CAS No.: 1285702-20-6
ML167 Catalog No. CSN17183
Synonyms: CID44968231;NCGC00188654
ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, showing > 10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 作用机制
- 参考文献
- [1] Rosenthal AS, Tanega C, et al. An inhibitor of the Cdc2-like kinase 4 (Clk4). 2010 Mar 29 [updated 2011 Mar 3] .
- [2] Moyano, P. M. et al. Cdc-Like Kinases (CLKs): Biology, Chemical Probes, and Therapeutic potential. Int. J. Mol. Sci. 2020, 21(20), 7549.
- [3] Rosenthal AS, Tanega C, Shen M, Mott BT, Bougie JM, Nguyen DT, Misteli T, Auld DS, Maloney DJ, Thomas CJ. An inhibitor of the Cdc2-like kinase 4 (Clk4). 2010 Mar 29 [updated 2011 Mar 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 21735605.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1285702-20-6 | 储存条件 |
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| 分子式 | C19H17N3O3 | 运输 | 蓝冰 | |
| 分子量 | 335.36 | 别名 | CID44968231;NCGC00188654 |
