CAS No.: 1152107-25-9
Lanopepden Catalog No. CSN20305
Synonyms: GSK 1322322;GSK-1322322B;GSK-322
GSK-1322322 is a potent and selective peptide deformylase inhibitor with good in vitro activity against bacteria associated with community-acquired pneumonia and skin infections. GSK1322322 has bactericidal activity against S. pneumoniae, H. influenzae, S. pyogenes, and S. aureus, demonstrating a ≥ 3-log (10) decrease in the number of CFU/mL at 4× MIC within 24 h in 29 of the 33 strains tested.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01953809 Infections, Bacterial Phase 1 Withdrawn(Emerging GSK1322322 ... more >>pre-clinical data ID'd potentially reactive metabolites previously not seen that changed the risk benefit profile and led to a termination) Collapse << March 2015 - NCT01209078 Skin Infections, Bacterial Phase 2 Completed - United States, Alabama ... more >> GSK Investigational Site Anniston, Alabama, United States, 36207 United States, California GSK Investigational Site Chula Vista, California, United States, 91911 GSK Investigational Site La Mesa, California, United States, 91942 GSK Investigational Site Long Beach, California, United States, 90813 GSK Investigational Site Oceanside, California, United States, 92056 United States, Hawaii GSK Investigational Site Honolulu, Hawaii, United States, 96813 United States, Pennsylvania GSK Investigational Site West Reading, Pennsylvania, United States, 19611 Collapse << NCT01803399 Infections, Bacterial Phase 1 Withdrawn(Emerging GSK1322322 ... more >>pre-clinical data ID'd potentially reactive metabolites previously not seen that changed the risk benefit profile and led to a termination) Collapse << December 2014 - - 更多
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1152107-25-9 | 储存条件 |
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| 分子式 | C22H34FN7O4 | 运输 | 蓝冰 | |
| 分子量 | 479.55 | 别名 | GSK 1322322;GSK-1322322B;GSK-322;GSK-1322322J |
