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CAS No.: 82034-46-6
Synonyms: Loteprednol etabonate;Lotemax;Alrex
Loteprednol etabonate is a corticosteroid with anti-inflammatory effect that is used in optometry and ophthalmology.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00905762 | Healthy | Phase 1 | Completed | - | United States, New York ... more >> Bausch & Lomb Incorporated Rochester, New York, United States, 14609 Collapse << |
NCT02163824 | Ocular Infections, Irritations... more >> and Inflammations Collapse << | Phase 3 | Completed | - | United States, California ... more >> Sall Research Medical Center Artesia, California, United States, 90701 North Valley Eye Medical Group Mission Hills, California, United States, 91345 Martel Eye Medical Group Rancho Cordova, California, United States, 95670 Wolstan & Goldberg Eye Associates Torrance, California, United States, 90505 United States, Georgia Clayton Eye Center Morrow, Georgia, United States, 30260 United States, Indiana Price Vision Group Indianapolis, Indiana, United States, 46260 John-Kenyon American Eye Institute New Albany, Indiana, United States, 47150 United States, Kentucky Taustine Eye Center Louisville, Kentucky, United States, 40217 United States, Missouri Tauber Eye Center Kansas City, Missouri, United States, 64111 Tekwani Vision Center Saint Louis, Missouri, United States, 63128 Ophthalmology Associates Saint Louis, Missouri, United States, 63131 Ophthalmology Consultants Saint Louis, Missouri, United States, 63131 United States, Nevada Las Vegas Physicians Research Group Henderson, Nevada, United States, 89052 United States, New York Raymond Fong, MDPC New York, New York, United States, 10013 Rochester Ophthalmological Group, PC Rochester, New York, United States, 14618 United States, North Carolina Cornerstone Eye Care High Point, North Carolina, United States, 27262 United States, Ohio Cincinnati Eye Institute Cincinnati, Ohio, United States, 45242 The Eye Center of Columbus Columbus, Ohio, United States, 43215 United States, South Carolina Westside Research, LLC Spartanburg, South Carolina, United States, 29306 United States, Texas The Eye Clinic of Texas, Affiliate of Houston Eye Associates League City, Texas, United States, 77573 R&R Eye Research, LLC San Antonio, Texas, United States, 78229 Kozlovsky Delay & Winter Eye Consultants, LLC San Antonio, Texas, United States, 78230 United States, Virginia Virginia Eye Consultants Norfolk, Virginia, United States, 23502 Collapse << |
NCT02813265 | Dry Eye Syndromes ... more >> Keratoconjunctivitis Sicca Collapse << | Phase 3 | Completed | - | - |
实验方案
技术信息
CAS号 | 82034-46-6 | 储存条件 |
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分子式 | C24H31ClO7 | 运输 | 蓝冰 | |||||||
分子量 | 466.95 | 别名 | Loteprednol etabonate;Lotemax;Alrex;HGP-1;Loterox;Locort | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00905762 | Healthy | Phase 1 | Completed | - | United States, New York ... more >> Bausch & Lomb Incorporated Rochester, New York, United States, 14609 Collapse << |
NCT02163824 | Ocular Infections, Irritations... more >> and Inflammations Collapse << | Phase 3 | Completed | - | United States, California ... more >> Sall Research Medical Center Artesia, California, United States, 90701 North Valley Eye Medical Group Mission Hills, California, United States, 91345 Martel Eye Medical Group Rancho Cordova, California, United States, 95670 Wolstan & Goldberg Eye Associates Torrance, California, United States, 90505 United States, Georgia Clayton Eye Center Morrow, Georgia, United States, 30260 United States, Indiana Price Vision Group Indianapolis, Indiana, United States, 46260 John-Kenyon American Eye Institute New Albany, Indiana, United States, 47150 United States, Kentucky Taustine Eye Center Louisville, Kentucky, United States, 40217 United States, Missouri Tauber Eye Center Kansas City, Missouri, United States, 64111 Tekwani Vision Center Saint Louis, Missouri, United States, 63128 Ophthalmology Associates Saint Louis, Missouri, United States, 63131 Ophthalmology Consultants Saint Louis, Missouri, United States, 63131 United States, Nevada Las Vegas Physicians Research Group Henderson, Nevada, United States, 89052 United States, New York Raymond Fong, MDPC New York, New York, United States, 10013 Rochester Ophthalmological Group, PC Rochester, New York, United States, 14618 United States, North Carolina Cornerstone Eye Care High Point, North Carolina, United States, 27262 United States, Ohio Cincinnati Eye Institute Cincinnati, Ohio, United States, 45242 The Eye Center of Columbus Columbus, Ohio, United States, 43215 United States, South Carolina Westside Research, LLC Spartanburg, South Carolina, United States, 29306 United States, Texas The Eye Clinic of Texas, Affiliate of Houston Eye Associates League City, Texas, United States, 77573 R&R Eye Research, LLC San Antonio, Texas, United States, 78229 Kozlovsky Delay & Winter Eye Consultants, LLC San Antonio, Texas, United States, 78230 United States, Virginia Virginia Eye Consultants Norfolk, Virginia, United States, 23502 Collapse << |
NCT02813265 | Dry Eye Syndromes ... more >> Keratoconjunctivitis Sicca Collapse << | Phase 3 | Completed | - | - |
NCT02793817 | Post Surgical Ocular Inflammat... more >>ion and Pain Collapse << | Phase 3 | Completed | - | - |
NCT00532961 | Inflammation | Phase 4 | Completed | - | - |
NCT02825186 | Ophthalmology | Not Applicable | Unknown | June 2018 | Israel ... more >> Department of Ophthalmology, Tel Aviv Sourasky Medical Center Not yet recruiting Tel Aviv, Israel, 64239 Contact: Gad Dotan, MD 972-3-6974165 gadd@tlvmc.gov.il Contact: Keren Elia Ogalbo 972-3-6974165 kernel@tlvmc.gov.il Collapse << |
NCT02245516 | Retinal Vein Occlusion ... more >> Diabetic Macular Edema Collapse << | Not Applicable | Completed | - | United States, California ... more >> Retina-Vitreous Associates Medical Group Beverly Hills, California, United States, 90211 United States, Massachusetts Ophthalmic Consultants of Boston Boston, Massachusetts, United States, 02114 Collapse << |
NCT02188160 | Dry Eye Syndromes ... more >> Keratoconjunctivitis Sicca Collapse << | Phase 2 | Completed | - | United States, California ... more >> Sall Research Medical Center Artesia, California, United States, 90701 North Valley Eye Medical Group Mission Hills, California, United States, 91345 Martel Eye Medical Group Rancho Cordova, California, United States, 95670 United States, Connecticut Eye Center of Southern CT, P.C. Hamden, Connecticut, United States, 06518 United States, Indiana Price Vision Group Indianapolis, Indiana, United States, 46260 United States, Missouri Ophthalmology Associates St. Louis, Missouri, United States, 63131 Comprehensive Eye Care, Ltd. / Vision Research Institute, LLC Washington, Missouri, United States, 63090 United States, New York South Shore Eye Center, LLP Wantagh, New York, United States, 11793 United States, Ohio Abrams Eye Center Cleveland, Ohio, United States, 44115 United States, Tennessee Total Eye Care, PA Memphis, Tennessee, United States, 38119 United States, Texas Whitsett Vision Group Houston, Texas, United States, 77055 Collapse << |
NCT02819284 | Dry Eye Syndromes ... more >> Keratoconjunctivitis Sicca Collapse << | Phase 3 | Completed | - | - |
NCT02218827 | Dry Eye | Not Applicable | Unknown | September 2015 | Israel ... more >> Meir Medical center Kfar Saba, Israel Sheba Medical Center Ramat Gan, Israel, 52621 Collapse << |
NCT00407043 | Dry Eye Disease ... more >> Keratoconjunctivitis Sicca Collapse << | Phase 4 | Completed | - | United States, New York ... more >> Ophthalmic Consultants of Long Island Lynbrook, New York, United States, 11563 Collapse << |
NCT00447577 | Blepharokeratoconjunctivitis | Phase 4 | Completed | - | United States, North Carolina ... more >> Cornerstone Eye Care High Point, North Carolina, United States, 27262 Collapse << |
NCT02218489 | Blepharitis | Phase 2 | Completed | - | United States, Alabama ... more >> UAB School of Optometry Birmingham, Alabama, United States, 35294-0010 United States, California Sall Research Medical Center Artesia, California, United States, 90701 North Valley Eye Medical Group Mission Hills, California, United States, 91345 Wolstan & Goldberg Eye Associates Torrance, California, United States, 90505 United States, Missouri Tauber Eye Center Kansas City, Missouri, United States, 64111 United States, New York South Shore Eye Center, LLP Wantagh, New York, United States, 11793 United States, Ohio Abrams Eye Center Cleveland, Ohio, United States, 44115 United States, Virginia Virginia Eye Consultants Norfolk, Virginia, United States, 23502 Collapse << |
NCT00689078 | Allergic Conjunctivitis | Phase 4 | Completed | - | United States, Massachusetts ... more >> Ophthalmic Research Associates Andover, Massachusetts, United States, 01810 Collapse << |
NCT01384266 | - | - | Completed | - | United States, Kentucky ... more >> Cincinnati Eye Institute Edgewood, Kentucky, United States, 41017 United States, Minnesota Associated Eye Care Stillwater, Minnesota, United States, 55082 Collapse << |
NCT00689078 | - | - | Completed | - | - |
NCT00366691 | Cataract Extraction | Phase 4 | Completed | - | United States, South Carolina ... more >> Storm Eye Institute, Medical University of South Carolina Charleston, South Carolina, United States, 29425 Collapse << |
NCT03464435 | Vernal Keratoconjunctivitis | Phase 4 | Completed | - | - |
NCT03098953 | Healthy | Phase 1 | Completed | - | United States, California ... more >> Valeant Site 01 Inglewood, California, United States, 90301 Collapse << |
NCT02786901 | Cataract Pain... more >> Ocular Inflammation Collapse << | Phase 3 | Completed | - | United States, Arizona ... more >> Valeant Site 01 Phoenix, Arizona, United States, 85032 United States, California Valeant Site 03 Oceanside, California, United States, 92056 United States, Florida Valeant Site 05 Miami, Florida, United States, 33143 United States, Massachusetts Valeant Site 04 Quincy, Massachusetts, United States, 02169 United States, Missouri Valeant Site 06 Kansas City, Missouri, United States, 64111 Valeant Site 02 Saint Louis, Missouri, United States, 63131 Collapse << |
NCT02120079 | Dry Eye Disease | Phase 4 | Completed | - | United States, Massachusetts ... more >> Tufts Medical Center Boston, Massachusetts, United States, 02111 Collapse << |
NCT00420628 | - | - | Completed | - | - |
NCT03123614 | Intraocular Pressure ... more >> Corneal Opacity Collapse << | Phase 4 | Completed | - | United States, Utah ... more >> Moran Eye Center - Midvalley Location Murray, Utah, United States, 84107 Collapse << |
NCT01028027 | Conjunctivitis ... more >> Keratitis Blepharitis Collapse << | Phase 3 | Completed | - | Singapore ... more >> Bausch & Lomb Inc Singapore, Singapore, 556741 Collapse << |
NCT01028027 | - | - | Completed | - | - |
NCT01853696 | Fuchs' Dystrophy ... more >> Corneal Edema Collapse << | Phase 4 | Completed | - | United States, Indiana ... more >> Price Vision Group Indianapolis, Indiana, United States, 46260 Collapse << |
NCT01724892 | Epithelial Defect After Photot... more >>herapeutic Keratectomy Collapse << | Phase 4 | Completed | - | Thailand ... more >> Onsiri Thanathanee Khon Kaen, Thailand, 40002 Srinagarind Hospital Khon Kaen, Thailand, 40002 Collapse << |
NCT02028312 | Dry Eye Disease | Phase 4 | Withdrawn(Per Sponsor) | June 2016 | United States, Kentucky ... more >> Cincinnati Eye Institute Edgewood, Kentucky, United States, 41017 Collapse << |
NCT02974387 | Must be PRK Candidate | Phase 4 | Unknown | November 2017 | - |
NCT00420628 | Chalazion Hor... more >>deolum Collapse << | Phase 4 | Completed | - | United States, Pennsylvania ... more >> Pediatric Ophthalmology of Erie Erie, Pennsylvania, United States, 16501 Collapse << |
NCT01853696 | - | - | Completed | - | - |
NCT01721694 | Ocular Inflammation ... more >> Infection Associated Blepharitis Keratitis Conjunctivitis, Bacterial Collapse << | Phase 3 | Withdrawn(withdrawn by industr... more >>y) Collapse << | May 2013 | Brazil ... more >> Department of Ophthalmology of Hospital São Paulo São Paulo, Brazil, 04023-062 Collapse << |
NCT01475643 | Cataract | Phase 3 | Active, not recruiting | August 2017 | United States, New York ... more >> Bausch & Lomb Inc Rochester, New York, United States, 14609 Collapse << |
NCT01193504 | Pseudophakia ... more >>Cataract Surgery Collapse << | Phase 4 | Unknown | October 2012 | United States, California ... more >> Harvard Eye Associates Recruiting Laguna Hills, California, United States, 92653 Contact: Melissa Earl 951-653-5566 m.earl@imedsonline.com Contact: Annie Christensen (951)653-5566 a.christensen@imedsonline.com Principal Investigator: John Hovanesian, MD United States, Florida The Center For Excellence in Eye care Recruiting Miami, Florida, United States, 33176 Contact: Melissa Earl 951-653-5566 m.earl@imedsonline.com Contact: Annie Christensen (951)653-5566 a.christensen@imedsonline.com Principal Investigator: William Trattler, MD Sub-Investigator: Carlos Buznego, MD United States, Massachusetts Ophthalmic Consultants of Boston Completed Waltham, Massachusetts, United States, 02451 Collapse << |
NCT01692652 | Moderate and Severe Meibomiang... more >> Gland Dysfunction (Stage 3 or Stage 4 Meibomiang Gland Dysfunction) Collapse << | Not Applicable | Completed | - | Korea, Republic of ... more >> department of Ophthalmology, Yonsei University College of Medicine Seoul, Korea, Republic of, 120-752 Collapse << |
NCT01437982 | Conjunctivitis, Seasonal Aller... more >>gic Conjunctivitis, Giant Papillary Inflammation Collapse << | Phase 4 | Active, not recruiting | April 2018 | Korea, Republic of ... more >> Bausch & Lomb Korea Ltd Seoul, Korea, Republic of, 135-280 Collapse << |
NCT00817557 | Contact Lenses Dryness | Phase 4 | Unknown | September 2009 | United States, California ... more >> Milton M. Hom, OD, FAAO. Azusa, California, United States, 91702 Collapse << |
NCT01456780 | Meibomian Gland Dysfunction ... more >> Posterior Blepharitis Collapse << | Phase 4 | Completed | - | United States, Massachusetts ... more >> Massachusetts Eye & Ear Infirmary Boston, Massachusetts, United States, 02114 Collapse << |
NCT01107405 | Allergic Conjunctivitis | Phase 2 | Completed | - | United States, New York ... more >> Bausch & Lomb Rochester, New York, United States, 14603 Collapse << |
NCT01736527 | Pharmacokinetics | Phase 1 | Completed | - | United States, New York ... more >> Bausch & Lomb Research Clinic Rochester, New York, United States, 14609 Collapse << |
NCT01456780 | - | - | Completed | - | - |
NCT00705159 | - | - | Completed | - | - |
NCT01107405 | - | - | Completed | - | - |
NCT00834171 | - | - | Completed | - | United States, Virginia ... more >> Maclean, Virginia, United States Collapse << |
NCT00705159 | Conjunctivitis | Phase 4 | Completed | - | United States, Pennsylvania ... more >> Pediatric Ophthalmology of Erie Erie, Pennsylvania, United States, 16501 Collapse << |
NCT00834171 | - | - | Completed | - | - |
NCT01817582 | Keratoconjunctivitis Sicca | Phase 2 | Completed | - | United States, California ... more >> Bausch & Lomb Incorporated Irvine, California, United States, 92618 Collapse << |
NCT01996839 | Inflammation ... more >>Pain Cataract Collapse << | Phase 3 | Completed | - | United States, New Jersey ... more >> Bausch & Lomb Incorporated Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT00781300 | Glaucoma, Open-Angle ... more >> Ocular Hypertension Collapse << | Phase 4 | Completed | - | Brazil ... more >> Department of Opthalmology, Federal University of São Paulo São Paulo, SP, Brazil, 04023-062 Collapse << |
NCT01010633 | Inflammation ... more >>Pain Collapse << | Phase 3 | Completed | - | United States, New York ... more >> Bausch & Lomb, Inc. Rochester, New York, United States, 14609 Collapse << |
NCT01010633 | - | - | Completed | - | - |
NCT01344226 | - | - | Completed | - | United States, Missouri ... more >> Discover Vision Centers Independence, Missouri, United States, 64055 Collapse << |
NCT02322528 | - | - | Completed | - | - |
NCT00645671 | Ocular Inflammation | Phase 3 | Completed | - | United States, Kansas ... more >> John Hunkeler, MD Overland Park, Kansas, United States, 66210 Collapse << |
NCT01736527 | - | - | Completed | - | - |
NCT00645671 | - | - | Completed | - | - |
NCT02322528 | Sjogren's Disease | Not Applicable | Completed | - | United States, New York ... more >> Flaum Eye Institute at the University of Rochester Rochester, New York, United States, 14642 Collapse << |
NCT01435460 | - | - | Completed | - | - |
NCT00560638 | Dry Eye | Phase 2 | Completed | - | United States, Massachusetts ... more >> Ophthalmic Research Associates Andover, Massachusetts, United States, 01810 Collapse << |
NCT01344226 | - | - | Completed | - | - |
NCT00699153 | Ocular Inflammation | Phase 3 | Completed | - | United States, North Carolina ... more >> Cornerstone Eye Wear High Point, North Carolina, United States, 27262 Collapse << |
NCT01443442 | Allergic Conjunctivitis | Phase 4 | Completed | - | United States, California ... more >> Eye Car Center, Southern California college of Optometry Fullerton, California, United States, 92831 Eye Care Center, Southern Caalifornia College of Optometry Fullerton, California, United States, 92831 Collapse << |
NCT00699153 | - | - | Completed | - | - |
NCT01060072 | - | - | Completed | - | - |
NCT01060072 | Inflammation ... more >>Pain Collapse << | Phase 3 | Completed | - | United States, New York ... more >> Bausch & Lomb Rochester, New York, United States, 14609 Collapse << |
NCT01435460 | Seasonal Allergic Conjunctivit... more >>is Collapse << | Phase 3 | Completed | - | Singapore ... more >> Bausch & Lomb Singapore Singapore, Singapore, 556741 Collapse << |
NCT03063489 | Eye Pain | Phase 1 | Completed | - | United States, Arizona ... more >> Valeant Site 01 Phoenix, Arizona, United States, 85032 United States, California Valeant Site 03 Oceanside, California, United States, 92056 United States, Florida Valeant Site 05 Miami, Florida, United States, 33143 United States, Massachusetts Valeant Site 04 Quincy, Massachusetts, United States, 01269 United States, Missouri Valeant Site 06 Kansas City, Missouri, United States, 64111 Valeant Site 02 St. Louis, Missouri, United States, 63131 Collapse << |
NCT01695668 | Dry Eyes | Not Applicable | Completed | - | - |
NCT02208297 | Inflammation ... more >>Pain Cataract Collapse << | Phase 3 | Completed | - | United States, New Jersey ... more >> Bausch & Lomb Incorporated Bridgewater, New Jersey, United States, 08807 Collapse << |
NCT03531697 | Inflammation Following Ocular ... more >>Surgery Collapse << | Phase 1 | Recruiting | February 15, 2019 | Canada ... more >> Sandoz Investigative Site Recruiting Multiple Locations, Canada Sandoz Investigative Site Not yet recruiting Multiple Locations, Canada Collapse << |
NCT01695668 | - | - | Completed | - | - |
NCT01749241 | Post-operative Healing Followi... more >>ng Blepharoplasty and Ptosis Repair Collapse << | Not Applicable | Unknown | September 2015 | United States, California ... more >> Shiley Eye Center Recruiting La Jolla, California, United States, 92093 Contact: Catherine Ledford, MBA 858-534-2109 cledford@ucsd.edu Contact: Caitlin Chu 858-534-6866 cvchu@ucsd.edu Principal Investigator: Bobby Korn, MD, PhD Sub-Investigator: Don Kikkawa, MD Collapse << |
靶点 | Description | IC50 |
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