer | Phase 2 | Terminated(Institutional Revie... more >>w Board requested termination - all patients deceased and no new accrual.) Collapse << | - | United States, Illinois ... more >> Robert H. Lurie Comprehensive Cancer Center, Northwestern University Chicago, Illinois, United States, 60611 Collapse << |
| NCT00486343 | Asthma | Phase 4 | Terminated(Slower than anticip... more >>ated enrollment) Collapse << | June 2008 | United States, Massachusetts ... more >> Critical Therapeutics Lexington, Massachusetts, United States, 02421 Collapse << |
| NCT01711541 | Head and Neck Squamous Cell Ca... more >>rcinoma Stage IVA Oropharyngeal Carcinoma AJCC v7 Stage IVB Oropharyngeal Carcinoma AJCC v7 Collapse << | Phase 1 Phase 2 | Active, not recruiting | - | United States, Illinois ... more >> Northwestern University Chicago, Illinois, United States, 60611 University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637 NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois, United States, 60201 United States, Missouri Washington University School of Medicine Saint Louis, Missouri, United States, 63110 United States, North Carolina UNC Lineberger Comprehensive Cancer Center Chapel Hill, North Carolina, United States, 27599 Collapse << |
| NCT02017457 | Acute Myelogenous Leukemia ... more >> Myelodysplastic Syndrome Collapse << | Phase 2 | Active, not recruiting | August 2020 | Belgium ... more >> Ziekenhuis Netwerk Antwerpen Antwerpen, Belgium, 2060 AZ Sint-Jan Brugge Brugge, Belgium, 8000 Institut Jules Bordet Brussels, Belgium, 1000 Universitair Ziekenhuis Antwerpen Edegem, Belgium, 2650 Universitair Ziekenhuis Gent Gent, Belgium, 9000 Hopital de Jolimont Haine-St-Paul, Belgium, 7100 Universitair Ziekenhuis Brussel Jette, Belgium, 1090 Universitair Ziekenhuis Leuven Leuven, Belgium, 3000 CHU Liège Liège, Belgium, 4000 Hartziekenhuis Roeselare Menen Roeselare, Belgium, 8800 Cliniques Universitaires Saint-Luc Woluwe-Saint-Lambert, Belgium, 1200 CHU Mont-Godinne Yvoir, Belgium, 5530 Collapse << |
| NCT00056004 | Head and Neck Cancer ... more >> Lung Cancer Collapse << | Phase 2 | Completed | - | United States, Michigan ... more >> Barbara Ann Karmanos Cancer Institute Detroit, Michigan, United States, 48201-1379 Collapse << |
| NCT00481052 | Chronic Myeloid Leukemia | Phase 2 | Active, not recruiting | December 2018 | Italy ... more >> Dipartimento Area Medica P.O. Ascoli Piceno, Italy, 63100 Unità Operativa Ematologica - Università degli Studi di Bari Bari, Italy, 70124 Ospedali Riuniti Bergamo, Italy, 24100 stituto di Ematologia "Lorenzo e A. Seragnoli" - Università degli Studi di Bologna - Policlinico S. Orsola - Malpighi Bologna, Italy Sezione di Ematologia e Trapianti Spedali Civili Brescia, Italy, 21125 Azienda Spedali Civili Brescia, Italy, 25100 ASL N.8 - Ospedale "A. Businco" - Struttura Complessa di Ematologia e CTMO Cagliari, Italy Ospedale Ferrarotto Catania, Italy, 95124 Azienda Ospedaliera Pugliese Ciaccio Catanzaro, Italy, 88100 Sezione di Ematologia e Fisiopatologia delle Emostasi - Azienda Ospedaliera - Arcispedale S. Anna Ferrara, Italy Azienda Ospedaliera Universitaria - Università degli Studi di Napoli "Federico II" - Facoltà di Medicina e Chirurgia Napoli, Italy Ospedale S. Luigi Gonzaga Orbassano, Italy, 10043 La Maddalena Casa di Cura di Alta Specialità Dipartimento Oncologico di III Livello Palermo, Italy Unità Operativa Ematologia e Centro Trapianti - Dipartimento di Oncologia ed Ematologia - AUSL Ospedale di Piacenza Piacenza, Italy Ospedale S.Maria delle Croci Ravenna, Italy, 48100 Calabria Dipartimento Emato-Oncologia A.O."Bianchi-Melacrino-Morelli" Reggio Calabria, Italy Università La Cattolica del Sacro Cuore Roma, Italy, 00168 Complesso Ospedaliero S. Giovanni Addolorata Roma, Italy, 00184 Università degli Studi "Sapienza" - Dip Biotecnologie Cellulari ed Ematologia - Divisione di Ematologia Roma, Italy U.O. Ematologia, Azienda Ospedaliera Universitaria Senese Siena, Italy, 53100 Policlinico Universitario - Clinica Ematologia Udine, Italy, 33100 Policlinico G.B. Rossi Verona, Italy, 37134 Collapse << |
| NCT00493974 | - | - | Terminated(Lack of feasibility... more >> due to low recruitment) Collapse << | - | - |
| NCT00744692 | - | - | Completed | - | - |
| NCT00744692 | Non Malignant Disorders ... more >> Immunodeficiencies Congenital Marrow Failures Hemoglobinopathies Inborn Errors of Metabolism Sickle Cell Thalassemia Lysosomal Storage Disease Collapse << | Phase 1 | Completed | - | United States, North Carolina ... more >> Duke University Medical Center Pediatric Blood and Marrow Transplant Program Durham, North Carolina, United States, 27705 Collapse << |
| NCT00055874 | Leukemia | Phase 3 | Completed | - | - |
| NCT03500731 | Idiopathic Pulmonary Fibrosis ... more >> Emphysema or COPD Collapse << | Phase 1 Phase 2 | Recruiting | December 2026 | United States, Pennsylvania ... more >> UPMC Presbyterian Recruiting Pittsburgh, Pennsylvania, United States, 15214 Contact: John McDyer, MD 412-648-6161 mcdyerjf@upmc.edu Children's Hospital of Pittsburgh of UPMC Recruiting Pittsburgh, Pennsylvania, United States, 15224 Contact: Jason Rowan, RN 412-692-6195 jason.rowan@chp.edu Principal Investigator: Paul Szabolcs, MD Collapse << |
| NCT00002674 | Leukemia | Phase 2 | Completed | - | United States, Washington ... more >> Fred Hutchinson Cancer Research Center Seattle, Washington, United States, 98109 Collapse << |
| NCT00152113 | Sickle Cell Disease | Phase 1 | Completed | - | United States, Tennessee ... more >> St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 Collapse << |
| NCT03224429 | Sickle Cell Disease | Not Applicable | Completed | - | - |
| NCT01773187 | Primary Myelofibrosis ... more >> Post-polycythemia Vera Myelofibrosis Post-essential Thrombocythemia Myelofibrosis Collapse << | Phase 3 | Terminated | - | - |
| NCT03401112 | Sickle Cell Disease | Phase 2 | Recruiting | June 2019 | United States, Connecticut ... more >> University of Connecticut Health Center (UCONN Health) Recruiting Farmington, Connecticut, United States, 06030 Contact: Sasia Jones Principal Investigator: Biree Andemariam, MD United States, North Carolina East Carolina University Recruiting Greenville, North Carolina, United States, 27834 Contact: Kaitlyn Walker United States, South Carolina Medical University of South Carolina Recruiting Charleston, South Carolina, United States, 29425 Contact: Emily Warner United Kingdom Birmingham and Sandwell Recruiting Birmingham, United Kingdom Contact: Elizabeth Green Croydon University Hospital Recruiting Croydon, United Kingdom, CR7 7YE Contact: Linda Sawyer Darent Valley Hospital Recruiting Dartford, United Kingdom, DA2 8DA Whittington Hospital Recruiting London, United Kingdom, N19 5NF University College Hospital (UCLH) Recruiting London, United Kingdom, NW1 2BU Contact: Jaspreet Kaur University Hospital Lewisham Recruiting London, United Kingdom, SE13 6LH Kings College Hospital Recruiting London, United Kingdom, SE5 9RS Guy's and St Thomas Hospital Recruiting London, United Kingdom Contact: Jitka Fucikova Homerton Hospital Recruiting London, United Kingdom Contact: Anna Price Collapse << |
| NCT01932021 | Skin Ulcer | Not Applicable | Unknown | December 2014 | France ... more >> University Hospital, Caen Recruiting Caen, France, 14 000 Contact: Anne Dompmartin +33 2 31 27 25 09 dompmartin-a@chu-caen.fr Contact: Marianne Chopinaud +33 6 85 82 29 42 mariannechopinaud@hotmail.com Principal Investigator: Anne Dompmartin, MD Collapse << |
| NCT03128996 | Severe Sickle Cell Disease ... more >> Bone Marrow Failure Syndromes Metabolic Disorders Immunologic Disorders Hemoglobinopathies Non-malignant Disorders Collapse << | Phase 1 Phase 2 | Recruiting | April 2024 | United States, Missouri ... more >> Washington University School of Medicine Recruiting Saint Louis, Missouri, United States, 63110 Contact: Shalini Shenoy, MD 314-454-6018 shalinishenoy@wustl.edu Contact: Lisa Murray, MA, CCRP 314-454-4240 murraylm@wustl.edu Principal Investigator: Shalini Shenoy, MD Collapse << |
| NCT03397017 | - | - | Active, not recruiting | December 31, 2020 | - |
| NCT01568645 | Pulmonary Hypertension | Phase 1 | Withdrawn | - | - |
| NCT03253211 | - | - | Recruiting | September 2020 | United States, North Carolina ... more >> Community Care of North Carolina Recruiting Raleigh, North Carolina, United States, 27607 Contact: Marian Earls Collapse << |
| NCT00333840 | Chronic Myelogenous Leukemia | Phase 3 | Completed | - | - |
| NCT02788201 | Urothelial Carcinoma ... more >> Bladder Cancer Urinary Bladder Neoplasms Collapse << | Phase 2 | Recruiting | July 1, 2020 | United States, Maryland ... more >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office 888-624-1937 Collapse << |
| NCT00101816 | Chronic Myeloid Leukemia ... more >> Blast Crisis Collapse << | Phase 2 | Completed | - | - |
| NCT00333840 | - | - | Completed | - | - |
| NCT01098084 | Chronic Myelomonocytic Leukemi... more >>a Collapse << | Phase 2 | Completed | - | France ... more >> CHU de Bicêtre Le Kremlin-Bicêtre, Ile de France, France, 94275 CHU d'Amiens Amiens, France, 80054 CH Angers Angers, France, 49 000 Hôpital Avignon Avignon, France, 84000 Hopital de la Cote Basque Bayonne, France, 64100 Hôpital Avicenne Bobigny, France, 93009 CHU Haut-Lévèque Bordeaux, France, 33604 Hôpital Boulogne Sur Mer Boulogne Sur Mer, France, 62321 Hopital d'Instruction des Armées Percy Clamart, France, 92140 CHU de Clermont Ferrand, France, 63058 Centre Hospitalier Sud-Francilien Corbeil-Essonnes, France, 91106 Hopital Henri Mondor Creteil, France, 94000 CHU de Dijon Dijon, France, 21034 Hôpital Versailles Le Chesnay, France, 78157 Centre Hospitalier du Mans Le Mans cedex, France, 72037 Institut Paoli Calmettes Marseille, France, 13009 CHU de nantes Nantes, France, 44093 Hôpital Archet1 Nice, France, 06202 CHU Caremeau Nimes, France, 30029 CHR La Source orléans Orléans, France, 45067 Hôpital Saint-Antoine. Paris-Cedex 12, France, 75571 Hopital Cochin Paris, France, 75014 Hopital Necker Paris, France, 75015 Hopital Hotel Dieu Paris, France, 75181 Hoiptal St Louis Paris, France, 75475 Centre Hospitalier Joffre Perpignan, France, 66046 CHU de Reims Reims, France, 51092 Centre Henri Becquerel Rouen, France, 76038 Hematology Dpt, Hopital Purpan Toulouse, France, 40031 CHU Bretoneau Tours, France, 37044 Institut gustave Roussy Villejuif, France, 94805 Collapse << |
| NCT00101816 | - | - | Completed | - | - |
| NCT00101647 | Chronic Myelogenous Leukemia | Phase 2 | Completed | - | - |
| NCT01657682 | Acute Myeloid Leukemia With FL... more >>T3 Activating Mutations That Has Relapsed or Been Refractory After One or More Prior Therapies Collapse << | Phase 2 | Active, not recruiting | April 2019 | United States, Texas ... more >> MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00494585 | Leukemia Myel... more >>ofibrosis Collapse << | Phase 2 | Completed | - | United States, Texas ... more >> The University of Texas M.D. Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00008047 | Esophageal Cancer | Phase 1 Phase 2 | Unknown | - | France ... more >> Hopital Saint-Louis Amiens, France, 80054 Cedex 1 Clinique Saint Vincent Besancon, France, 25044 Clinique Saint - Jean Cagne-sur-Mer, France, 06800 CHR de Grenoble - La Tronche Grenoble, France, F-38043 Hopital Andre Mignot Le Chesnay, France, 78157 CMC Les Ormeaux Le Havre, France, 76600 Centre Jean Bernard Le Mans, France, 72000 Hopital Laennec Paris, France, 75007 Hopital Saint Antoine Paris, France, 75571 Hopital Tenon Paris, France, 75970 Clinique Ste - Marie Pontoise, France, 95301 Polyclinique De Courlancy Reims, France, F-51100 C.H. Senlis Senlis, France, 60309 Clinique Fleming Tours, France, 37000 Collapse << |
| NCT01114087 | Chronic Myeloid Leukemia ... more >> Gastrointestinal Stromal Tumors Collapse << | Not Applicable | Completed | - | France ... more >> Department of Biology of reproduction (TENON Hospital-APHP) Paris, France, 75012 Collapse << |
| NCT02475993 | Sickle Cell Disease | Not Applicable | Recruiting | August 31, 2019 | United States, North Carolina ... more >> Duke University Medical Center Recruiting Durham, North Carolina, United States, 27710 Contact: Nirmish Shah, MD 919-684-8111 nirmish.shah@dm.duke.edu Contact: Betty Thames, BSN 919-681-9564 elizabeth.thames@dm.duke.edu Collapse << |
| NCT01668173 | Myeloproliferative Neoplasms | Phase 2 | Terminated(patient safety) | - | United States, New York ... more >> Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 Collapse << |
| NCT02101268 | Primary Myelofibrosis (PMF) ... more >> Post-polycythemia Vera (Post-PV) Post-essential Thrombocythemia Myelofibrosis (Post-ET MF) Collapse << | Phase 3 | Active, not recruiting | March 2019 | - |
| NCT00452023 | Myeloproliferative Disorders | Phase 2 | Active, not recruiting | December 2019 | United States, Texas ... more >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT01828619 | - | - | Unknown | - | China ... more >> Peking University People's Hospital Beijing, China, 100044 Collapse << |
| NCT00494585 | - | - | Completed | - | - |
| NCT00017862 | Hypereosinophilic Syndrome | Phase 2 | Completed | - | United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00101647 | - | - | Completed | - | - |
| NCT00040456 | HEMOGLOBIN SC DISEASE | Phase 2 | Terminated(Lack of accrual) | - | United States, Massachusetts ... more >> Children's Hospital Boston, Massachusetts, United States, 02115 United States, Texas Texas Children's Hospital Houston, Texas, United States, 77030 Collapse << |
| NCT01668173 | - | - | Terminated(patient safety) | - | - |
| NCT02989701 | Sickle Cell Disease Without Cr... more >>isis Collapse << | Phase 1 | Completed | - | United States, Massachusetts ... more >> Boston Childrens Hospital Boston, Massachusetts, United States, 02115 Collapse << |
| NCT00949364 | Myeloproliferative Neoplasms | Phase 2 | Completed | - | Germany ... more >> Universitätsklinikum Aachen Aachen, Germany, 52074 Charité Universitätsmedizin Berlin Berlin, Germany, 13353 Zentrum für Ambulante Hämatologie und Onkologie Bonn, Germany, 53119 BAG Freiberg-Richter, Jacobasch, Wolf, Illmer (Gemeinschaftspraxis) Dresden, Germany, 01307 Universitätsklinikum Düsseldorf Düsseldorf, Germany, 40225 Klinikum der Johann Goethe-Universität Frankfurt Frankfurt, Germany, 60590 Universitätsklinikum Freiburg Freiburg, Germany, 79106 Universitätsklinikum Hamburg Eppendorf Hamburg Eppendorf, Germany, 20246 Universitätsklinikum Jena Jena, Germany, 07740 Universitätsklinikum Magdeburg AöR Magdeburg, Germany, 39120 Universitätsmedizin Mannheim Mannheim, Germany, 68167 Johannes Wesling Klinikum Minden Minden, Germany, 32429 Stauferklinikum Schwäbisch Gmünd Mutlangen, Germany, 73557 Haematologisch-onkologische Praxis München, Germany, 80331 Universitätsklinikum Ulm Ulm, Germany, 89081 Collapse << |
| NCT00531310 | Chronic Myeloid Leukemia | Phase 2 | Terminated(Poor accrual) | - | United States, New York ... more >> Morgan Stanley Children's Hospital of NYP New York, New York, United States, 10032 Collapse << |
| NCT02809274 | - | - | Unknown | August 2018 | Israel ... more >> Emek Medical center Not yet recruiting Afula, Israel Contact: Evgeni Chubar, Dr Soroka medical center Not yet recruiting Beer Sheva, Israel Contact: Anna Gurevich Hillel Yaffe Medical Center Not yet recruiting Hadera, Israel Contact: Lea Arbov Bnei Zion medical center Not yet recruiting Haifa, Israel Contact: Yelena Mischenko, Dr Rambam Medical center Not yet recruiting Haifa, Israel Contact: Noa Lavi Meir Medical center Not yet recruiting Kfar Saba, Israel Contact: Martin Ellis, Prof Principal Investigator: Martin Ellis Sheba medical center Not yet recruiting Ramat Gan, Israel Contact: Adrian Duek Kaplan medical center Not yet recruiting Rehovot, Israel Contact: Anfisa Santevsky, Dr Maccabi Not yet recruiting Tel Aviv, Israel Contact: Sigal Tavor, Dr Sub-Investigator: Shirly Shapira, Dr Tel Aviv Sourasky Not yet recruiting Tel Aviv, Israel Contact: Irit Avivi, Prof Ziv Medical center Not yet recruiting Zefat, Israel Contact: Nagib Dali Assaf Harofeh Medical Center Not yet recruiting Zerifin, Israel Contact: Odit Gotvin, Dr Collapse << |
| NCT01461837 | Sickle Cell Disease | Phase 2 | Recruiting | April 2019 | United States, California ... more >> University of California Los Angeles (UCLA) Recruiting Los Angeles, California, United States, 90095 Contact: Theodore Moore, MD 310-825-6708 tbmoore@mednet.ucla.edu Contact: LaMarr Taylor, CCRP 310-794-8929 LaMarrTaylor@mednet.ucla.edu Principal Investigator: Theodore Moore, MD Children's Hospital and Research Center Oakland Completed Oakland, California, United States, 94609 United States, Illinois Lurie Children's Hospital Completed Chicago, Illinois, United States, 60611-2605 United States, Missouri Washington University/St. Louis Children's Hospital Recruiting Saint Louis, Missouri, United States, 63110 Contact: Shalini Shenoy, MD 314-454-6018 Shenoy@kids.wustl.edu Contact: Megan Holtmann 314-454-6018 Principal Investigator: Shalini Shenoy, MD United States, New York New York Medical College Recruiting Valhalla, New York, United States, 10595 Contact: Mitchell S Cairo, MD 914-594-2150 mitchell_cairo@nymc.edu Contact: Sandi Fabricatore, RN, PNP 914-594-2152 Fabricatores@wcmc.com Principal Investigator: Mitchell S Cairo, MD United States, Ohio Cincinnati Children's Hospital Withdrawn Cincinnati, Ohio, United States, 45229 United States, Wisconsin Medical College of Wisconsin/Children's Hospital of Wisconsin Recruiting Milwaukee, Wisconsin, United States, 53226 Contact: Julie Talano, MD 414-955-4185 jtalano@mcw.edu Contact: Kathy Jodarski 414-266-2681 kjodarski@chw.org Principal Investigator: Julie Talano, MD Collapse << |
| NCT00001108 | HIV Infections | Phase 1 | Completed | - | United States, Alabama ... more >> Univ of Alabama at Birmingham - Pediatric Birmingham, Alabama, United States, 35233 United States, California UCLA Med Ctr / Pediatric Los Angeles, California, United States, 900951752 United States, Florida Univ of Miami (Pediatric) Miami, Florida, United States, 33161 Sacred Heart Children's Hosp / CMS of Florida Pensacola, Florida, United States, 32503 United States, Illinois Cook County Hosp Chicago, Illinois, United States, 60612 Chicago Children's Memorial Hosp Chicago, Illinois, United States, 606143394 United States, Louisiana Tulane Univ / Charity Hosp of New Orleans New Orleans, Louisiana, United States, 701122699 United States, Maryland Johns Hopkins Hosp - Pediatric Baltimore, Maryland, United States, 212874933 United States, Massachusetts Children's Hosp of Boston Boston, Massachusetts, United States, 021155724 Univ of Massachusetts Med School Worcester, Massachusetts, United States, 016550001 United States, Mississippi Univ of Mississippi Med Ctr Jackson, Mississippi, United States, 39213 United States, New Jersey Univ of Medicine & Dentistry of New Jersey / Univ Hosp Newark, New Jersey, United States, 071032714 United States, New York North Shore Univ Hosp Great Neck, New York, United States, 11021 Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 Columbia Presbyterian Med Ctr New York, New York, United States, 10032 Incarnation Children's Ctr / Columbia Presbyterian Med Ctr New York, New York, United States, 10032 SUNY Health Sciences Ctr at Syracuse / Pediatrics Syracuse, New York, United States, 13210 United States, Tennessee Saint Jude Children's Research Hosp of Memphis Memphis, Tennessee, United States, 381052794 United States, Virginia Med College of Virginia Richmond, Virginia, United States, 23219 Collapse << |
| NCT01369368 | Acute Myeloid Leukemia | Phase 1 Phase 2 | Recruiting | October 2020 | Norway ... more >> Haukeland University Hospital Recruiting Bergen, Norway, N-5021 Principal Investigator: Oystein Bruserud, MD Collapse << |
| NCT02844218 | - | - | Completed | - | France ... more >> Hospices Civils de Lyon - Centre Hospitalier Lyon Sud, 165 Chemin du Grand Revoyet Pierre-benite, France, 69310 Collapse << |
| NCT02386657 | - | - | Completed | - | Belgium ... more >> CHU Brugmann Brussels, Belgium, 1020 Collapse << |
| NCT00511121 | Chronic Myeloid Leukemia | Phase 2 | Terminated | - | - |
| NCT00086658 | Hypereosinophilia ... more >> Hypereosinophilic Syndrome Collapse << | Phase 2 | Completed | - | - |
| NCT03040908 | - | - | Not yet recruiting | April 30, 2020 | - |
| NCT03007849 | - | - | Unknown | December 2017 | - |
| NCT03350152 | - | - | Completed | - | France ... more >> CORTIAL Pierre-Bénite, Rhone, France, 69310 Collapse << |
| NCT01440374 | Thrombocytopaenia | Phase 2 | Completed | - | - |
| NCT03280888 | - | - | Recruiting | November 5, 2018 | France ... more >> CHU de Nice Recruiting Nice, France, 06000 Contact: Laurence Legros, PH +33 (0)04 92 03 58 41 legros.l@chu-nice.fr Collapse << |
| NCT00131560 | HIV Infection | Phase 2 | Active, not recruiting | June 2023 | United States, California ... more >> Stanford AIDS Clinical Trials Unit Palo Alto, California, United States, 94304 United States, Connecticut CIRCLE Medical, LLC Norwalk, Connecticut, United States, 06851 United States, Florida Steinhart Medical Associates Miami, Florida, United States, 33133 United States, Kentucky University of Kentucky Lexington, Kentucky, United States, 40536 United States, New York Jacobi Medical Center Bronx, New York, United States, 10461 Collapse << |
| NCT02720679 | - | - | Recruiting | August 2026 | United States, Tennessee ... more >> St. Jude Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Contact: Jeremie Estepp, MD 866-278-5833 referralinfo@stjude.org Principal Investigator: Jeremie Estepp, MD Collapse << |
| NCT03247218 | Sickle Cell Disease | Phase 2 | Not yet recruiting | June 30, 2020 | - |
| NCT02165007 | Sickle Cell-thalassemia Diseas... more >>e Thalassemia Collapse << | Phase 1 | Recruiting | April 2023 | United States, District of Col... more >>umbia Childrens National Medical Center Recruiting Washington, District of Columbia, United States, 20010 Collapse << |
| NCT02466555 | Sickle Cell Disease | Not Applicable | Completed | - | United States, Ohio ... more >> University Hospitals Seidman Cancer Center Cleveland, Ohio, United States, 44106 Collapse << |
| NCT01440374 | - | - | Completed | - | - |
| NCT02776202 | Sickle Cell Disease | Phase 2 | Recruiting | December 2019 | Saudi Arabia ... more >> King Abdul Aziz Medical City for National Guard Recruiting Riyadh, Saudi Arabia Contact: Nagham RZ Sheblaq 009668011111 ext 53352 sheblaqn@ngha.med.sa Contact 009668011111 ext 53352 sheblaqn@ngha.med.sa Principal Investigator: Nagham RZ Sheblaq, BS.c Collapse << |
| 靶点 | Description | IC50 |
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