400-920-2911 sales@csnpharm.cn
您的位置 : 首页 / Neuronal Signaling / 5-HT Receptor / Lecozotan
CAS No.: 434283-16-6
Synonyms: SRA-333
Lecozotan is a potent and selective 5-HT(1A) receptor antagonist. It significantly potentiated the potassium chloride-stimulated release of glutamate and acetylcholine in the dentate gyrus of the hippocampus. It produced a significant improvement in task performance efficiency at an optimal dose (1 mg/kg p.o.) in aged rhesus monkeys.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00538889 | Healthy | Phase 1 | Completed | - | United Kingdom ... more >> Manchester, United Kingdom Collapse << |
NCT00499642 | Alzheimer Disease ... more >> Healthy Collapse << | Phase 1 | Completed | - | France ... more >> Rennes, France, 35000 Rueil-Malmaison, France, 92502 Collapse << |
NCT00151398 | Alzheimer Disease | Phase 2 | Completed | - | - |
实验方案
技术信息
CAS号 | 434283-16-6 | 储存条件 |
|
|
分子式 | C28H29N5O3 | 运输 | 蓝冰 | |
分子量 | 483.56 | 别名 | SRA-333 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00538889 | Healthy | Phase 1 | Completed | - | United Kingdom ... more >> Manchester, United Kingdom Collapse << |
NCT00499642 | Alzheimer Disease ... more >> Healthy Collapse << | Phase 1 | Completed | - | France ... more >> Rennes, France, 35000 Rueil-Malmaison, France, 92502 Collapse << |
NCT00151398 | Alzheimer Disease | Phase 2 | Completed | - | - |
NCT00277810 | Alzheimer Disease | Phase 2 Phase 3 | Completed | - | - |
NCT00563732 | Alzheimer Disease | Phase 1 | Completed | - | - |
NCT00494962 | Alzheimer Disease | Phase 1 | Completed | - | Germany ... more >> Neuss, Germany, 41460 Collapse << |
NCT00366483 | Alzheimer Disease | Phase 1 | Completed | - | France ... more >> Paris, France Collapse << |
联系我们
官方电话:400-920-2911
二维码
微信公众号 CSN官网