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CAS No.: 52665-74-4
Synonyms: NSC 622141;UCF 1C;手霉素A
Manumycin A is an antibiotic that acts as a potent and selective farnesyltransferase (FTase) inhibitor with anti-tumor activity. It inhibits rat brain FTase with a Ki value of 1.2 µM, thereby preventing Ras activation which requires farnesylation at the C-terminus for membrane attachment.
生物活性
实验方案
技术信息
CAS号 | 52665-74-4 | 储存条件 |
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分子式 | C31H38N2O7 | 运输 | 蓝冰 | |
分子量 | 550.64 | 别名 | NSC 622141;UCF 1C;手霉素A |
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