CAS No.: 892549-43-8
MF63 Catalog No. CSN18534
MF63 is a selective mPGES-1 inhibitor with an IC50 of 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Baragatti B, Scebba F, et al. Dual, constrictor-to-dilator, response of the mouse ductus arteriosus to the microsomal prostaglandin E synthase-1 inhibitor, 2-(6-chloro-1H phenanthro[9,10d] imidazole- 2-yl)isophthalonitrile. Neonatology.
- [2] Côte B, Boulet L, et al. Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6816-20.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 892549-43-8 | 储存条件 |
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| 分子式 | C23H11ClN4 | 运输 | 蓝冰 | |
| 分子量 | 378.81 | 别名 |
