CAS No.: 1782235-14-6
Laduviglusib 3HCl Catalog No. CSN19149
Synonyms: CHIR-99021 trihydrochloride;CT99021 trihydrochloride;CHIR-911
CHIR-99021 3HCl is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM, showing > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases.
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400-920-2911
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Naujok O, Lentes J, et al. Cytotoxicity and activation of the Wnt/beta-catenin pathway in mouse embryonic stem cells treated with four GSK3 inhibitors. BMC Res Notes. 2014 Apr 29;7:273.
- [2] Ring DB, Johnson KW, et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1782235-14-6 | 储存条件 |
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| 分子式 | C22H21Cl5N8 | 运输 | 蓝冰 | |||||
| 分子量 | 574.72 | 别名 | CHIR-99021 trihydrochloride;CT99021 trihydrochloride;CHIR-911;CT- 99021;CHIR-73911;GSK 3 inhibitor XVI;GSK 3IXV | |||||
| 溶解度 |
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动物实验配方 |
