CAS No.: 115104-28-4
MK571 Catalog No. CSN20532
Synonyms: L-660711;L-660,711;MK-0571
MK-571 sodium is a selective, orally active CysLT1 receptor antagonist, which blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
靶点 LTD4/LTR1
Ki:0.22nMLTD4/LTR1 (guinea pig)
Ki:2.1nM- 描述
- 参考文献
- [1] Vellenga E, Tuyt L, et al. Interleukin-6 production by activated human monocytic cells is enhanced by MK-571, a specific inhibitor of the multi-drug resistance protein-1. Br J Pharmacol. 1999 May;127(2):441-8.
- [2] Metters KM, Zamboni RJ. Photoaffinity labeling of the leukotriene D4 receptor in guinea pig lung. J Biol Chem. 1993 Mar 25;268(9):6487-95.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 115104-28-4 | 储存条件 |
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| 分子式 | C26H27ClN2O3S2 | 运输 | 蓝冰 | |
| 分子量 | 515.09 | 别名 | L-660711;L-660,711;MK-0571;Verlukast |
