CAS No.: 123642-27-3
MDL-73811 Catalog No. CSN20551
Synonyms: AbeAdo;MDL-73811
MDL 73811 is an inhibitor of S-adenosylmethionine decarboxylase for treating human african trypanosomiasis (HAT) caused by eukaryotic parasite Trypanosoma brucei.
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Brockway AJ, Volkov OA, et al. Synthesis and evaluation of analogs of 5'-(((Z)-4-amino-2-butenyl)methylamino)-5'-deoxyadenosine (MDL 73811, or AbeAdo) - An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity. Bioorg Med Chem. 2017 Aug 3. pii: S0968-0896(17)31301-9.
- [2] Byers TL, Casara P, Bitonti AJ. Uptake of the antitrypanosomal drug 5'-([(Z)-4-amino-2-butenyl] methylamino)-5'-deoxyadenosine (MDL 73811) by the purine transport system of Trypanosoma brucei brucei. Biochem J. 1992 May 1;283 (Pt 3):755-8.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 123642-27-3 | 储存条件 |
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| 分子式 | C15H23N7O3 | 运输 | 蓝冰 | |
| 分子量 | 349.39 | 别名 | AbeAdo;MDL-73811 |
