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CAS No.: 2124-57-4
Synonyms: Vitamin K2-7;Vitamin K2(35);Vitamin MK-7
Menaquinone-7 is a long-chain menaquinone member of Vitamin K2, showing anti-cancer activity.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT00960973 | Diabetes Pred... more >>iabetic State Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> Seoul National University Medical School Seoul, Korea, Republic of Collapse << |
NCT03285100 | - | - | Recruiting | October 1, 2018 | Netherlands ... more >> Canisius Wilhelmina Hospital Recruiting Nijmegen, Netherlands, 6532SZ Contact: Rob Janssen, MD, PhD +31-24-3658755 rob.janssen@cwz.nl Principal Investigator: Rob Janssen, MD, PhD Principal Investigator: Ianthe Piscaer, MD Principal Investigator: Ruben Zaal, MD Collapse << |
NCT02336087 | Pancreatic Adenocarcinoma ... more >> Unresectable Pancreatic Carcinoma Collapse << | Phase 1 | Recruiting | August 2019 | United States, California ... more >> City of Hope Medical Center Recruiting Duarte, California, United States, 91010 Contact: Vincent Chung 626-471-9200 vchung@coh.org Principal Investigator: Vincent Chung City of Hope Rancho Cucamonga Recruiting Rancho Cucamonga, California, United States, 91730 Contact: Valerie Estala 626-256-4673 ext 81699 Sub-Investigator: Behnam Ebrahimi, MD City of Hope South Pasadena Recruiting South Pasadena, California, United States, 91030 Contact: Odessa Rodriguez 626-256-4673 ext 81409 orodriguez@coh.org Sub-Investigator: Christina Yeon, MD City of Hope West Covina Recruiting West Covina, California, United States, 91790 Contact: Meizi Zheng 626-256-4673 ext 81336 Sub-Investigator: Gargi Upadhyaya, MD Collapse << |
实验方案
技术信息
CAS号 | 2124-57-4 | 储存条件 |
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分子式 | C46H64O2 | 运输 | 蓝冰 | |||||
分子量 | 649.00 | 别名 | Vitamin K2-7;Vitamin K2(35);Vitamin MK-7;4-Naphthalenedione;Menaquinone K7;MK-7;甲基萘醌-7 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00960973 | Diabetes Pred... more >>iabetic State Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> Seoul National University Medical School Seoul, Korea, Republic of Collapse << |
NCT03285100 | - | - | Recruiting | October 1, 2018 | Netherlands ... more >> Canisius Wilhelmina Hospital Recruiting Nijmegen, Netherlands, 6532SZ Contact: Rob Janssen, MD, PhD +31-24-3658755 rob.janssen@cwz.nl Principal Investigator: Rob Janssen, MD, PhD Principal Investigator: Ianthe Piscaer, MD Principal Investigator: Ruben Zaal, MD Collapse << |
NCT02336087 | Pancreatic Adenocarcinoma ... more >> Unresectable Pancreatic Carcinoma Collapse << | Phase 1 | Recruiting | August 2019 | United States, California ... more >> City of Hope Medical Center Recruiting Duarte, California, United States, 91010 Contact: Vincent Chung 626-471-9200 vchung@coh.org Principal Investigator: Vincent Chung City of Hope Rancho Cucamonga Recruiting Rancho Cucamonga, California, United States, 91730 Contact: Valerie Estala 626-256-4673 ext 81699 Sub-Investigator: Behnam Ebrahimi, MD City of Hope South Pasadena Recruiting South Pasadena, California, United States, 91030 Contact: Odessa Rodriguez 626-256-4673 ext 81409 orodriguez@coh.org Sub-Investigator: Christina Yeon, MD City of Hope West Covina Recruiting West Covina, California, United States, 91790 Contact: Meizi Zheng 626-256-4673 ext 81336 Sub-Investigator: Gargi Upadhyaya, MD Collapse << |
NCT00165633 | Hepatocellular Carcinoma | Phase 2 Phase 3 | Terminated | - | Japan ... more >> Fukuoka, Fukuoka-prefecture, Japan, 814-0133 Kurume, Fukuoka-prefecture, Japan, 830-0011 Naka, Hiroshima-prefecture, Japan, 730-001 Sapporo, Hokkaido-prefecture, Japan, 006-8111 Sapporo, Hokkaido-prefecture, Japan, 060-0033 Hitachi, Ibaraki-prefecture, Japan, 317-0077 Morioka, Iwate-prefecture, Japan, 020-0023 Kawasaki, Kanagawa-prefecture, Japan, 213-0001 Kanazawa, Kanazawa-prefecture, Japan, 920-0934 Senndai, Miyagi-prefecture, Japan, 980-0872 Niigata, Niigata-prefecture, Japan, 951-8122 Oita, Oita-prefecture, Japan, 879-5503 Kurashiki, Okayama-prefecture, Japan, 710-0052 Okayama, Okayama-prefecture, Japan, 700-0013 Okayama, Okayama-prefecture, Japan, 700-0014 Moriguchi, Osaka-prefecture, Japan, 570-0074 Osakasayama, Osaka-prefecture, Japan, 589-0014 Osaka, Osaka-prefecture, Japan, 537-0025 Osaka, Osaka-prefecture, Japan, 543-0021 Osaka, Osaka-prefecture, Japan, 543-0027 Saga, Saga-prefecture, Japan, 840-0054 Saga, Saga-prefecture, Japan, 849-0937 Shizuoka, Shizuoka-prefecture, Japan, 420-0881 Bunkyo-ku, Tokyo, Japan, 113-0033 Chiyoda-ku, Tokyo, Japan, 101-0024 Setagaya-ku, Tokyo, Japan, 158-0098 Shibuya-ku, Tokyo, Japan, 151-0053 Shinjuku-ku, Tokyo, Japan, 162-0052 Wakayama, Wakayama-prefecture, Japan, 641-0012 Ube, Yamaguchi-prefecture, Japan, 755-0046 Collapse << |
NCT01922804 | Metabolic Bone Disorder | Not Applicable | Unknown | April 2018 | Denmark ... more >> Department of Endocrinology and Internal Medicine THG Aarhus, Denmark, 8000 Collapse << |
NCT01143831 | Thrombosis | Not Applicable | Completed | - | United States, North Carolina ... more >> University of North Carolina at Chapel Hill Chapel Hill, North Carolina, United States, 27599 Collapse << |
NCT02392767 | - | - | Completed | - | - |
NCT00290212 | Perimenopausal Bone Loss | Phase 2 | Completed | - | Norway ... more >> Haukeland University Hospital Bergen, Norway, NO 5021 Clinical Research Center, University Hospital of North Norway Tromsø, Norway, N-9038 Collapse << |
NCT01672099 | Vitamin K-status ... more >> Vascular Health Collapse << | Not Applicable | Completed | - | Netherlands ... more >> Vitak BV / Maastricht University Medical Center Maastricht, Netherlands, 6229 EV Collapse << |
NCT01638182 | Bone Health V... more >>ascular Health Collapse << | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV / Maastricht University Medicial Center Maastricht, Netherlands Collapse << |
NCT00548509 | Osteoporosis | Phase 4 | Completed | - | Japan ... more >> Kumagaya-shi, Saitama Prefecture, Japan, 350-0831 Hachioji-shi, Tokyo, Japan, 192-0065 Setagaya-Ku, Tokyo, Japan, 157-0066 Nishiyatsushiro-Gun, Yamanashi Prefecture, Japan, 409-3244 Collapse << |
NCT01232647 | Post-menopausal Osteoporosis | Phase 2 Phase 3 | Recruiting | March 2020 | United Kingdom ... more >> Guy's and St Thomas' Hospital NHS foundation Trust Recruiting London, United Kingdom, SE1 7EH Principal Investigator: Geeta Hampson, MD Osteoporosis Unit, Guy's Hospital Recruiting London, United Kingdom, SE1 9RT Contact: Amelia Moore, PhD 02071884092 amelia.moore@kcl.ac.uk Collapse << |
NCT02392767 | Endothelial Dysfunction ... more >> Hyperhomocysteinemia Hypertension Grade I, Subgroup "Borderline" (WHO) Collapse << | Not Applicable | Completed | - | Germany ... more >> BioTeSys Esslingen, Germany, 73728 Collapse << |
NCT01870115 | Osteoporosis ... more >>Osteopenia Collapse << | Phase 1 | Completed | - | United States, Pennsylvania ... more >> Duquesne University Center for Pharmacy Care Pittsburgh, Pennsylvania, United States, 15282 Collapse << |
NCT01407601 | CKD 5D, Hemodialysis | Phase 3 | Completed | - | Germany ... more >> KfH Dialysis Unit Aachen Aachen, NRW, Germany, 52074 University Hospital of the RWTH Aachen Aachen, NRW, Germany, 52074 Dialysis Unit Erkelenz Erkelenz, NRW, Germany, 41812 Collapse << |
NCT03311321 | Cardiovascular Diseases ... more >> Chronic Kidney Disease Stage 3 Chronic Kidney Disease Stage 4 Chronic Kidney Disease Stage 5 Vitamin K Deficiency Hemodialysis Collapse << | Phase 1 Phase 2 | Recruiting | December 2018 | United States, Georgia ... more >> Augusta University Recruiting Augusta, Georgia, United States, 30901 Collapse << |
NCT00931437 | Healthy | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV / University of Maastricht Maastricht, Netherlands Collapse << |
NCT01928134 | Healthy | Not Applicable | Completed | - | Taiwan ... more >> Changhua Christian Hospital Changhua, Taiwan, 500 Collapse << |
NCT01638143 | Bioequivalence ... more >> Bioavailability Collapse << | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV / Maastricht University Medical Center Maastricht, Netherlands Collapse << |
NCT00402974 | Healthy | Not Applicable | Completed | - | Netherlands ... more >> Wilhelmina Children's Hospital (WKZ), University Medical Center (UMC) Utrecht Utrecht, Netherlands, 3584 EA Collapse << |
NCT00512928 | Healthy | Not Applicable | Completed | - | Netherlands ... more >> Maastricht University Maastricht, Netherlands, 6200 MD Collapse << |
NCT02610933 | Vascular Calcification | Phase 4 | Unknown | December 2018 | Belgium ... more >> OLV Hospital Recruiting Aalst, Belgium, 9300 Contact: Rogier Caluwé, MD 003253724383 rogier.caluwe@olvz-aalst.be Collapse << |
NCT03243890 | Aortic Valve Stenosis ... more >> Multidetector Computed Tomography Vitamin K 2 Randomised Clinical Trial Collapse << | Phase 1 | Enrolling by invitation | December 2020 | Denmark ... more >> Department of Cardiology, Odense University Hospital Odense, Odense C, Denmark, DK-5000 Collapse << |
NCT02839044 | Arterial Calcification ... more >> Diabetes Mellitus Type 2 Collapse << | Not Applicable | Active, not recruiting | December 2018 | Netherlands ... more >> UMC Utrecht Utrecht, Netherlands Collapse << |
NCT02970084 | Carotid Plaques | Not Applicable | Active, not recruiting | July 2019 | Italy ... more >> San Raffaele Hospital Milano, Italy, 20132 Collapse << |
NCT02870829 | Vascular Calcification ... more >> Systemic and Arterial Stiffness Complication of Hemodialysis Deficiency of Vitamin K2 Collapse << | Phase 2 | Active, not recruiting | September 2019 | Singapore ... more >> National University Hospital Singapore, Singapore Collapse << |
NCT01873274 | Bioavailability | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV / Maastricht University Medical Center Maastricht, Netherlands, 6229 EV Collapse << |
NCT01194778 | Carboxylation Level ... more >> Vitamin K-dependent Proteins Collapse << | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV Maastricht University Maastricht, Netherlands, 6229 EV Collapse << |
NCT02976246 | Vitamin K Supplementation ... more >> Endstage Renal Disease Cardiovascular Disease Bone Disease Collapse << | Phase 2 Phase 3 | Recruiting | August 2020 | Denmark ... more >> Holbaek Hospital Not yet recruiting Holbaek, Denmark, 4300 Contact: Marianne Berthelsen, MDS mbte@regionsjaelland.dk Zealand University Hospital Recruiting Roskilde, Denmark, 4000 Contact: Karin Levy-Schousboe, phd student +45 23351803 kshb@regionsjaelland.dk Contact: Peter Marckmann, MDS +45 23351228 pmar@regionsjaelland.dk Collapse << |
NCT00483431 | Vitamin K-status | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV / University of Maastricht Maastricht, PO Box 616, Netherlands, 6200 MD Collapse << |
NCT01101698 | Kidney Diseases ... more >> Coronary Artery Calcification Collapse << | Phase 4 | Unknown | June 2011 | Poland ... more >> Department of Nephrology, Hypertension and Kidney Transplantation Recruiting Łódź, Poland, 90-153 Contact: Michał Nowicki, Prof 0048426776709 nefro@wp.pl Contact: Ilona Kurnatowska, MD 0048509293095 ilona.kurnatowska@umed.lodz.pl Principal Investigator: Michał Nowicki, Prof Collapse << |
NCT02876354 | Vascular Calcifications | Phase 4 | Completed | - | Lebanon ... more >> Saint-Georges Hospital Ajaltoun, Keserwan, Lebanon Collapse << |
NCT01972113 | Obesity Insul... more >>in Resistance Insulin Sensitivity Prediabetes Dyslipidemia Diabetes Collapse << | Phase 1 Phase 2 | Recruiting | December 2018 | United States, Georgia ... more >> Medical College of Georgia; Augusta University Recruiting Augusta, Georgia, United States, 30909 Principal Investigator: Norman K Pollock, Ph.D. Collapse << |
NCT02959762 | Obesity Insul... more >>in Resistance Obesity in Diabetes Nutritional and Metabolic Diseases Hyperlipidemia Hyperglycemia Cardiovascular Diseases Collapse << | Phase 1 Phase 2 | Recruiting | December 30, 2018 | United States, Georgia ... more >> Medical College of Georgia; Augusta University Recruiting Augusta, Georgia, United States, 30912 Contact: Norman K Pollock, Ph.D. 706-721-5424 npollock@augusta.edu Collapse << |
NCT01533441 | Thrombosis | Phase 2 | Completed | - | France ... more >> Unite de Recherches Therapeutiques, Hopital Lariboisiere Paris, France Collapse << |
NCT00742768 | Healthy | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV / Maastricht University Maastricht, Netherlands, 6200 MD Collapse << |
NCT01002157 | Coronary Artery Disease | Not Applicable | Active, not recruiting | October 2019 | Netherlands ... more >> Maastricht University Medical Center Maastricht, Netherlands, 6202 AZ Collapse << |
NCT02366481 | Obesity Insul... more >>in Resistance Insulin Sensitivity Beta-Cell Dysfunction Prediabetes Collapse << | Phase 1 Phase 2 | Recruiting | December 30, 2018 | United States, Georgia ... more >> Medical College of Georgia; Augusta University Recruiting Augusta, Georgia, United States, 30912 Contact: Norman K Pollock, Ph.D. 706-721-5424 npollock@augusta.edu Collapse << |
NCT00858767 | Bioavailability | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV /University of Maastricht Maastricht, Netherlands, PO Box 616 Collapse << |
NCT00732576 | Atherosclerosis | Not Applicable | Completed | - | Netherlands ... more >> VitaK - Maastricht University Maastricht, Netherlands, 6200 MD Collapse << |
NCT02517580 | Arterial Stiffness ... more >> Vitamin K2 Deficiency Collapse << | Phase 2 | Completed | - | Lebanon ... more >> Lebanese American University Medical Center - Rizk Hospital Ashrafieh, Beirut, Lebanon Collapse << |
NCT02917525 | Aortic Valve Stenosis ... more >> Bicuspid Aortic Valve Collapse << | Phase 2 | Recruiting | December 2019 | Netherlands ... more >> Maastricht UMC Recruiting Maastricht, Netherlands, 6202 AZ Contact: Bas Kietselaer, M.D., PhD +31 (0)43 3875093 b.kietselaer@mumc.nl Contact: Bas Kietselaer, M.D. PhD +31 (0)43 3875093 b.kietselaer@mumc.nl Sub-Investigator: Frederique Peeters, MD Collapse << |
NCT02517580 | - | - | Completed | - | - |
NCT01923012 | Carotid Disease ... more >> Atherosclerosis Collapse << | Phase 2 | Unknown | September 2015 | - |
NCT01675206 | Vascular Calcification | Phase 3 | Completed | - | - |
NCT03305536 | Aortic Valve Disease | Phase 2 | Recruiting | December 2020 | Lebanon ... more >> Hopital Saint-George Ajaltoun Recruiting Beirut, Lebanon Contact: Rodolphe Frangi, MD Collapse << |
NCT00642551 | Bone Loss Art... more >>eriosclerosis Collapse << | Not Applicable | Completed | - | Netherlands ... more >> VitaK BV / Maastricht University Maastricht, PO Box 616, Netherlands, 6200 MD Collapse << |
NCT02404519 | Vascular Stiffness | Not Applicable | Active, not recruiting | September 2018 | - |
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